G1PQN2 · G1PQN2_MYOLU
- ProteinEphrin type-B receptor 3
- GeneEPHB3
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids984 (go to sequence)
- Protein existencePredicted
- Annotation score4/5
Function
Catalytic activity
- L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H+
Features
Showing features for binding site, active site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 625-633 | ATP (UniProtKB | ChEBI) | |||
Binding site | 651 | ATP (UniProtKB | ChEBI) | |||
Active site | 744 | Proton acceptor | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | dendrite | |
Cellular Component | plasma membrane | |
Molecular Function | ATP binding | |
Molecular Function | axon guidance receptor activity | |
Molecular Function | transmembrane-ephrin receptor activity | |
Biological Process | angiogenesis | |
Biological Process | axonal fasciculation | |
Biological Process | cell migration | |
Biological Process | central nervous system projection neuron axonogenesis | |
Biological Process | corpus callosum development | |
Biological Process | dendritic spine morphogenesis | |
Biological Process | digestive tract morphogenesis | |
Biological Process | positive regulation of synapse assembly | |
Biological Process | protein autophosphorylation | |
Biological Process | regulation of axonogenesis | |
Biological Process | regulation of cell-cell adhesion | |
Biological Process | retinal ganglion cell axon guidance | |
Biological Process | roof of mouth development | |
Biological Process | substrate adhesion-dependent cell spreading | |
Biological Process | thymus development | |
Biological Process | urogenital system development |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameEphrin type-B receptor 3
- EC number
Gene names
Organism names
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Laurasiatheria > Chiroptera > Yangochiroptera > Vespertilionidae > Myotis
Accessions
- Primary accessionG1PQN2
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Cell membrane ; Single-pass type I membrane protein
Keywords
- Cellular component
PTM/Processing
Features
Showing features for disulfide bond.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Disulfide bond | 61↔179 | ||||
Disulfide bond | 96↔106 | ||||
Keywords
- PTM
Interaction
Subunit
Heterotetramer upon binding of the ligand. The heterotetramer is composed of an ephrin dimer and a receptor dimer. Oligomerization is probably required to induce biological responses.
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Domain | 19-197 | Eph LBD | |||
Domain | 319-434 | Fibronectin type-III | |||
Domain | 435-528 | Fibronectin type-III | |||
Domain | 619-882 | Protein kinase | |||
Domain | 911-975 | SAM | |||
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length984
- Mass (Da)108,718
- Last updated2011-10-19 v1
- MD5 Checksum3BC6DA8E6D6DE5BB64C861EE1980056D
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AAPE02008594 EMBL· GenBank· DDBJ | - | Genomic DNA | No translation available. | |
AAPE02008595 EMBL· GenBank· DDBJ | - | Genomic DNA | No translation available. |