G1P779 · G1P779_MYOLU

Function

Catalytic activity

Cofactor

biotin (UniProtKB | Rhea| CHEBI:57586 )

Pathway

Lipid metabolism; malonyl-CoA biosynthesis; malonyl-CoA from acetyl-CoA: step 1/1.

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentmitochondrion
Cellular Componentnucleus
Molecular Functionacetyl-CoA carboxylase activity
Molecular FunctionATP binding
Molecular Functionidentical protein binding
Molecular Functionmetal ion binding
Biological Processacetyl-CoA metabolic process
Biological Processenergy homeostasis
Biological Processfatty acid biosynthetic process
Biological Processmalonyl-CoA biosynthetic process
Biological Processnegative regulation of fatty acid beta-oxidation
Biological Processpositive regulation of heart growth
Biological Processpositive regulation of lipid storage
Biological Processprotein homotetramerization
Biological Processregulation of glucose metabolic process
Biological Processresponse to nutrient levels

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    acetyl-CoA carboxylase
  • EC number

Gene names

    • Name
      ACACB

Organism names

  • Taxonomic identifier
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Laurasiatheria > Chiroptera > Yangochiroptera > Vespertilionidae > Myotis

Accessions

  • Primary accession
    G1P779

Proteomes

Subcellular Location

PTM/Processing

Features

Showing features for signal, chain.

Type
IDPosition(s)Description
Signal1-16
ChainPRO_500341772517-2453acetyl-CoA carboxylase

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for region, compositional bias, domain.

Type
IDPosition(s)Description
Region29-149Disordered
Compositional bias33-68Polar residues
Compositional bias103-136Polar residues
Region162-187Disordered
Domain254-756Biotin carboxylation
Domain413-604ATP-grasp
Domain883-957Lipoyl-binding
Domain1690-2020CoA carboxyltransferase N-terminal
Domain2024-2340CoA carboxyltransferase C-terminal

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    2,453
  • Mass (Da)
    276,096
  • Last updated
    2011-10-19 v1
  • MD5 Checksum
    DF720217D39B859EA770FA12F1B27D08
MTLLLFLCCLILSCLTFSWLKIWGKMTDSKPVTKNKSEASFIPSQEPFAASNSSEEPPQKNGDRSSLPKTPNPAEPASPKGPKDADRQRTSRPPRHRNPSKSPLPSRDASPANGTRTQGLEAPDTNGLSSPARPQARARTLSKEDQKQAHIKRQLMTNFILGSFDDNSSDDEPGTGPGRDSSRKGSRASLGALTLEALRAAGDSETLVPAMSPAAGGPHFRRRPRWFKSVESHLIVHFNPKEQMCWTIYGGARSSRKVLIANNGIAAVKCMRSIRRWAYEMFRNERAIRFVVMVTPEDLKANAEYIKMADQYVPVPGGPNNNNYANVELIVDIAKRIPVQAVWAGWGHASENPKLPELLYKDDIAFLGPPSEAMWALGDKIASTIVAQTLQIPTLPWSGSGLTVAWAEEGLQEGKTISVPEDVYNRGCVKDIDEGLEAAERIGFPLMIKASEGGGGKGIRKAESAEDFPILFRQVQSEIPGSPVFLMKLAQHARHLEVQILADQYGNAVSLFGRDCSIQRRHQKIIEEAPATIATPVVFEFMEQCAVRLAKTVGYVSAGTVEYLYSQDGSFHFLELNPRLQVEHPCTEMIADVNLPAAQLQIAMGVPLHRLKDIRLLYGESPWGVTPIAFETPPNPPLARGHVIAARITSENPDEGFKPSSGTVQELNFRSSRNVWGYFSVAATGGLHEFADSQFGHCFSWGENREEAISNMVVALKELSIRGDFRTTVEYLINLLETESFQNNDIDTGWLDHLIAEKVQAEKPDIMLGVVCGALNVADAMFRTCMTDFLHSLERGQVLPADFLLNTVDVELIYGGVKYILKVARQSLTMFVLIMNGGHIEIDAHRLNDGGLLLSYDGNSYTTYMKEEVDSYRITIGNKTCVFEKENDPTVLRSPSAGKLTQYTVEDGGHVEAGDSYAEMEVMKMIMTLNVQESGRVKYIKRPGAVLEAGCVVARLELDDPSKVHPAKPFTGELPVQQTLPIMGEKLNQVFHTVLENLTNVMSGYCLPEPIFSIKLKEWVQKLMMTLRHPSLPLLELQDIMTNVSGRIPAPVEKSVRRVMAQYASNITSVLCQFPSQQIANILDCHAATLQRKADREVFFMNTQSIVQLVQRYRSGTRGYMKAVVLDLLKRYLQVEHHFQQAHYDKCVINLREQLKPDMAQVLHCIFSHAQVAKKNQLVIMLIDELCGPDPSLSEELTAILSELTQLSKTEHCKVALRARQVLIASHLPSYELRHNQVESIFLSAIDRYGHQFCPENLKKLILSETTIFDVLPTFFYHVNKVVCMASLEVYVRRGYIAYELNSLQHRQLPDGTCVVEFQFMLPSSHPNRIAVPVSITNPDLLRHSTELYMDSGFSPLCQRMGAMVAFRRFEEFTRNFDDVISCFANVPRDTPLFSKAQTSVYCEEDCKNLREEPIHILNVAIQCAEHLEDEELVPILRTFVQSKKNILVDYGLRRITFLIAQEKEFPKFFTFRARDEFAEDRIYRHLEPALAFQLELSRMRNFDVTAVPCANHKMHLYLGAAKVKEGGEVTDYRFFIRAIIRHSDLITKEASFEYLQNEGERLLLEAMDELEVAFNNTSVRTDCNHIFLNFVPTVIMDPYKIEEAVRSMVMRYGSRLWKLRVLQAEVKINIRETAAGSAIPIRLFITNESGYYLDISLYKEVTDPRSGNIMFHSFGNKQGAQHGMLINTPYVTKDLLQAKRFQAQSLGTTYVYDFPEMFRQALFKLWASPDKYPKDLLTYTELVLDPQGQLVEMNRLPGGNEVGMVAFKMNLKTREYPEGRDVILISNDITFRIGSFGVGEDLLYLRASELARAEGIPQIYLAANSGARIGLAEEIKHVFKVAWVDPEDPHKGFKYLYLTPQEYTRISALNSVHCKHIEEEGESRYVITDIIGKDDGLGVENLRGSGMIAGECSLAYDEIVTISLVTCRALGIGAYLVRLGQRVIQVENSHIILTGASALNKVLGREVYTSNNQLGGVQIMHNNGVSHITVPDDFEGVYTILEWLSYMPKDNHSPVPIITPTDPIDREIEFSPSRAPYDPRWMLAGRSHPTLKGSWQSGFFDQGSFKEILAPWAQTVVTGRARLGGIPVGVIAVETRTVEVVVPADPANLDSEAKITQQAGQVWFPDSAYKTAQVIKDFNQEKLPLMIFANWRGFSGGMKDMYDQVLKFGAYIVDGLRQYKQPILIYIPPYAELRGGSWVVLDSTINPLCIEMYADKESRGGVLEPEGTVEIKFRKKDQIKAMRRIDPTYKKLVEQLGAADLSDKERKDLEGRLKAREELLLPIYHQVAVQFADLHDTPGRMLEKGVISDILEWRTSRTFLYWRLRRLLLEDQVKQEILQVSSELSHVHIQSMLRRWFVETEGAVKAYLWDNNQMVVQWLEQHWQVGDGLRSTIGENIKYLKRDSVLKTIRGLVQENPEVAVDCMMYMSEHISPAQRAQVAHLLSTMDSPAST

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias33-68Polar residues
Compositional bias103-136Polar residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AAPE02036185
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.
AAPE02036186
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.
AAPE02036187
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.

Genome annotation databases

Similar Proteins

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