G3UX63 · G3UX63_MOUSE
- ProteinDNA methyltransferase 3A
- GeneDnmt3a
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids
- Protein existenceEvidence at protein level
- Annotation score1/5
Publications for G3UX63
Inflammatory signals from fatty bone marrow support DNMT3A driven clonal hematopoiesis.
- CategoriesFunction
- SourceMGI: 1261827
DNA Methylation-Dependent Restriction of Tyrosine Hydroxylase Contributes to Pancreatic beta-Cell Heterogeneity.
- CategoriesFunction, Expression
- SourceMGI: 1261827
Dynamics of DNA hydroxymethylation and methylation during mouse embryonic and germline development.
- CategoriesFunction
- SourceMGI: 1261827
Mitochondrial genome undergoes de novo DNA methylation that protects mtDNA against oxidative damage during the peri-implantation window.
- CategoriesFunction, Subcellular Location
- SourceMGI: 1261827
TET2-mutant clonal hematopoiesis and risk of gout.
- CategoriesFunction
- SourceMGI: 1261827
Constitutive loss of DNMT3A causes morbid obesity through misregulation of adipogenesis.
- CategoriesFunction, Phenotypes & Variants
- SourceMGI: 1261827
The disordered N-terminal domain of DNMT3A recognizes H2AK119ub and is required for postnatal development.
- CategoriesFunction, Expression, Phenotypes & Variants
- SourceMGI: 1261827
DNMT3A-dependent DNA methylation is required for spermatogonial stem cells to commit to spermatogenesis.
- CategoriesFunction, Phenotypes & Variants
- SourceMGI: 1261827
DNA Methyltransferase 3b in Myeloid Cells Does Not Affect the Acute Immune Response in the Airways during <i>Pseudomonas</i> Pneumonia.
- CategoriesFunction, Phenotypes & Variants
- SourceMGI: 1261827
Heterozygous Dnmt3a R878C induces expansion of quiescent hematopoietic stem cell pool.
- CategoriesFunction, Phenotypes & Variants
- SourceMGI: 1261827
Hotspot DNMT3A mutations in clonal hematopoiesis and acute myeloid leukemia sensitize cells to azacytidine via viral mimicry response.
- CategoriesFunction, Phenotypes & Variants
- SourceMGI: 1261827
SWI/SNF chromatin remodeling complex is required for initiation of sex- dependent differentiation in mouse germline.
- CategoriesFunction, Expression
- SourceMGI: 1261827
Gab2 deficiency prevents Flt3-ITD driven acute myeloid leukemia in vivo.
- CategoriesFunction, Phenotypes & Variants
- SourceMGI: 1261827
Gene expression levels of DNA methyltransferase enzymes in <i>Shank3</i>- deficient mouse model of autism during early development.
- CategoriesFunction, Expression
- SourceMGI: 1261827
Epigenetic interaction between UTX and DNMT1 regulates diet-induced myogenic remodeling in brown fat.
- CategoriesFunction, Phenotypes & Variants
- SourceMGI: 1261827
Dnmt3a-mutated clonal hematopoiesis promotes osteoporosis.
- CategoriesFunction
- SourceMGI: 1261827
Activation of <i>Notch</i> and <i>Myc</i> Signaling via B-cell-Restricted Depletion of <i>Dnmt3a</i> Generates a Consistent Murine Model of Chronic Lymphocytic Leukemia.
- CategoriesFunction, Phenotypes & Variants
- SourceMGI: 1261827
Analysis of Gene Expression Patterns of Epigenetic Enzymes <i>Dnmt3a</i>, <i>Tet1</i> and <i>Ogt</i> in Murine Chondrogenic Models.
- CategoriesFunction, Expression
- SourceMGI: 1261827
Functional and epigenetic phenotypes of humans and mice with DNMT3A Overgrowth Syndrome.
- CategoriesFunction, Phenotypes & Variants
- SourceMGI: 1261827