Early function of Pax5 (BSAP) before the pre-B cell receptor stage of B lymphopoiesis.Thevenin C., Nutt S.L., Busslinger M.View abstractCategoryFunctionSourceMGI: 97489PubMedEurope PMCJ Exp Med 188:735-744 (1998)Mapped to18
Identification of BSAP (Pax-5) target genes in early B-cell development by loss- and gain-of-function experiments.Nutt S.L., Morrison A.M., Dorfler P., Rolink A., Busslinger M.View abstractCategoryFunctionSourceMGI: 97489PubMedEurope PMCEMBO J 17:2319-2333 (1998)Mapped to18
PU.1 functions in a cell-autonomous manner to control the differentiation of multipotential lymphoid-myeloid progenitors.Scott E.W., Fisher R.C., Olson M.C., Kehrli E.W., Simon M.C., Singh H.View abstractCategoryFunctionSourceMGI: 97489PubMedEurope PMCImmunity 6:437-447 (1997)Mapped to37
Essential functions of Pax5 (BSAP) in pro-B cell development: difference between fetal and adult B lymphopoiesis and reduced V-to-DJ recombination at the IgH locus.Nutt S.L., Urbanek P., Rolink A., Busslinger M.View abstractCategoryFunctionSourceMGI: 97489PubMedEurope PMCGenes Dev. 11:476-491 (1997)Cited in1Mapped to17
Pax2 contributes to inner ear patterning and optic nerve trajectory.Torres M., Gomez-Pardo E., Gruss P.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 97489PubMedEurope PMCDevelopment 122:3381-3391 (1996)Mapped to35
The gene encoding the central cannabinoid receptor is located in proximal mouse Chromosome 4.Stubbs L., Chittenden L., Chakrabarti A., Onaivi E.CategoriesFunction, SequencesSourceMGI: 97489PubMedEurope PMCMamm Genome 7:165-166 (1996)Mapped to34
Loss of p53 function through PAX-mediated transcriptional repression.Stuart E.T., Haffner R., Oren M., Gruss P.View abstractCategoriesFunction, SequencesSourceMGI: 97489PubMedEurope PMCEMBO J 14:5638-5645 (1995)Mapped to42
Complete block of early B cell differentiation and altered patterning of the posterior midbrain in mice lacking Pax5/BSAP.Urbanek P., Wang Z.Q., Fetka I., Wagner E.F., Busslinger M.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 97489PubMedEurope PMCCell 79:901-912 (1994)Mapped to18
E2A proteins are required for proper B cell development and initiation of immunoglobulin gene rearrangements.Bain G., Maandag E.C., Izon D.J., Amsen D., Kruisbeek A.M., Weintraub B.C., Krop I., Schlissel M.S., Feeney A.J., van Roon M.View abstractCategoryFunctionSourceMGI: 97489PubMedEurope PMCCell 79:885-892 (1994)Mapped to43
Pax5 (BSAP) regulates the murine immunoglobulin 3' alpha enhancer by suppressing binding of NF-alpha P, a protein that controls heavy chain transcription.Neurath M.F., Max E.E., Strober W.View abstractCategoryFunctionSourceMGI: 97489PubMedEurope PMCProc Natl Acad Sci U S A 92:5336-5340 (1995)Mapped to18
B cell differentiation: role of E2A and Pax5/BSAP transcription factors.Baker S.J., Reddy E.P.View abstractCategoryFunctionSourceMGI: 97489PubMedEurope PMCOncogene 11:413-426 (1995)Mapped to18
Failure of B-cell differentiation in mice lacking the transcription factor EBF.Lin H., Grosschedl R.View abstractCategoryFunctionSourceMGI: 97489PubMedEurope PMCNature 376:263-267 (1995)Cited in1Mapped to45
Genetic determinants of micronucleus formation in vivo.Adams D.J., Barlas B., McIntyre R.E., Salguero I., van der Weyden L., Barros A., Vicente J.R., Karimpour N., Haider A.[...], White J.K.View abstractCategoryFunctionSourceMGI: 97489PubMedEurope PMCNature 627:130-136 (2024)Mapped to99+
Essential role of the Pax5 C-terminal domain in controlling B cell commitment and development.Gruenbacher S., Jaritz M., Hill L., Schafer M., Busslinger M.View abstractCategoryFunctionSourceMGI: 97489PubMedEurope PMCJ Exp Med 220:e20230260-e20230260 (2023)Mapped to19
Immune stress suppresses innate immune signaling in preleukemic precursor B-cells to provoke leukemia in predisposed mice.Isidro-Hernandez M., Casado-Garcia A., Oak N., Aleman-Arteaga S., Ruiz-Corzo B., Martinez-Cano J., Mayado A., Sanchez E.G., Blanco O.[...], Sanchez-Garcia I.View abstractCategoryFunctionSourceMGI: 97489PubMedEurope PMCNat Commun 14:5159-5159 (2023)Mapped to29
Enhancers of the PAIR4 regulatory module promote distal V<sub>H</sub> gene recombination at the Igh locus.Hill L., Jaritz M., Tagoh H., Schindler K., Kostanova-Poliakova D., Sun Q., Schwickert T.A., Leeb M., Busslinger M.View abstractCategoryFunctionSourceMGI: 97489PubMedEurope PMCEMBO J 42:e112741-e112741 (2023)Mapped to33
The Midbrain Preisthmus: A Poorly Known Effect of the Isthmic Organizer.Puelles L., Hidalgo-Sanchez M.View abstractCategoryFunctionSourceMGI: 97489PubMedEurope PMCInt J Mol Sci 24:9769-9769 (2023)Mapped to99+
Differential modularity of the mammalian Engrailed 1 enhancer network directs sweat gland development.Aldea D., Kokalari B., Atsuta Y., Dingwall H.L., Zheng Y., Nace A., Cotsarelis G., Kamberov Y.G.View abstractCategoriesFunction, ExpressionSourceMGI: 97489PubMedEurope PMCPLoS Genet 19:e1010614-e1010614 (2023)Mapped to29
Human midbrain dopaminergic neuronal differentiation markers predict cell therapy outcomes in a Parkinson's disease model.Xu P., He H., Gao Q., Zhou Y., Wu Z., Zhang X., Sun L., Hu G., Guan Q.[...], Chen Y.View abstractCategoryFunctionSourceMGI: 97489PubMedEurope PMCJ Clin Invest 132:e156768-e156768 (2022)Mapped to86
<i>Pax3</i> Hypomorphs Reveal Hidden Pax7 Functional Genetic Compensation <i>in Utero</i>.Zhou H.M., Conway S.J.View abstractCategoryFunctionSourceMGI: 97489PubMedEurope PMCJ Dev Biol 10:19-19 (2022)Mapped to62
The PAX5-JAK2 translocation acts as dual-hit mutation that promotes aggressive B-cell leukemia via nuclear STAT5 activation.Jurado S., Fedl A.S., Jaritz M., Kostanova-Poliakova D., Malin S.G., Mullighan C.G., Strehl S., Fischer M., Busslinger M.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 97489PubMedEurope PMCEMBO J 41:e108397-e108397 (2022)Mapped to31
Transient Inhibition of the JAK/STAT Pathway Prevents B-ALL Development in Genetically Predisposed Mice.Casado-Garcia A., Isidro-Hernandez M., Oak N., Mayado A., Mann-Ran C., Raboso-Gallego J., Aleman-Arteaga S., Buhles A., Sterker D.[...], Sanchez-Garcia I.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 97489PubMedEurope PMCCancer Res 82:1098-1109 (2022)Mapped to18
Characterization of a novel Lbx1 mouse loss of function strain.Decourtye L., McCallum-Loudeac J.A., Zellhuber-McMillan S., Young E., Sircombe K.J., Wilson M.J.View abstractCategoriesFunction, ExpressionSourceMGI: 97489PubMedEurope PMCDifferentiation 123:30-41 (2022)Mapped to99+
Pax5 Negatively Regulates Osteoclastogenesis through Downregulation of Blimp1.Yu J., Kim S., Lee N., Jeon H., Lee J., Takami M., Rho J.View abstractCategoriesFunction, ExpressionSourceMGI: 97489PubMedEurope PMCInt J Mol Sci 22:2097-2097 (2021)Mapped to21
EBF1 and PAX5 control pro-B cell expansion via opposing regulation of the Myc gene.Somasundaram R., Jensen C.T., Tingvall-Gustafsson J., Ahsberg J., Okuyama K., Prasad M., Hagman J.R., Wang X., Soneji S.[...], Sigvardsson M.View abstractCategoryFunctionSourceMGI: 97489PubMedEurope PMCBlood 137:3037-3049 (2021)Mapped to36