G0XUP7 · G0XUP7_COWPX

  • Protein
    Uracil-DNA glycosylase
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    2/5

Function

function

Plays an essential role in viral replication as a component of the DNA polymerase processivity factor. Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

Features

Showing features for active site.

121820406080100120140160180200
TypeIDPosition(s)Description
Active site68Proton acceptor

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Molecular FunctionDNA binding
Molecular Functionhydrolase activity, hydrolyzing N-glycosyl compounds
Biological ProcessDNA repair

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Uracil-DNA glycosylase

Gene names

    • ORF names
      CPXV121
      , CPXV_GER1980_EP4_114

Organism names

Accessions

  • Primary accession
    G0XUP7

Proteomes

Interaction

Subunit

Homodimer. Interacts with protein OPG148. Component of the Uracil-DNA glycosylase(UDG)-OPG148-polymerase complex; OPG148 and UDG form a heterodimeric processivity factor that associates with OPG71 to form the processive polymerase holoenzyme.

Family & Domains

Sequence similarities

Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    218
  • Mass (Da)
    25,079
  • Last updated
    2011-10-19 v1
  • Checksum
    F35BB4EC52D19BB7
MNSVTVSHAPYTITYHDDWEPVMNQLVEFYNEVASWLLRDETSPIPDKFFIQLKQPLRNKRVCVCGIDPYPKDGTGVPFESPNFTKKSIKEIASSISRLTGVIDYKGYNLNIIDGVIPWNYYLSCKLGETKSHAIYWDKISKLLLQHITKHVSVLYCLGKTDFSNIRAKLESPVTTIVGYHPAARDRQFEKDRSFEIINVLLELDNKAPINWAQGFIY

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
HQ420895
EMBL· GenBank· DDBJ
ADZ29659.1
EMBL· GenBank· DDBJ
Genomic DNA
KC813492
EMBL· GenBank· DDBJ
AGY97351.1
EMBL· GenBank· DDBJ
Genomic DNA
KC813496
EMBL· GenBank· DDBJ
AGY98213.1
EMBL· GenBank· DDBJ
Genomic DNA
KC813497
EMBL· GenBank· DDBJ
AGY98425.1
EMBL· GenBank· DDBJ
Genomic DNA
KC813498
EMBL· GenBank· DDBJ
AGY98641.1
EMBL· GenBank· DDBJ
Genomic DNA
KC813500
EMBL· GenBank· DDBJ
AGY99076.1
EMBL· GenBank· DDBJ
Genomic DNA
KC813504
EMBL· GenBank· DDBJ
AGY99916.1
EMBL· GenBank· DDBJ
Genomic DNA
MK035751
EMBL· GenBank· DDBJ
AZY89960.1
EMBL· GenBank· DDBJ
Genomic DNA
MK035758
EMBL· GenBank· DDBJ
AZY91262.1
EMBL· GenBank· DDBJ
Genomic DNA
LT896729
EMBL· GenBank· DDBJ
SNB50207.1
EMBL· GenBank· DDBJ
Genomic DNA
LT896726
EMBL· GenBank· DDBJ
SNB50329.1
EMBL· GenBank· DDBJ
Genomic DNA
LT896731
EMBL· GenBank· DDBJ
SNB50505.1
EMBL· GenBank· DDBJ
Genomic DNA
LT896733
EMBL· GenBank· DDBJ
SNB51663.1
EMBL· GenBank· DDBJ
Genomic DNA
LT896720
EMBL· GenBank· DDBJ
SNB53369.1
EMBL· GenBank· DDBJ
Genomic DNA
LT896723
EMBL· GenBank· DDBJ
SNB57757.1
EMBL· GenBank· DDBJ
Genomic DNA
LT896727
EMBL· GenBank· DDBJ
SNB68946.1
EMBL· GenBank· DDBJ
Genomic DNA
LT993231
EMBL· GenBank· DDBJ
SPN68777.1
EMBL· GenBank· DDBJ
Genomic DNA
LT993232
EMBL· GenBank· DDBJ
SPN69058.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

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