G3H6T7 · G3H6T7_CRIGR
- ProteinATP-dependent RNA helicase SUPV3L1, mitochondrial
- GeneSupv3l1
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids779 (go to sequence)
- Protein existenceInferred from homology
- Annotation score4/5
Function
Catalytic activity
- ATP + H2O = ADP + phosphate + H+
Cofactor
Protein has several cofactor binding sites:
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | mitochondrial degradosome | |
Cellular Component | mitochondrial nucleoid | |
Cellular Component | nucleus | |
Molecular Function | 3'-5' RNA helicase activity | |
Molecular Function | ATP binding | |
Molecular Function | DNA binding | |
Molecular Function | DNA helicase activity | |
Molecular Function | double-stranded RNA binding | |
Molecular Function | hydrolase activity, acting on acid anhydrides | |
Molecular Function | protein homodimerization activity | |
Biological Process | DNA recombination | |
Biological Process | mitochondrial mRNA surveillance | |
Biological Process | mitochondrial ncRNA surveillance | |
Biological Process | mitochondrial RNA 3'-end processing | |
Biological Process | mitochondrion organization | |
Biological Process | negative regulation of apoptotic process | |
Biological Process | positive regulation of cell growth | |
Biological Process | positive regulation of mitochondrial RNA catabolic process |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameATP-dependent RNA helicase SUPV3L1, mitochondrial
- EC number
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Glires > Rodentia > Myomorpha > Muroidea > Cricetidae > Cricetinae > Cricetulus
Accessions
- Primary accessionG3H6T7
Proteomes
Subcellular Location
PTM/Processing
Features
Showing features for signal, chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Signal | 1-18 | |||||
Sequence: MSLPRCVLLWARLPAGLG | ||||||
Chain | PRO_5042805146 | 19-779 | ATP-dependent RNA helicase SUPV3L1, mitochondrial | |||
Sequence: AGSRAATCSALRASVGSFPGAPGRVPCLAASSSASGGSKAPNTSLFVPLTVKPQGPSADGDVGAELTRPLDKNEVKKILDKFYKRQEIQKLSADYGLDARLFHQAFISFRNYIMQSHSLDVDIHIVLNDICFSAAHVDDLFPFFLRHAKQIFPVLECKEDLRKISDLRIPPNWYPEARAIRRKIVFHSGPTNSGKTYHAIQRYLSAKSGVYCGPLKLLAHEIFEKSNAAGVPCDLVTGEERQTVEAEGKQATHVSCTVEMCSVTTPYEVAVIDEIQMIRDLGRGWAWTRALLGLCAEEVHLCGESAAIDLVTELLYTTGEEVEVHKYERLTPISVLDHALESLDNLRPGDCIVCFSKNDIYSVSRQIEIRGLESAVIYGSLPPGTKLAQARKFNDPSDPCKILVATDAIGMGLNLSIRRIIFYSLIKPSINEKGEKELEPITTSQALQIAGRAGRFSSHFKEGEVTTMYREDLALLKEILNRAVDPIQAAGLHPTAEQIEMFAYHLPETTLSNLIDIFVDFAQVDGQYFVCNMDDFKFSAELIQHIPLSLRVRYVFCTAPINKKQPFVCSSLLQFARQYSRNEPLTFAWLRRYIKWPLLPPKNIKDLMDLEAVHDVFDLYLWLSYRFIDMFPDSNLVRGLQKELDAIIQDGVHNITKLIKISESRKLLNLESLPLGNQSHLSGTLKSGAKRTRGTKSAGGKAAEPLSPSAKELPLASRLVQQGLLTADMLKQLQKEWLTQQPELGREKAGTRRKKKDPSSD |
Proteomic databases
Interaction
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for domain, region, compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 353-518 | Helicase C-terminal | ||||
Sequence: VLDHALESLDNLRPGDCIVCFSKNDIYSVSRQIEIRGLESAVIYGSLPPGTKLAQARKFNDPSDPCKILVATDAIGMGLNLSIRRIIFYSLIKPSINEKGEKELEPITTSQALQIAGRAGRFSSHFKEGEVTTMYREDLALLKEILNRAVDPIQAAGLHPTAEQIE | ||||||
Region | 699-726 | Disordered | ||||
Sequence: LSGTLKSGAKRTRGTKSAGGKAAEPLSP | ||||||
Region | 755-779 | Disordered | ||||
Sequence: WLTQQPELGREKAGTRRKKKDPSSD | ||||||
Compositional bias | 764-779 | Basic and acidic residues | ||||
Sequence: REKAGTRRKKKDPSSD |
Sequence similarities
Belongs to the helicase family.
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length779
- Mass (Da)86,706
- Last updated2011-11-16 v1
- Checksum26970C61FDFCFF0E
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 764-779 | Basic and acidic residues | ||||
Sequence: REKAGTRRKKKDPSSD |
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
JH000180 EMBL· GenBank· DDBJ | EGV93785.1 EMBL· GenBank· DDBJ | Genomic DNA |