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G2GWI3 · G2GWI3_9ENTR

Function

function

Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Pathway

Pyrimidine metabolism; UMP biosynthesis via de novo pathway; UMP from orotate: step 2/2.

Features

Showing features for binding site, active site.

Type
IDPosition(s)Description
Binding site21substrate
Binding site43substrate
Active site70For OMPdecase activity
Binding site70-79substrate
Active site72For OMPdecase activity
Active site72Proton donor
Active site75For OMPdecase activity
Binding site130substrate
Binding site191substrate
Binding site200substrate
Binding site220substrate
Binding site221substrate

GO annotations

AspectTerm
Cellular Componentcytosol
Molecular Functionorotidine-5'-phosphate decarboxylase activity
Biological Process'de novo' pyrimidine nucleobase biosynthetic process
Biological Process'de novo' UMP biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Orotidine 5'-phosphate decarboxylase
  • EC number
  • Alternative names
    • OMP decarboxylase
      (OMPDCase
      ; OMPdecase
      )

Gene names

    • Name
      pyrF
    • ORF names
      Rin_00001190

Organism names

  • Taxonomic identifier
  • Strain
    • R5.15
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Gammaproteobacteria > Enterobacterales > Enterobacteriaceae > aphid secondary symbionts > Candidatus Regiella

Accessions

  • Primary accession
    G2GWI3

Proteomes

Subcellular Location

Interaction

Subunit

Homodimer.

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain15-236Orotidine 5'-phosphate decarboxylase

Sequence similarities

Belongs to the OMP decarboxylase family. Type 1 subfamily.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    242
  • Mass (Da)
    25,971
  • Last updated
    2011-11-16 v1
  • MD5 Checksum
    CD916079E34798443C22114578CCEEE2
MRVKIENDMSANASPIIVALDYADINDALAFVDRISPQDCRLKVGKEMFTSQGPQWITKLQDRGFDIFLDVKFHDIPHTTAQAVKAAADLGVWMVNVHAVGGEKMLVAAKEALSNFGKKAPLLIAVTVLTSMDEDDLSAVGIDDCVNDQVERLAKLSRNCGLDGVVCSGREAAHLKNCCGTAFKLVTPGIRPVGSVVGDQQRVMTPKQALDAGADFLVIGRPITESKEPAKALKAIRDSLVA

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AGCA01000032
EMBL· GenBank· DDBJ
EGY29883.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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