G1NFJ1 · G1NFJ1_MELGA

Function

Catalytic activity

Cofactor

Protein has several cofactor binding sites:
Fe3+ (UniProtKB | Rhea| CHEBI:29034 )

Zn2+ (UniProtKB | Rhea| CHEBI:29105 )

GO annotations

AspectTerm
Cellular Componentcalcineurin complex
Cellular Componentcytoplasmic side of plasma membrane
Cellular Componentcytosol
Cellular Componentdendritic spine
Cellular Componentglutamatergic synapse
Cellular Componentmitochondrion
Cellular Componentnucleus
Cellular ComponentSchaffer collateral - CA1 synapse
Cellular ComponentZ disc
Molecular FunctionATPase binding
Molecular Functioncalmodulin binding
Molecular Functioncalmodulin-dependent protein phosphatase activity
Molecular Functioncyclosporin A binding
Molecular Functionmetal ion binding
Molecular Functionmyosin phosphatase activity
Molecular Functionprotein dimerization activity
Biological Processcalcineurin-NFAT signaling cascade
Biological Processcalcium ion transport
Biological Processcardiac muscle hypertrophy in response to stress
Biological Processdendrite morphogenesis
Biological Processdephosphorylation
Biological Processexcitatory postsynaptic potential
Biological ProcessG1/S transition of mitotic cell cycle
Biological Processkeratinocyte differentiation
Biological Processmulticellular organismal response to stress
Biological Processnegative regulation of angiotensin-activated signaling pathway
Biological Processnegative regulation of dendrite morphogenesis
Biological Processnegative regulation of gene expression
Biological Processpositive regulation of activated T cell proliferation
Biological Processpositive regulation of cardiac muscle hypertrophy in response to stress
Biological Processpositive regulation of cell migration
Biological Processpositive regulation of connective tissue replacement
Biological Processpositive regulation of endocytosis
Biological Processpositive regulation of gene expression
Biological Processpositive regulation of glomerulus development
Biological Processpositive regulation of osteoblast differentiation
Biological Processpositive regulation of osteoclast differentiation
Biological Processpositive regulation of saliva secretion
Biological Processpositive regulation of transcription by RNA polymerase II
Biological Processpostsynaptic modulation of chemical synaptic transmission
Biological Processprotein import into nucleus
Biological Processregulation of cell proliferation involved in kidney morphogenesis
Biological Processrenal filtration
Biological Processresponse to calcium ion
Biological Processskeletal muscle fiber development
Biological Processtransition between fast and slow fiber

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Serine/threonine-protein phosphatase
  • EC number

Gene names

    • Name
      PPP3CA

Organism names

  • Taxonomic identifier
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Archelosauria > Archosauria > Dinosauria > Saurischia > Theropoda > Coelurosauria > Aves > Neognathae > Galloanserae > Galliformes > Phasianidae > Meleagridinae > Meleagris

Accessions

  • Primary accession
    G1NFJ1

Proteomes

Expression

Gene expression databases

Family & Domains

Features

Showing features for domain, region, compositional bias.

TypeIDPosition(s)Description
Domain97-102Serine/threonine specific protein phosphatases
Region430-470Disordered
Compositional bias442-470Polar residues

Sequence similarities

Belongs to the PPP phosphatase family. PP-2B subfamily.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    470
  • Mass (Da)
    53,050
  • Last updated
    2021-09-29 v2
  • Checksum
    AFF2C6FBAAAF1FCA
MKEGRLEESVALRIITEGASILRQEKNLLDIDAPVTVCGDIHGQFFDLMKLFEVGGSPANTRYLFLGDYVDRGYFSIECVLYLWALKILYPKTLFLLRGNHECRHLTEYFTFKQECKIKYSERVYDACMDAFDCLPLAALMNQQFLCVHGGLSPEINTLDDIRKLDRFKEPPAYGPMCDILWSDPLEDFGNEKTQEHFTHNTVRGCSYFYSYPAVCEFLQHNNLLSILRAHEAQDAGYRMYRKSQTTGFPSLITIFSAPNYLDVYNNKAAVLKYENNVMNIRQFNCSPHPYWLPNFMDVFTWSLPFVGEKVTEMLVNVLNICSDDELGTEEDGFDGATAAARKEVIRNKIRAIGKMARVFSVLREESESVLTLKGLTPTGMLPSGVLSGGKQTLQSATVEAIEADEAIKGFSPQHKITSFEEAKGLDRINERMPPRRDVPSDANLNSINKAISTETNGTDSNGSNSSNIQ

Computationally mapped potential isoform sequences

There is 1 potential isoform mapped to this entry

View all
EntryEntry nameGene nameLength
G5E7Z6G5E7Z6_MELGAPPP3CA460

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias442-470Polar residues

Keywords

Genome annotation databases

Similar Proteins

Disclaimer

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