G1PCQ3 · G1PCQ3_MYOLU
- ProteinSerine/threonine-protein kinase
- GenePRKD3
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids893 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
Catalytic activity
- L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H+
Cofactor
Activity regulation
Activated by DAG and phorbol esters.
Features
Showing features for binding site, active site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 583-591 | ATP (UniProtKB | ChEBI) | |||
Binding site | 608 | ATP (UniProtKB | ChEBI) | |||
Active site | 702 | Proton acceptor | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytosol | |
Cellular Component | nucleoplasm | |
Cellular Component | plasma membrane | |
Molecular Function | ATP binding | |
Molecular Function | diacylglycerol-dependent serine/threonine kinase activity | |
Molecular Function | metal ion binding | |
Biological Process | protein phosphorylation |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameSerine/threonine-protein kinase
- EC number
Gene names
Organism names
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Laurasiatheria > Chiroptera > Yangochiroptera > Vespertilionidae > Myotis
Accessions
- Primary accessionG1PCQ3
Proteomes
PTM/Processing
Keywords
- PTM
Interaction
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for domain, region, compositional bias.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Domain | 155-205 | Phorbol-ester/DAG-type | |||
Domain | 272-322 | Phorbol-ester/DAG-type | |||
Region | 333-367 | Disordered | |||
Compositional bias | 353-367 | Basic and acidic residues | |||
Domain | 417-533 | PH | |||
Domain | 577-835 | Protein kinase | |||
Sequence similarities
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length893
- Mass (Da)100,665
- Last updated2011-10-19 v1
- MD5 Checksum6BA2F5B870BECB29A64A8511DB3015EA
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Compositional bias | 353-367 | Basic and acidic residues | |||
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AAPE02005335 EMBL· GenBank· DDBJ | - | Genomic DNA | No translation available. | |
AAPE02005336 EMBL· GenBank· DDBJ | - | Genomic DNA | No translation available. | |
AAPE02005337 EMBL· GenBank· DDBJ | - | Genomic DNA | No translation available. |