G0SH86 · G0SH86_CHATD

Function

function

Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NBP35-CFD1 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins.

Features

Showing features for binding site.

131020406080100120140160180200220240260280300
TypeIDPosition(s)Description
Binding site15-22ATP (UniProtKB | ChEBI)
Binding site199[4Fe-4S] cluster (UniProtKB | ChEBI); ligand shared between dimeric partners
Binding site199[4Fe-4S] cluster (UniProtKB | ChEBI)
Binding site202[4Fe-4S] cluster (UniProtKB | ChEBI); ligand shared between dimeric partners
Binding site202[4Fe-4S] cluster (UniProtKB | ChEBI)

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentcytoplasm
Molecular Function4 iron, 4 sulfur cluster binding
Molecular FunctionATP binding
Molecular FunctionATP-dependent FeS chaperone activity
Molecular Functionmetal ion binding
Biological Processiron-sulfur cluster assembly

Keywords

Names & Taxonomy

Protein names

  • Submitted names
    • Cytosolic Fe-S cluster assembling factor cfd1-like protein

Gene names

    • ORF names
      CTHT_0069100

Organism names

Accessions

  • Primary accession
    G0SH86

Proteomes

Subcellular Location

Keywords

Interaction

Protein-protein interaction databases

Family & Domains

Sequence similarities

Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP2/CFD1 subfamily.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    310
  • Mass (Da)
    33,239
  • Last updated
    2011-10-19 v1
  • Checksum
    0F3BE634AEB4BD6E
MSLSQVKHIILVLSGKGGVGKSSVTTQLALSLSQAGYSVGVLDVDLTGPSIPRMFAVEDAKVKQGSGGWLPVVVHEANPSTGIGSLRVMSLGFLLPRRGDAVIWRGPKKTAMVRQFMSDVLWDELDFLLVDTPPGTSDEHISLAETLLQEARPGQLSGAIVVTTPQAVATADVRKELNFCKKTGIRVLGVVENMSGFVCPNCSECTNIFSSGGGEIMANDFNVRFLGRVPIDPQFLVLIETGKRPRYPEGTKVNSQDLSFQHLEQVDNADNPETPNSSLLVDKYRDCSLAPIFRAITADVVVAVEQASGS

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
GL988047
EMBL· GenBank· DDBJ
EGS17575.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

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