G3H6T7 · G3H6T7_CRIGR
- ProteinATP-dependent RNA helicase SUPV3L1, mitochondrial
- GeneSupv3l1
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids779 (go to sequence)
- Protein existenceInferred from homology
- Annotation score4/5
Function
Catalytic activity
- ATP + H2O = ADP + H+ + phosphate
Cofactor
Protein has several cofactor binding sites:
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | mitochondrial degradosome | |
Cellular Component | mitochondrial nucleoid | |
Cellular Component | nucleus | |
Molecular Function | 3'-5' RNA helicase activity | |
Molecular Function | ATP binding | |
Molecular Function | DNA binding | |
Molecular Function | DNA helicase activity | |
Molecular Function | double-stranded RNA binding | |
Molecular Function | hydrolase activity, acting on acid anhydrides | |
Molecular Function | protein homodimerization activity | |
Biological Process | DNA recombination | |
Biological Process | mitochondrial mRNA surveillance | |
Biological Process | mitochondrial ncRNA surveillance | |
Biological Process | mitochondrial RNA 3'-end processing | |
Biological Process | mitochondrion organization | |
Biological Process | negative regulation of apoptotic process | |
Biological Process | positive regulation of cell growth | |
Biological Process | positive regulation of mitochondrial RNA catabolic process |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameATP-dependent RNA helicase SUPV3L1, mitochondrial
- EC number
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Glires > Rodentia > Myomorpha > Muroidea > Cricetidae > Cricetinae > Cricetulus
Accessions
- Primary accessionG3H6T7
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Keywords
- Cellular component
PTM/Processing
Features
Showing features for signal, chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Signal | 1-18 | |||||
Sequence: MSLPRCVLLWARLPAGLG | ||||||
Chain | PRO_5042453608 | 19-779 | ATP-dependent RNA helicase SUPV3L1, mitochondrial | |||
Sequence: AGSRAATCSALRASVGSFPGAPGRVPCLAASSSASGGSKAPNTSLFVPLTVKPQGPSADGDVGAELTRPLDKNEVKKILDKFYKRQEIQKLSADYGLDARLFHQAFISFRNYIMQSHSLDVDIHIVLNDICFSAAHVDDLFPFFLRHAKQIFPVLECKEDLRKISDLRIPPNWYPEARAIRRKIVFHSGPTNSGKTYHAIQRYLSAKSGVYCGPLKLLAHEIFEKSNAAGVPCDLVTGEERQTVEAEGKQATHVSCTVEMCSVTTPYEVAVIDEIQMIRDLGRGWAWTRALLGLCAEEVHLCGESAAIDLVTELLYTTGEEVEVHKYERLTPISVLDHALESLDNLRPGDCIVCFSKNDIYSVSRQIEIRGLESAVIYGSLPPGTKLAQARKFNDPSDPCKILVATDAIGMGLNLSIRRIIFYSLIKPSINEKGEKELEPITTSQALQIAGRAGRFSSHFKEGEVTTMYREDLALLKEILNRAVDPIQAAGLHPTAEQIEMFAYHLPETTLSNLIDIFVDFAQVDGQYFVCNMDDFKFSAELIQHIPLSLRVRYVFCTAPINKKQPFVCSSLLQFARQYSRNEPLTFAWLRRYIKWPLLPPKNIKDLMDLEAVHDVFDLYLWLSYRFIDMFPDSNLVRGLQKELDAIIQDGVHNITKLIKISESRKLLNLESLPLGNQSHLSGTLKSGAKRTRGTKSAGGKAAEPLSPSAKELPLASRLVQQGLLTADMLKQLQKEWLTQQPELGREKAGTRRKKKDPSSD |
Proteomic databases
Interaction
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for domain, region, compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 353-518 | Helicase C-terminal | ||||
Sequence: VLDHALESLDNLRPGDCIVCFSKNDIYSVSRQIEIRGLESAVIYGSLPPGTKLAQARKFNDPSDPCKILVATDAIGMGLNLSIRRIIFYSLIKPSINEKGEKELEPITTSQALQIAGRAGRFSSHFKEGEVTTMYREDLALLKEILNRAVDPIQAAGLHPTAEQIE | ||||||
Region | 699-726 | Disordered | ||||
Sequence: LSGTLKSGAKRTRGTKSAGGKAAEPLSP | ||||||
Region | 755-779 | Disordered | ||||
Sequence: WLTQQPELGREKAGTRRKKKDPSSD | ||||||
Compositional bias | 764-779 | Basic and acidic residues | ||||
Sequence: REKAGTRRKKKDPSSD |
Sequence similarities
Belongs to the helicase family.
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length779
- Mass (Da)86,706
- Last updated2011-11-16 v1
- Checksum26970C61FDFCFF0E
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 764-779 | Basic and acidic residues | ||||
Sequence: REKAGTRRKKKDPSSD |
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
JH000180 EMBL· GenBank· DDBJ | EGV93785.1 EMBL· GenBank· DDBJ | Genomic DNA |