G0Y287 · BOSS_BOTBR
- ProteinBotryococcus squalene synthase
- GeneSSL-2
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids465 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score3/5
Function
function
Produces squalene when coexpressed with SSL-1 and bisfarnesyl ether and a very small amount of squalene when incubated alone in the presence of NADPH.
Catalytic activity
- H+ + NADPH + presqualene diphosphate = diphosphate + NADP+ + squalene
Features
Showing features for binding site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Binding site | 48 | NADP+ (UniProtKB | ChEBI) | ||||
Sequence: R | ||||||
Binding site | 73 | NADP+ (UniProtKB | ChEBI) | ||||
Sequence: R | ||||||
Binding site | 76 | Mg2+ (UniProtKB | ChEBI) | ||||
Sequence: D | ||||||
Binding site | 79 | Mg2+ (UniProtKB | ChEBI) | ||||
Sequence: E | ||||||
Binding site | 80 | Mg2+ (UniProtKB | ChEBI) | ||||
Sequence: D | ||||||
Binding site | 215 | NADP+ (UniProtKB | ChEBI) | ||||
Sequence: R | ||||||
Binding site | 315 | NADP+ (UniProtKB | ChEBI) | ||||
Sequence: K | ||||||
Binding site | 317 | NADP+ (UniProtKB | ChEBI) | ||||
Sequence: R |
GO annotations
all annotations | all molecular function | nucleotide binding | molecular_function | nucleic acid binding | dna binding | chromatin binding | dna-binding transcription factor activity | rna binding | cytoskeletal motor activity | catalytic activity | nuclease activity | signaling receptor binding | structural molecule activity | transporter activity | binding | protein binding | translation factor activity, rna binding | lipid binding | kinase activity | transferase activity | hydrolase activity | oxygen binding | enzyme regulator activity | carbohydrate binding | signaling receptor activity | translation regulator activity | transcription regulator activity | other molecular function | all biological process | carbohydrate metabolic process | generation of precursor metabolites and energy | nucleobase-containing compound metabolic process | dna metabolic process | translation | lipid metabolic process | transport | response to stress | cell cycle | cell communication | signal transduction | cell-cell signaling | multicellular organism development | circadian rhythm | biological_process | metabolic process | catabolic process | biosynthetic process | response to light stimulus | response to external stimulus | tropism | response to biotic stimulus | response to abiotic stimulus | response to endogenous stimulus | embryo development | post-embryonic development | fruit ripening | abscission | pollination | flower development | cellular process | programmed cell death | photosynthesis | cellular component organization | cell growth | protein metabolic process | cellular homeostasis | secondary metabolic process | reproductive process | cell differentiation | protein modification process | growth | epigenetic regulation of gene expression | response to chemical | anatomical structure development | regulation of molecular function | other biological process | all cellular component | cellular_component | extracellular region | cell wall | intracellular anatomical structure | nucleus | nuclear envelope | nucleoplasm | nucleolus | cytoplasm | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | cytosol | ribosome | cytoskeleton | plasma membrane | chloroplast | plastid | thylakoid | membrane | external encapsulating structure | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | membrane | |
Molecular Function | farnesyl-diphosphate farnesyltransferase activity | |
Molecular Function | farnesyltranstransferase activity | |
Molecular Function | metal ion binding | |
Molecular Function | oxidoreductase activity | |
Biological Process | lipid biosynthetic process |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameBotryococcus squalene synthase
- EC number
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Viridiplantae > Chlorophyta > core chlorophytes > Trebouxiophyceae > Trebouxiophyceae incertae sedis > Elliptochloris clade > Botryococcus
Accessions
- Primary accessionG0Y287
Subcellular Location
UniProt Annotation
GO Annotation
Membrane ; Multi-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Transmembrane | 395-415 | Helical | ||||
Sequence: AIRLLLLVGVVAYFAYAFNLG | ||||||
Transmembrane | 429-449 | Helical | ||||
Sequence: ILDLSQKGLAVASVALLLLVL |
Keywords
- Cellular component
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Chain | PRO_0000421362 | 1-465 | Botryococcus squalene synthase | |||
Sequence: MVKLVEVLQHPDEIVPILQMLHKTYRAKRSYKDPGLAFCYGMLQRVSRSFSVVIQQLPDELRHPICVFYLILRALDTVEDDMNLPNEVKIPLLRTFHEHLFDRSWKLKCGYGPYVDLMENYPLVTDVFLTLSPGAQEVIRDSTRRMGNGMADFIGKDEVHSVAEYDLYCHYVAGLVGSAVAKIFVDSGLEKENLVAEVDLANNMGQFLQKTNVIRDYLEDINEEPAPRMFWPREIWGKYAQELADFKDPANEKAAVQCLNHMVTDALRHCEIGLNVIPLLQNIGILRSCLIPEVMGLRTLTLCYNNPQVFRGVVKMRRGETAKLFMSIYDKRSFYQTYLRLANELEAKCKGEASGDPMVATTLKHVHGIQKSCKAALSSKELLAKSGSALTDDPAIRLLLLVGVVAYFAYAFNLGDVRGEHGVRALGSILDLSQKGLAVASVALLLLVLLARSRLPLLTSASSKQ |
Structure
Sequence
- Sequence statusComplete
- Length465
- Mass (Da)52,149
- Last updated2011-10-19 v1
- Checksum51991D7B4F11483D
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
HQ585059 EMBL· GenBank· DDBJ | AEL16716.1 EMBL· GenBank· DDBJ | mRNA |