G0M011 · G0M011_LACPE

Function

function

Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i6A).

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.

Catalytic activity

Cofactor

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Features

Showing features for binding site, site.

131120406080100120140160180200220240260280300
Type
IDPosition(s)Description
Binding site14-21ATP (UniProtKB | ChEBI)
Binding site16-21substrate
Site105Interaction with substrate tRNA
Site130Interaction with substrate tRNA

GO annotations

AspectTerm
Molecular FunctionATP binding
Molecular FunctiontRNA dimethylallyltransferase activity
Biological ProcesstRNA modification

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    tRNA dimethylallyltransferase
  • EC number
  • Alternative names
    • Dimethylallyl diphosphate:tRNA dimethylallyltransferase
      (DMAPP:tRNA dimethylallyltransferase
      ; DMATase
      )
    • Isopentenyl-diphosphate:tRNA isopentenyltransferase
      (IPP transferase
      ; IPPT
      ; IPTase
      )

Gene names

    • Name
      miaA
    • ORF names
      LPENT_00400

Organism names

Accessions

  • Primary accession
    G0M011

Interaction

Subunit

Monomer.

Family & Domains

Features

Showing features for region.

TypeIDPosition(s)Description
Region39-42Interaction with substrate tRNA

Sequence similarities

Belongs to the IPP transferase family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    311
  • Mass (Da)
    34,492
  • Last updated
    2011-10-19 v1
  • Checksum
    160BC0F2955D0C99
MATIPKHKVLLIAGPTAVGKTALSLALAKQLNGEIISGDSMQVYRHLDIGTAKIMPDERAGIPHYLIDIKTVDQRFTVAEFVSRATALINDITARGKLPIIVGGTGFYLQSLLAGYQFGPNDNAPDMAYRQQWFDRAANAGNQAVWDALNQRDPQAAAAIAPANLVRVVRALEYLHTTGQLFSAQADTATETLDAYTLCLTAERSLLYDRINQRVDLMLNVGLEAEARWLYDQGGADLPAGKGIGYHEWFPYFAGTQSRDATIAAIKQDSRRYAKRQLTWFRNKMTVDWVDLLEHPELRASIDQRLASWLS

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
FR874854
EMBL· GenBank· DDBJ
CCC15704.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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