A high-resolution map of human evolutionary constraint using 29 mammals.Lindblad-Toh K., Garber M., Zuk O., Lin M.F., Parker B.J., Washietl S., Kheradpour P., Ernst J., Jordan G.[...], Kellis M.View abstractCited forNUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]StrainThorbeckeCategoriesSequencesSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCNature 478:476-482 (2011)Cited in99+99+
The initiation of mammalian protein synthesis and mRNA scanning mechanism.Lomakin I.B., Steitz T.A.View abstractCited forX-RAY CRYSTALLOGRAPHY (7.01 ANGSTROMS) OF 40S RIBOSOME, FUNCTION, SUBUNIT, SUBCELLULAR LOCATIONCategoriesFunction, Interaction, Structure, Subcellular LocationSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCNature 500:307-311 (2013)Cited in314Mapped to2
Cryo-EM of ribosomal 80S complexes with termination factors reveals the translocated cricket paralysis virus IRES.Muhs M., Hilal T., Mielke T., Skabkin M.A., Sanbonmatsu K.Y., Pestova T.V., Spahn C.M.View abstractCited forSTRUCTURE BY ELECTRON MICROSCOPY (9.00 ANGSTROMS) OF RIBOSOME, FUNCTION, SUBUNIT, SUBCELLULAR LOCATIONCategoriesFunction, Interaction, Structure, Subcellular LocationSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCMol. Cell 57:422-432 (2015)Cited in331Mapped to4
Structural basis for stop codon recognition in eukaryotes.Brown A., Shao S., Murray J., Hegde R.S., Ramakrishnan V.View abstractCited forSTRUCTURE BY ELECTRON MICROSCOPY (3.45 ANGSTROMS) OF 2-130 OF RIBOSOME, FUNCTION, SUBCELLULAR LOCATION, SUBUNITCategoriesFunction, Interaction, Structure, Subcellular LocationSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCNature 524:493-496 (2015)Cited in634Mapped to1
Decoding mammalian ribosome-mRNA states by translational GTPase complexes.Shao S., Murray J., Brown A., Taunton J., Ramakrishnan V., Hegde R.S.View abstractCited forSTRUCTURE BY ELECTRON MICROSCOPY (3.31 ANGSTROMS) OF RIBOSOME, FUNCTION, SUBCELLULAR LOCATION, SUBUNITCategoriesFunction, Interaction, Structure, Subcellular LocationSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCCell 167:1229-1240 (2016)Cited in675Mapped to2
tRNA translocation by the eukaryotic 80S ribosome and the impact of GTP hydrolysis.Flis J., Holm M., Rundlet E.J., Loerke J., Hilal T., Dabrowski M., Burger J., Mielke T., Blanchard S.C.[...], Budkevich T.V.View abstractCited forSTRUCTURE BY ELECTRON MICROSCOPY (3.60 ANGSTROMS) OF 2-130 OF RIBOSOME, FUNCTION, SUBCELLULAR LOCATION, SUBUNITCategoriesFunction, Interaction, Structure, Subcellular LocationSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCCell Rep. 25:2676-2688 (2018)Cited in361
Dual tRNA mimicry in the Cricket paralysis virus IRES uncovers an unexpected similarity with the Hepatitis C Virus IRES.Pisareva V.P., Pisarev A.V., Fernandez I.S.View abstractCited forSTRUCTURE BY ELECTRON MICROSCOPY (3.20 ANGSTROMS) OF RIBOSOME, SUBCELLULAR LOCATION, SUBUNITCategoriesInteraction, Structure, Subcellular LocationSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCElife 7:0-0 (2018)Cited in736Mapped to2
Structures of translationally inactive mammalian ribosomes.Brown A., Baird M.R., Yip M.C., Murray J., Shao S.View abstractCited forSTRUCTURE BY ELECTRON MICROSCOPY (3.30 ANGSTROMS) OF 2-130 OF RIBOSOME, SUBCELLULAR LOCATION, SUBUNITCategoriesInteraction, Structure, Subcellular LocationSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCElife 7:e40486-e40486 (2018)Cited in553Mapped to17
ZNF598 is a quality control sensor of collided ribosomes.Juszkiewicz S., Chandrasekaran V., Lin Z., Kraatz S., Ramakrishnan V., Hegde R.S.View abstractCited forSTRUCTURE BY ELECTRON MICROSCOPY (3.80 ANGSTROMS) OF RIBOSOME, SUBCELLULAR LOCATION, SUBUNITCategoriesInteraction, Structure, Subcellular LocationSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCMol. Cell 72:469-481 (2018)Cited in554
Structural and mutational analysis of the ribosome-arresting human XBP1u.Shanmuganathan V., Schiller N., Magoulopoulou A., Cheng J., Braunger K., Cymer F., Berninghausen O., Beatrix B., Kohno K.[...], Beckmann R.View abstractCited forSTRUCTURE BY ELECTRON MICROSCOPY (3.00 ANGSTROMS) OF 2-130 OF RIBOSOME, SUBCELLULAR LOCATION, SUBUNITCategoriesInteraction, Structure, Subcellular LocationSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCElife 8:0-0 (2019)Cited in654Mapped to8
The Israeli acute paralysis virus IRES captures host ribosomes by mimicking a ribosomal state with hybrid tRNAs.Acosta-Reyes F., Neupane R., Frank J., Fernandez I.S.View abstractCited forSTRUCTURE BY ELECTRON MICROSCOPY (3.10 ANGSTROMS) OF RIBOSOME, SUBUNIT, SUBCELLULAR LOCATIONCategoriesInteraction, Structure, Subcellular LocationSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCEMBO J. 38:e102226-e102226 (2019)Cited in704
Mechanism of ribosome stalling during translation of a poly(A) tail.Chandrasekaran V., Juszkiewicz S., Choi J., Puglisi J.D., Brown A., Shao S., Ramakrishnan V., Hegde R.S.View abstractCited forSTRUCTURE BY ELECTRON MICROSCOPY (2.80 ANGSTROMS) OF RIBOSOME, SUBCELLULAR LOCATION, SUBUNITCategoriesInteraction, Structure, Subcellular LocationSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCNat. Struct. Mol. Biol. 26:1132-1140 (2019)Cited in603
The Halastavi arva virus intergenic region IRES promotes translation by the simplest possible initiation mechanism.Abaeva I.S., Vicens Q., Bochler A., Soufari H., Simonetti A., Pestova T.V., Hashem Y., Hellen C.U.T.View abstractCited forSTRUCTURE BY ELECTRON MICROSCOPY (3.49 ANGSTROMS) OF RIBOSOME, SUBCELLULAR LOCATION, SUBUNITCategoriesInteraction, Structure, Subcellular LocationSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCCell Rep. 33:108476-108476 (2020)Cited in637Mapped to9
A complex IRES at the 5'-UTR of a viral mRNA assembles a functional 48S complex via an uAUG intermediate.Neupane R., Pisareva V.P., Rodriguez C.F., Pisarev A.V., Fernandez I.S.View abstractCited forSTRUCTURE BY ELECTRON MICROSCOPY (3.00 ANGSTROMS) OF RIBOSOME, SUBUNIT, SUBCELLULAR LOCATIONCategoriesInteraction, Structure, Subcellular LocationSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCElife 9:0-0 (2020)Cited in3110Mapped to2
Molecular architecture of 40S translation initiation complexes on the hepatitis C virus IRES.Brown Z.P., Abaeva I.S., De S., Hellen C.U.T., Pestova T.V., Frank J.View abstractCited forSTRUCTURE BY ELECTRON MICROSCOPY (3.50 ANGSTROMS) OF RIBOSOME, SUBCELLULAR LOCATION, SUBUNITCategoriesInteraction, Structure, Subcellular LocationSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCEMBO J. 41:e110581-e110581 (2022)Cited in305Mapped to5
Direct epitranscriptomic regulation of mammalian translation initiation through N4-acetylcytidine.Arango D., Sturgill D., Yang R., Kanai T., Bauer P., Roy J., Wang Z., Hosogane M., Schiffers S., Oberdoerffer S.View abstractCited forSTRUCTURE BY ELECTRON MICROSCOPY (2.80 ANGSTROMS) OF RIBOSOME, SUBCELLULAR LOCATION, SUBUNITCategoriesInteraction, Structure, Subcellular LocationSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCMol. Cell 82:2797-2814 (2022)Cited in566Mapped to3
Structure of the mammalian ribosome as it decodes the selenocysteine UGA codon.Hilal T., Killam B.Y., Grozdanovic M., Dobosz-Bartoszek M., Loerke J., Buerger J., Mielke T., Copeland P.R., Simonovic M., Spahn C.M.T.View abstractCited forSTRUCTURE BY ELECTRON MICROSCOPY (2.80 ANGSTROMS) OF RIBOSOME, SUBCELLULAR LOCATION, SUBUNITCategoriesInteraction, Structure, Subcellular LocationSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCScience 376:1338-1343 (2022)Cited in4831Mapped to7
A molecular network of conserved factors keeps ribosomes dormant in the egg.Leesch F., Lorenzo-Orts L., Pribitzer C., Grishkovskaya I., Roehsner J., Chugunova A., Matzinger M., Roitinger E., Belacic K.[...], Pauli A.View abstractCited forSTRUCTURE BY ELECTRON MICROSCOPY (2.30 ANGSTROMS) OF RIBOSOME, SUBCELLULAR LOCATION, SUBUNITCategoriesInteraction, Structure, Subcellular LocationSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCNature 613:712-720 (2023)Cited in7999+Mapped to40
N<sup>6</sup>-methyladenosine in 5' UTR does not promote translation initiation.Guca E., Alarcon R., Palo M.Z., Santos L., Alonso-Gil S., Davyt M., de Lima L.H.F., Boissier F., Das S.[...], Ignatova Z.View abstractCategoriesStructureSourcePDB: 8P03, PDB: 8P09PubMedEurope PMCMol Cell 84:584-595.e6 (2024)Cited in8Mapped to28
The eRF1 degrader SRI-41315 acts as a molecular glue at the ribosomal decoding center.Coelho J.P.L., Yip M.C.J., Oltion K., Taunton J., Shao S.View abstractCategoriesStructureSourcePDB: 8SCBPubMedEurope PMCNat Chem Biol 20:877-884 (2024)Mapped to75
Modulation of GluA2-gamma5 synaptic complex desensitization, polyamine block and antiepileptic perampanel inhibition by auxiliary subunit cornichon-2.Gangwar S.P., Yen L.Y., Yelshanskaya M.V., Korman A., Jones D.R., Sobolevsky A.I.View abstractCategoriesStructureSourcePDB: 8BHFPubMedEurope PMCNat Struct Mol Biol 30:1481-1494 (2023)Cited in7Mapped to65
NAC controls cotranslational N-terminal methionine excision in eukaryotes.Gamerdinger M., Jia M., Schloemer R., Rabl L., Jaskolowski M., Khakzar K.M., Ulusoy Z., Wallisch A., Jomaa A.[...], Deuerling E.View abstractCategoriesStructureSourcePDB: 8P2KPubMedEurope PMCScience 380:1238-1243 (2023)Cited in12Mapped to77
Molecular basis of the TRAP complex function in ER protein biogenesis.Jaskolowski M., Jomaa A., Gamerdinger M., Shrestha S., Leibundgut M., Deuerling E., Ban N.View abstractCategoriesStructureSourcePDB: 8BTKPubMedEurope PMCNat Struct Mol Biol 30:770-777 (2023)Cited in11Mapped to80
Ribosome inhibition by C9ORF72-ALS/FTD-associated poly-PR and poly-GR proteins revealed by cryo-EM.Loveland A.B., Svidritskiy E., Susorov D., Lee S., Park A., Zvornicanin S., Demo G., Gao F.B., Korostelev A.A.View abstractCategoriesStructureSourcePDB: 7TOQ, PDB: 7TORPubMedEurope PMCNat Commun 13:2776-2776 (2022)Cited in8Mapped to99+
Discovery of C13-Aminobenzoyl Cycloheximide Derivatives that Potently Inhibit Translation Elongation.Koga Y., Hoang E.M., Park Y., Keszei A.F.A., Murray J., Shao S., Liau B.B.View abstractCategoriesStructureSourcePDB: 7MDZPubMedEurope PMCJ Am Chem Soc 143:13473-13477 (2021)Cited in5Mapped to71