F8VPT7 · F8VPT7_MOUSE
- Proteinnon-specific serine/threonine protein kinase
- GeneSik2
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids931 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score3/5
Function
Catalytic activity
- ATP + L-seryl-[protein] = ADP + H+ + O-phospho-L-seryl-[protein]
Cofactor
Features
Showing features for binding site, active site.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | endoplasmic reticulum membrane | |
Molecular Function | ATP binding | |
Molecular Function | magnesium ion binding | |
Molecular Function | protein serine kinase activity | |
Molecular Function | protein serine/threonine kinase activity | |
Biological Process | intracellular signal transduction |
Keywords
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended namenon-specific serine/threonine protein kinase
- EC number
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Glires > Rodentia > Myomorpha > Muroidea > Muridae > Murinae > Mus > Mus
Accessions
- Primary accessionF8VPT7
Proteomes
Organism-specific databases
Subcellular Location
UniProt Annotation
GO Annotation
PTM/Processing
Proteomic databases
Expression
Gene expression databases
Structure
Family & Domains
Features
Showing features for domain, region, compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 20-271 | Protein kinase | ||||
Sequence: YDIEGTLGKGNFAVVKLGRHRITKTEVAIKIIDKSQLDAVNLEKIYREVQIMKMLDHPHIIKLYQVMETKSMLYLVTEYAKNGEIFDYLANHGRLNESEARRKFWQILSAVDYCHGRKVVHRDLKAENLLLDNNMNIKIADFGFGNFFKTGELLATWCGSPPYAAPEVFEGQQYEGPQLDIWSMGVVLYVLVCGALPFDGPTLPILRQRVLEGRFRIPYFMSEDCEHLIRRMLVLDPSKRLSIAQIKEHKWM | ||||||
Domain | 295-335 | UBA | ||||
Sequence: EFNEQVLRLMHSLGIDQQKTVESLQNKSYNHFAAIYFLLVE | ||||||
Region | 565-586 | Disordered | ||||
Sequence: LSSQKREAHNRSPVSFREGRRA | ||||||
Region | 631-662 | Disordered | ||||
Sequence: TLTSTAPQLQDLSSSCPQEEISQQQESVSSLS | ||||||
Region | 744-768 | Disordered | ||||
Sequence: YPGPSQQLALPHQETPLTSQQPPSF | ||||||
Region | 798-842 | Disordered | ||||
Sequence: QLQPLPSTPGPQAPPPLPSQLQQHQQPPPPPPPPPPQQPGAAPTS | ||||||
Compositional bias | 801-838 | Pro residues | ||||
Sequence: PLPSTPGPQAPPPLPSQLQQHQQPPPPPPPPPPQQPGA |
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length931
- Mass (Da)104,182
- Last updated2011-09-21 v1
- ChecksumD182D259DAA28668
Computationally mapped potential isoform sequences
There are 3 potential isoforms mapped to this entry
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 801-838 | Pro residues | ||||
Sequence: PLPSTPGPQAPPPLPSQLQQHQQPPPPPPPPPPQQPGA |
Keywords
- Technical term