G3LS55 · G3LS55_9BRAS

  • Protein
    E3 ubiquitin-protein ligase listerin
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

E3 ubiquitin-protein ligase. Component of the ribosome quality control complex (RQC), a ribosome-associated complex that mediates ubiquitination and extraction of incompletely synthesized nascent chains for proteasomal degradation.

Catalytic activity

  • S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N6-ubiquitinyl-[acceptor protein]-L-lysine.
    EC:2.3.2.27 (UniProtKB | ENZYME | Rhea)

Pathway

Protein modification; protein ubiquitination.

GO annotations

all annotationsall molecular functionnucleotide bindingmolecular_functionnucleic acid bindingdna bindingchromatin bindingdna-binding transcription factor activityrna bindingcytoskeletal motor activitycatalytic activitynuclease activitysignaling receptor bindingstructural molecule activitytransporter activitybindingprotein bindingtranslation factor activity, rna bindinglipid bindingkinase activitytransferase activityhydrolase activityoxygen bindingenzyme regulator activitycarbohydrate bindingsignaling receptor activitytranslation regulator activitytranscription regulator activityother molecular functionall biological processcarbohydrate metabolic processgeneration of precursor metabolites and energynucleobase-containing compound metabolic processdna metabolic processtranslationlipid metabolic processtransportresponse to stresscell cyclecell communicationsignal transductioncell-cell signalingmulticellular organism developmentcircadian rhythmbiological_processmetabolic processcatabolic processbiosynthetic processresponse to light stimulusresponse to external stimulustropismresponse to biotic stimulusresponse to abiotic stimulusresponse to endogenous stimulusembryo developmentpost-embryonic developmentfruit ripeningabscissionpollinationflower developmentcellular processprogrammed cell deathphotosynthesiscellular component organizationcell growthprotein metabolic processcellular homeostasissecondary metabolic processreproductive processcell differentiationprotein modification processgrowthepigenetic regulation of gene expressionresponse to chemicalanatomical structure developmentregulation of molecular functionother biological processall cellular componentcellular_componentextracellular regioncell wallintracellular anatomical structurenucleusnuclear envelopenucleoplasmnucleoluscytoplasmmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuscytosolribosomecytoskeletonplasma membranechloroplastplastidthylakoidmembraneexternal encapsulating structureother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentcytosol
Cellular ComponentRQC complex
Molecular Functionmetal ion binding
Molecular Functionribosomal large subunit binding
Molecular Functionubiquitin protein ligase activity
Biological Processprotein ubiquitination
Biological Processrescue of stalled ribosome
Biological Processribosome-associated ubiquitin-dependent protein catabolic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    E3 ubiquitin-protein ligase listerin
  • EC number
  • Alternative names
    • RING-type E3 ubiquitin transferase listerin

Organism names

  • Taxonomic identifier
  • Organism
  • Strains
    • Cr1209_26_TS4
    • Cr1215_17_TS1
    • Cr39_1_TS1
    • Cr50_1_TS1
  • Taxonomic lineage
    Eukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > rosids > malvids > Brassicales > Brassicaceae > Camelineae > Capsella

Accessions

  • Primary accession
    G3LS55

Subcellular Location

Interaction

Subunit

Component of the ribosome quality control complex (RQC).

Family & Domains

Sequence similarities

Belongs to the LTN1 family.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Fragment
  • Length
    161
  • Mass (Da)
    17,957
  • Last updated
    2011-11-16 v1
  • Checksum
    61A8E07404294BC8
LQRHVSNEERTLLLDLFRKQKQDPVASSVVTQLPAVQILLARLIVIAVSYCGNDFNEDDWDFVFSNLKRLIQSAVVVMEETSENVNDFISGVSSVEKENDTLEGLGHIVFISDPSISNAQNALSAFSLLNALVKHKSTEGEDNLKSLADETWDPVKDRILE

Features

Showing features for non-terminal residue.

TypeIDPosition(s)Description
Non-terminal residue1
Non-terminal residue161

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
JN406164
EMBL· GenBank· DDBJ
AEN83397.1
EMBL· GenBank· DDBJ
Genomic DNA
JN406165
EMBL· GenBank· DDBJ
AEN83398.1
EMBL· GenBank· DDBJ
Genomic DNA
JN406166
EMBL· GenBank· DDBJ
AEN83399.1
EMBL· GenBank· DDBJ
Genomic DNA
JN406167
EMBL· GenBank· DDBJ
AEN83400.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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