F8WAL6 · F8WAL6_HUMAN

  • Protein
    Abl interactor 2
  • Gene
    ABI2
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Evidence at protein level
  • Annotation score
    2/5

Function

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentcytosol
Cellular Componentfilopodium
Cellular Componentintracellular membrane-bounded organelle
Cellular Componentlamellipodium
Cellular Componentnucleoplasm

Names & Taxonomy

Subcellular Location

Keywords

Disease & Variants

Variants

We now provide the "Disease & Variants" viewer in its own tab.

The viewer provides 551 variants from UniProt as well as other sources including ClinVar and dbSNP.

Go to variant viewer

Organism-specific databases

Genetic variation databases

PTM/Processing

Features

Showing features for modified residue (large scale data).

TypeIDPosition(s)SourceDescription
Modified residue (large scale data)88PRIDEPhosphoserine
Modified residue (large scale data)175PRIDEPhosphothreonine
Modified residue (large scale data)183PRIDEPhosphoserine
Modified residue (large scale data)191PRIDEPhosphothreonine
Modified residue (large scale data)196PRIDEPhosphoserine
Modified residue (large scale data)198PRIDEPhosphotyrosine
Modified residue (large scale data)200PRIDEPhosphothreonine
Modified residue (large scale data)213PRIDEPhosphotyrosine
Modified residue (large scale data)216PRIDEPhosphoserine
Modified residue (large scale data)224PRIDEPhosphoserine
Modified residue (large scale data)227PRIDEPhosphoserine
Modified residue (large scale data)231PRIDEPhosphothreonine
Modified residue (large scale data)233PRIDEPhosphoserine
Modified residue (large scale data)242PRIDEPhosphoserine
Modified residue (large scale data)243PRIDEPhosphoserine
Modified residue (large scale data)244PRIDEPhosphoserine
Modified residue (large scale data)361PRIDEPhosphothreonine
Modified residue (large scale data)364PRIDEPhosphothreonine
Modified residue (large scale data)368PRIDEPhosphoserine
Modified residue (large scale data)371PRIDEPhosphotyrosine
Modified residue (large scale data)489PRIDEPhosphotyrosine

Proteomic databases

Expression

Gene expression databases

Structure

Family & Domains

Features

Showing features for domain, region, compositional bias.

Type
IDPosition(s)Description
Domain45-107T-SNARE coiled-coil homology
Region167-388Disordered
Compositional bias217-265Polar residues
Compositional bias272-290Pro residues
Compositional bias373-388Polar residues
Region426-459Disordered
Compositional bias428-449Pro residues
Domain480-539SH3

Sequence similarities

Belongs to the ABI family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    542
  • Mass (Da)
    58,778
  • Last updated
    2020-12-02 v3
  • Checksum
    22448A592D0D54C7
MAELQMLLEEEIPGGRRALFDSYTNLERVADYCENNYIQSADKQRALEETKAYTTQSLASVAYLINTLANNVLQMLDIQASQLRRMESSINHISQTVDIHKEKVARREIGILTTNKNTSRTHKIIAPANLERPVRYIRKPIDYTILDDIGHGVKWLLRFKVSTQNMKMGGLPRTTPPTQKPPSPPMSGKGTLGRHSPYRTLEPVRPPVVPNDYVPSPTRNMAPSQQSPVRTASVNQRNRTYSSSGSSGGSHPSSRSSSRENSGSGSVGVPIAVPTPSPPSVFPAPAGSAGTPPLPATSASAPAPLVPATVPSSTAPDAAAGGAQTLADGFTSPTPPVVSSTPPTGHPVQFYSMNRPASRHTPPTIGGSLPYRRPPSITSQTSLQNQMNGGPFYSQNPVSLAPPPPSILQVTPQLPLMGFVARVQENISDTPPPPPPVEEPVFDESPPPPPPPEDYEEEEAAVVEYSDPYAEEDPPWAPRSYLEKVVAIYDYTKDKEDELSFQEGAIIYVIKKNDDGWYEGVMNGVTGLFPGNYVESIMHYSE

Computationally mapped potential isoform sequences

There are 16 potential isoforms mapped to this entry

View all
EntryEntry nameGene nameLength
Q9NYB9ABI2_HUMANABI2513
E7EW77E7EW77_HUMANABI2480
E7EUA1E7EUA1_HUMANABI244
E7EP65E7EP65_HUMANABI2486
F8WEB9F8WEB9_HUMANABI2108
F8WAU3F8WAU3_HUMANABI253
F8WAZ8F8WAZ8_HUMANABI275
F8WAQ3F8WAQ3_HUMANABI243
F8WCD7F8WCD7_HUMANABI259
F8WBL5F8WBL5_HUMANABI287
H0Y6B5H0Y6B5_HUMANABI2293
A0A7D9NKC8A0A7D9NKC8_HUMANABI2513
A0A0A0MQU9A0A0A0MQU9_HUMANABI2104
H7C3Q7H7C3Q7_HUMANABI2201
E9PEZ7E9PEZ7_HUMANABI2458
A0A0C4DG21A0A0C4DG21_HUMANABI2507

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias217-265Polar residues
Compositional bias272-290Pro residues
Compositional bias373-388Polar residues
Compositional bias428-449Pro residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AC018891
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.
AC080075
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.

Genome annotation databases

Similar Proteins

Disclaimer

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