G0USQ5 · G0USQ5_TRYCI

Function

function

Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).

Catalytic activity

Cofactor

FAD (UniProtKB | Rhea| CHEBI:57692 )

Pathway

Carbohydrate metabolism; tricarboxylic acid cycle; fumarate from succinate (eukaryal route): step 1/1.

Features

Showing features for binding site, active site.

TypeIDPosition(s)Description
Binding site30-35FAD (UniProtKB | ChEBI)
Binding site53-68FAD (UniProtKB | ChEBI)
Binding site236FAD (UniProtKB | ChEBI)
Binding site257substrate
Binding site269substrate
Active site301Proton acceptor
Binding site368substrate
Binding site402FAD (UniProtKB | ChEBI)
Binding site413substrate
Binding site418-419FAD (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentmitochondrial inner membrane
Molecular Functionelectron transfer activity
Molecular Functionflavin adenine dinucleotide binding
Molecular Functionsuccinate dehydrogenase (quinone) activity
Biological Processmitochondrial electron transport, succinate to ubiquinone
Biological Processtricarboxylic acid cycle

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial
  • EC number

Gene names

    • ORF names
      TCIL3000_8_6450

Organism names

  • Taxonomic identifier
  • Strain
    • IL3000
  • Taxonomic lineage
    Eukaryota > Discoba > Euglenozoa > Kinetoplastea > Metakinetoplastina > Trypanosomatida > Trypanosomatidae > Trypanosoma > Nannomonas

Accessions

  • Primary accession
    G0USQ5

Organism-specific databases

Subcellular Location

Membrane
; Peripheral membrane protein
Mitochondrion inner membrane
; Peripheral membrane protein

Keywords

  • Cellular component

PTM/Processing

Features

Showing features for modified residue.

TypeIDPosition(s)Description
Modified residue61Tele-8alpha-FAD histidine

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain25-419FAD-dependent oxidoreductase 2 FAD binding
Domain475-609Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal

Sequence similarities

Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    609
  • Mass (Da)
    66,739
  • Last updated
    2011-10-19 v1
  • Checksum
    516DCC3EDDB095AD
MLRCSLARLVSSLSKAYPVIDHTFDCVVVGAGGSGLRAAMGVAASGYNVACVSKLYPSRSHTIAAQGGINAALGNCEEDDWRWHVYDTVKGSDWLGDQDAIQYMCQEAPCVVSELESMGLPFLRTKDGFIYQRAFGGQSIHYGGKQARRTCAASDRTGHAMLHTLYGQSFQYGVNFFNEYYCLDLIVEDGCCRGVVAMSIDDGTIHRFRSKYTILATGGYGRCWFTTTSAKSCTGDGTAMVARAGLPAEDMEFVQFHPTGIYGPGVLITEGARGEGGYLVNSEGERFMERYAPKAKDLASRDVVSRAITLEVLAGRGCGAKKDHVLLQLHHLPPEQLHQKLPGISESAHIFAGVDVTKESIPIVPTVHYSMGGVPTLWTGEVVSPRNGDDDAIVPGLLAAGECACASVHGANRLGANSLLDIVVFGKSCANTVIFNLTKEGRKQPELRADAGESSIADLDRILNNKGDIPVARIRERMKETMALYAAVFRTEESMLKGRSIIEECYRDYSHIFVHDKSPVWNSNLIEALELRNLLCNALMTITGAAVRRESRGAHARDDYPERDDHNWMKHTLAYMDDVKGKVNLSYRRVHNEMLTSELESIPPAKRVY

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
HE575321
EMBL· GenBank· DDBJ
CCC92418.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

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