G1TY34 · G1TY34_RABIT

Function

Features

Showing features for binding site.

110311002003004005006007008009001,000
TypeIDPosition(s)Description
Binding site314Ca2+ 1 (UniProtKB | ChEBI)
Binding site316Ca2+ 1 (UniProtKB | ChEBI)
Binding site318Ca2+ 1 (UniProtKB | ChEBI)
Binding site320Ca2+ 1 (UniProtKB | ChEBI)
Binding site322Ca2+ 1 (UniProtKB | ChEBI)
Binding site377Ca2+ 2 (UniProtKB | ChEBI)
Binding site379Ca2+ 2 (UniProtKB | ChEBI)
Binding site381Ca2+ 2 (UniProtKB | ChEBI)
Binding site383Ca2+ 2 (UniProtKB | ChEBI)
Binding site385Ca2+ 2 (UniProtKB | ChEBI)
Binding site439Ca2+ 3 (UniProtKB | ChEBI)
Binding site441Ca2+ 3 (UniProtKB | ChEBI)
Binding site443Ca2+ 3 (UniProtKB | ChEBI)
Binding site445Ca2+ 3 (UniProtKB | ChEBI)
Binding site447Ca2+ 3 (UniProtKB | ChEBI)

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentexternal side of plasma membrane
Cellular Componentintegrin alpha4-beta1 complex
Cellular Componentintegrin alpha4-beta7 complex
Molecular FunctionC-X3-C chemokine binding
Molecular Functionintegrin binding
Molecular Functionmetal ion binding
Biological Processcell-cell adhesion mediated by integrin
Biological Processcell-matrix adhesion involved in ameboidal cell migration
Biological Processcellular response to amyloid-beta
Biological Processendodermal cell differentiation
Biological Processheterotypic cell-cell adhesion
Biological Processintegrin-mediated signaling pathway
Biological Processleukocyte tethering or rolling
Biological Processnegative regulation of protein homodimerization activity
Biological Processnegative regulation of vasoconstriction
Biological Processpositive regulation of endothelial cell apoptotic process
Biological Processpositive regulation of vascular endothelial cell proliferation
Biological Processreceptor clustering
Biological Processsubstrate adhesion-dependent cell spreading

Keywords

Names & Taxonomy

Protein names

  • Submitted names
    • Integrin subunit alpha 4

Gene names

    • Name
      ITGA4

Organism names

  • Taxonomic identifier
  • Strain
    • Thorbecke inbred
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Glires > Lagomorpha > Leporidae > Oryctolagus

Accessions

  • Primary accession
    G1TY34

Proteomes

Subcellular Location

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane976-1000Helical

Keywords

  • Cellular component

PTM/Processing

Features

Showing features for signal, chain, glycosylation, disulfide bond.

TypeIDPosition(s)Description
Signal1-33
ChainPRO_500142455534-1031
Glycosylation79N-acetyl-D-glucosamine 1
Glycosylation79N-linked (GlcNAc...) asparagine
Disulfide bond91↔101
Disulfide bond114↔118
Glycosylation122N-acetyl-D-glucosamine 1
Glycosylation137N-acetyl-D-glucosamine 2
Glycosylation138N-acetyl-D-glucosamine 2
Glycosylation138N-linked (GlcNAc...) asparagine
Disulfide bond144↔165
Disulfide bond183↔198
Disulfide bond486↔495
Disulfide bond501↔557
Glycosylation518N-acetyl-D-glucosamine 3
Glycosylation518N-linked (GlcNAc...) asparagine
Glycosylation538N-acetyl-D-glucosamine 4
Glycosylation538N-linked (GlcNAc...) asparagine
Glycosylation541N-acetyl-D-glucosamine 4
Glycosylation545N-acetyl-D-glucosamine 4

Keywords

Proteomic databases

PTM databases

Expression

Gene expression databases

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for repeat, domain.

TypeIDPosition(s)Description
Repeat35-100FG-GAP
Repeat292-351FG-GAP
Repeat355-412FG-GAP
Repeat416-478FG-GAP
Domain463-620Integrin alpha first immunoglubulin-like
Domain622-769Integrin alpha second immunoglobulin-like
Domain779-957Integrin alpha third immunoglobulin-like

Sequence similarities

Belongs to the integrin alpha chain family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    1,031
  • Mass (Da)
    114,656
  • Last updated
    2011-10-19 v1
  • Checksum
    961852B4D3F20116
MAGEARRGSGSRGAAVREAVMLLLCLGIPTGRPYNLDTESALLYQGPPGTLFGYSVALHSHGSNRWLIVGAPTANWLANASVVSPGAIYRCRIGQNPGQTCEQLQLGSPTGEPCGKTCLEERDNEWLGVTLSRQPGENGSIVTCGHRWKNIFYIKNENKLPIGVCYGMPSDLRTELSKRMAPCYQDYIRKFGENFASCQAGISSFYTEDLIVMGAPGSFYWTGSLFVYNITTNKYKAFWDKDNQVKFGSYLGYSVGAGHFWSRHTTEVVGGAPQHEQIGKAYIFSIDARELNILYEMKGKKLGSYFGASVCAVDLNADGFSDLLVGAPMQSTIREEGRVFVYINSGSGAVMNEMETELIGSDKYAARFGESIVNLGDIDNDGFEDVAIGAPQEDDLRGAIYIYNGRADGISPTFSQRIEGLQVSKSLSMFGQSISGQIDADNNGYVDVAVGAFRSNSAVLLRTRPVVIVDASLRHPEAVNRTKFDCIENGLPSVCIDLKLCFSYKGKEVPGYIVLFYNMSLDVNRKAESPSRFYFSSNGTSDVITGSIQVSSKATNCRTHQAFMRKDVRDILTPVQIEAAYRLGQHVLTKRSAEEFPPLQPILQQKKEKDVIKKMINFARFCAHENCTADLQVSAKIGFLKPHENKTYLAVGGMKMLMLNVSLFNAGDDAYGTTLHIRLPMGLYFIKILDLEEKQINCEVTESSGPVKLDCSVGYIYVDHLSRIDISFLLDVSSLSRAEEDVNITVHATCENEGEMDTLKHNKVTLAIPLRYEVMLTAHGFVNPTSFVYGSSEENDHETCMTEKMNLTFHVINTGNSMAPNVSMEIMVPNSFMPQTNKLFNILDVQMTTGECFFETYQRECALEQPKGAMETLKGIFTFLSKTDKRLLYCIKADPHCLNVLCNFGKMESGKEASVHIQLEGRPSILEMDETSSLKFEIRATAFPEPHPKVVELNKEENVAHVLLEGLHHQRPKRHFTIVIISSSLLLGLIVLLLISYVMWKAGFFKRQYKSILQEENRRDSWSYVKSNNDN

Computationally mapped potential isoform sequences

There is 1 potential isoform mapped to this entry

View all
EntryEntry nameGene nameLength
A0A5F9DBS0A0A5F9DBS0_RABITITGA41016

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AAGW02003809
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.
AAGW02003810
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.
AAGW02003811
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.
AAGW02003812
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.

Genome annotation databases

Similar Proteins

Disclaimer

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