F9WE35 · F9WE35_TRYCI

Function

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

  • Preference for hydrophobic residues at P1 and P1' and basic residues at P2' and P3'. A model nonapeptide is cleaved at -Ala-Tyr-|-Leu-Lys-Lys-.
    EC:3.4.24.36 (UniProtKB | ENZYME | Rhea)

Cofactor

Zn2+ (UniProtKB | Rhea| CHEBI:29105 )

Note: Binds 1 zinc ion per subunit.

Features

Showing features for binding site, active site.

155850100150200250300350400450500550
Type
IDPosition(s)Description
Binding site235Zn2+ (UniProtKB | ChEBI); catalytic
Active site236
Binding site239Zn2+ (UniProtKB | ChEBI); catalytic
Binding site304Zn2+ (UniProtKB | ChEBI); catalytic

GO annotations

AspectTerm
Cellular Componentcytoplasm
Cellular Componentmembrane
Molecular Functionmetal ion binding
Molecular Functionmetalloendopeptidase activity
Biological Processcell adhesion
Biological Processproteolysis

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Leishmanolysin-like peptidase
  • EC number

Gene names

    • Name
      MSP-B1
    • ORF names
      TCIL3000_0_06380

Organism names

  • Taxonomic identifier
  • Strain
    • IL3000
  • Taxonomic lineage
    Eukaryota > Discoba > Euglenozoa > Kinetoplastea > Metakinetoplastina > Trypanosomatida > Trypanosomatidae > Trypanosoma > Nannomonas

Accessions

  • Primary accession
    F9WE35

Proteomes

Organism-specific databases

Subcellular Location

PTM/Processing

Features

Showing features for signal, chain.

Type
IDPosition(s)Description
Signal1-39
ChainPRO_500339020740-558Leishmanolysin-like peptidase

Keywords

Family & Domains

Sequence similarities

Belongs to the peptidase M8 family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    558
  • Mass (Da)
    59,679
  • Last updated
    2011-10-19 v1
  • Checksum
    03DA0A95F8B7DC55
MILISPNASTRKTLTHQAMTPMRSSLALLLLTLLHRVLGSSVPPSPRCISDEVTARAGPPVRLATRNIAHSQTGADSEWSNIRIVTFTKDIEDERKHCTAEGQKRPTFFGDTADCTSDDVLTAAKKGLVITRLIPSAVQLHVDRLLVKPEAEPLVLPKFDGKVCSSFTVPASHNTEGVPDADMVMYAAAGPMPAGAAAWATTCIVFDDDRPAAGVMNLGVASISLTETSIRTVAHEIAHSLGFSFYSMSNAKAVTRVPGVRGKKEVVLVSSPRTLQKTREHYKCPAAAGMELEDEGGSGTAMSHWERRNAKDEFMSGISGPGRYTALTMAAFEDLGYYRGAWGMEEPMGWGNSSGCELLTEKCLVEGVTAYPTMFCNGSEVGLTCTSDGFALGKCLTVQYESELPAEYQYFSDTKLGGSAHTLMDYCPYIFGYSNTQCSDGDIRHMYGSVIGPSSKCLKGNKLLDNESRPVGDVCADVRCDNGTVSVRYLGNSEWHLCPAGGAVTPTETFTGGTILCPKYEEVCIVAAVVTKSDTTNPFASVAQPLLLALLVAAVSSS

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CAEQ01001944
EMBL· GenBank· DDBJ
CCD15541.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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