F8WD41 · F8WD41_HUMAN

  • Protein
    Paraoxonase
  • Gene
    PON3
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Evidence at protein level
  • Annotation score
    2/5

Function

Catalytic activity

Cofactor

Ca2+ (UniProtKB | Rhea| CHEBI:29108 )

Note: Binds 2 calcium ions per subunit.

Features

Showing features for binding site, active site.

127020406080100120140160180200220240260
TypeIDPosition(s)Description
Binding site53Ca2+ 1 (UniProtKB | ChEBI); catalytic
Binding site54Ca2+ 2 (UniProtKB | ChEBI)
Active site114Proton acceptor
Binding site116Ca2+ 1 (UniProtKB | ChEBI); catalytic
Binding site167Ca2+ 1 (UniProtKB | ChEBI); catalytic
Binding site168Ca2+ 1 (UniProtKB | ChEBI); catalytic
Binding site223Ca2+ 1 (UniProtKB | ChEBI); catalytic

GO annotations

AspectTerm
Molecular Functionacyl-L-homoserine-lactone lactonohydrolase activity
Molecular Functionarylesterase activity
Molecular Functionmetal ion binding

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Paraoxonase
  • EC number

Gene names

    • Name
      PON3

Organism names

  • Taxonomic identifier
  • Organism
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Primates > Haplorrhini > Catarrhini > Hominidae > Homo

Accessions

  • Primary accession
    F8WD41

Proteomes

Organism-specific databases

Disease & Variants

Variants

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The viewer provides 112 variants from UniProt as well as other sources including ClinVar and dbSNP.

Go to variant viewer

Genetic variation databases

PTM/Processing

Keywords

Proteomic databases

Expression

Gene expression databases

Structure

Family & Domains

Sequence similarities

Belongs to the paraoxonase family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    270
  • Mass (Da)
    30,739
  • Last updated
    2011-09-21 v1
  • Checksum
    41F0481EB3C84079
MGKLVALVLLGVGLSLVGEMFLAFRERVNASREVEPVEPENCHLIEELESGSEDIDILPSGLAFISSGLKYPGMPNFAPDEPGKIFLMDLNEQNPRAQALEISGGFDKELFNPHGISIFIDKDNTVYLYVVNHPHMKSTVEIFKFEEQQRSLVYLKTIKHELLKSVNDIVVLGPEQFYATRDHYFTNSLLSFFEMILDLRWTYVLFYSPREVKVVAKGFCSANGITVSADQKYVYVADVAAKNIHIMEKHDNWDLTQLKETFWQDAILIL

Computationally mapped potential isoform sequences

There are 4 potential isoforms mapped to this entry

View all
EntryEntry nameGene nameLength
Q15166PON3_HUMANPON3354
F8WBV4F8WBV4_HUMANPON361
C9JZ99C9JZ99_HUMANPON3245
F2Z2L3F2Z2L3_HUMANPON346

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AC004022
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.
AC005021
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.

Genome annotation databases

Similar Proteins

Disclaimer

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