F9NS85 · F9NS85_9ACTN

Function

function

Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

[4Fe-4S] cluster (UniProtKB | Rhea| CHEBI:49883 )

Note: Binds 1 [4Fe-4S] cluster.

Pathway

Isoprenoid biosynthesis; isopentenyl diphosphate biosynthesis via DXP pathway; isopentenyl diphosphate from 1-deoxy-D-xylulose 5-phosphate: step 5/6.

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site335[4Fe-4S] cluster (UniProtKB | ChEBI)
Binding site338[4Fe-4S] cluster (UniProtKB | ChEBI)
Binding site370[4Fe-4S] cluster (UniProtKB | ChEBI)
Binding site377[4Fe-4S] cluster (UniProtKB | ChEBI)

GO annotations

AspectTerm
Molecular Function4 iron, 4 sulfur cluster binding
Molecular Function4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase activity (ferredoxin)
Molecular Function4-hydroxy-3-methylbut-2-enyl-diphosphate synthase activity (flavodoxin)
Molecular Functioniron ion binding
Biological Processisopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway
Biological Processterpenoid biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin)
  • EC number
  • Alternative names
    • 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase

Gene names

    • Name
      ispG
    • ORF names
      HMPREF1162_0887

Organism names

Accessions

  • Primary accession
    F9NS85

Proteomes

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for region, compositional bias.

Type
IDPosition(s)Description
Region18-44Disordered
Compositional bias19-44Basic and acidic residues

Sequence similarities

Belongs to the IspG family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    435
  • Mass (Da)
    46,272
  • Last updated
    2011-10-19 v1
  • Checksum
    543C04779153DA26
MPGVVWRVLAAQLSAVTDGPDDRVDDGSARCQRHHGGDGGDTMETRIRDFRSDTSMTVNLGMPTPPVPTLAPRRKTHQIKVGDVLVGGDAPISVQSMTTTKTHDVGATLQQIAALTAAGCDIVRVACPTDKDAEALPIIAQQSQIPVIADIHFQPKYVFQAIEAGCGAVRVNPGNIRKFDDQIESICKAATEHGTSIRIGVNAGSLDKRLLDKYGAPTAEAMVESALWEASLFEQYGFRDFKISVKHHDPVVMIRAYEQLAAKCDYPLHLGVTEAGPAFQGTIKSAVAFGHLLAEGIGDTIRVSLSADPVEEVKVGIKILESVNLRPRGLEIVSCPSCGRCQVDVLSLANDVTDALEGIDAPLRVAVMGCVVNGLGEGREADLGVAAGNGKGKIFKHGEVIRTVPENEIVQVLVQEANRMSDEMDTTGAVEVTVS

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias19-44Basic and acidic residues

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AFUN01000004
EMBL· GenBank· DDBJ
EGR98171.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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