G3HG81 · G3HG81_CRIGR
- ProteinAmmonium transporter Rh type B
- GeneRhbg
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids455 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
Catalytic activity
- CO2(out) = CO2(in)This reaction proceeds in the forward direction.
- NH4+(in) = NH4+(out)This reaction proceeds in the forward and the backward directions.
- methylamine(out) = methylamine(in)This reaction proceeds in the forward direction.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | basolateral plasma membrane | |
Cellular Component | lateral plasma membrane | |
Cellular Component | spectrin-associated cytoskeleton | |
Molecular Function | ammonium channel activity | |
Molecular Function | ankyrin binding | |
Molecular Function | carbon dioxide transmembrane transporter activity | |
Biological Process | transepithelial ammonium transport |
Names & Taxonomy
Protein names
- Recommended nameAmmonium transporter Rh type B
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Glires > Rodentia > Myomorpha > Muroidea > Cricetidae > Cricetinae > Cricetulus
Accessions
- Primary accessionG3HG81
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Basolateral cell membrane ; Multi-pass membrane protein
Cell membrane ; Multi-pass membrane protein
Lateral cell membrane ; Multi-pass membrane protein
Membrane ; Multi-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Transmembrane | 64-82 | Helical | ||||
Sequence: VHAMVFVGFGFLMVFLQRY | ||||||
Transmembrane | 89-111 | Helical | ||||
Sequence: FTFLVATFTLQWATLVQGFLHSF | ||||||
Transmembrane | 123-142 | Helical | ||||
Sequence: LINADFCAGAVLISFGAVLG | ||||||
Transmembrane | 149-168 | Helical | ||||
Sequence: LLLMALLETVLFSVNEFILL | ||||||
Transmembrane | 180-198 | Helical | ||||
Sequence: MTIHTFGAYFGLFLSRILY | ||||||
Transmembrane | 210-230 | Helical | ||||
Sequence: SSVYHSDLFAVIGTIFLWIFW | ||||||
Transmembrane | 250-269 | Helical | ||||
Sequence: NTYYSLTASTLSTFALSALV | ||||||
Transmembrane | 302-322 | Helical | ||||
Sequence: FGAVAAGFLAGTVSTLGYKFF | ||||||
Transmembrane | 342-360 | Helical | ||||
Sequence: HGMPGVLGALLGVLVAWLA | ||||||
Transmembrane | 391-412 | Helical | ||||
Sequence: LFGMFVTLVFASVGGSLGGLLL |
Keywords
- Cellular component
PTM/Processing
Features
Showing features for signal, chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Signal | 1-24 | |||||
Sequence: MARTPRHRRLVLPLLCLLFQGATA | ||||||
Chain | PRO_5042453665 | 25-455 | Ammonium transporter Rh type B | |||
Sequence: LLFAVFVRYNHETDAALWHWGNHSNVDNEFYFRYPSFQDVHAMVFVGFGFLMVFLQRYGFSSVGFTFLVATFTLQWATLVQGFLHSFHGGHIHVGLESLINADFCAGAVLISFGAVLGKTGPAQLLLMALLETVLFSVNEFILLRLLGVRDAGGSMTIHTFGAYFGLFLSRILYRSQLEKSRQRQSSVYHSDLFAVIGTIFLWIFWPSFNSAPTALGDGQHRTALNTYYSLTASTLSTFALSALVSRDGRLDMVHIQNAALAGGVVVGTSSEMMLTPFGAVAAGFLAGTVSTLGYKFFTPVLESRFKVQDTCGVHNLHGMPGVLGALLGVLVAWLATHEVYGDGLQNVFPLIAQGQRSATSQAVYQLFGMFVTLVFASVGGSLGGLLLKLPFLDSPPDSQCFEDQIYWEVPGEQEAEAQRPLRAEEPDTQA |
Keywords
- PTM
Proteomic databases
Interaction
Subunit
Interacts (via C-terminus) with ANK2 and ANK3; required for targeting to the basolateral membrane.
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 23-414 | Ammonium transporter AmtB-like | ||||
Sequence: TALLFAVFVRYNHETDAALWHWGNHSNVDNEFYFRYPSFQDVHAMVFVGFGFLMVFLQRYGFSSVGFTFLVATFTLQWATLVQGFLHSFHGGHIHVGLESLINADFCAGAVLISFGAVLGKTGPAQLLLMALLETVLFSVNEFILLRLLGVRDAGGSMTIHTFGAYFGLFLSRILYRSQLEKSRQRQSSVYHSDLFAVIGTIFLWIFWPSFNSAPTALGDGQHRTALNTYYSLTASTLSTFALSALVSRDGRLDMVHIQNAALAGGVVVGTSSEMMLTPFGAVAAGFLAGTVSTLGYKFFTPVLESRFKVQDTCGVHNLHGMPGVLGALLGVLVAWLATHEVYGDGLQNVFPLIAQGQRSATSQAVYQLFGMFVTLVFASVGGSLGGLLLKL |
Sequence similarities
Belongs to the ammonium transporter (TC 2.A.49) family. Rh subfamily.
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length455
- Mass (Da)49,865
- Last updated2011-11-16 v1
- Checksum56234401328248D0
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
JH000344 EMBL· GenBank· DDBJ | EGW07052.1 EMBL· GenBank· DDBJ | Genomic DNA |