F8VPR5 · F8VPR5_MOUSE
- Proteinhistone acetyltransferase
- GeneCrebbp
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids2441 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score4/5
Function
Catalytic activity
- (S)-lactoyl-CoA + L-lysyl-[protein] = CoA + H+ + N6-[(S)-lactoyl]-L-lysyl-[protein]This reaction proceeds in the forward direction.
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended namehistone acetyltransferase
- EC number
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Glires > Rodentia > Myomorpha > Muroidea > Muridae > Murinae > Mus > Mus
Accessions
- Primary accessionF8VPR5
Proteomes
Organism-specific databases
Subcellular Location
PTM/Processing
Expression
Gene expression databases
Interaction
Protein-protein interaction databases
Family & Domains
Features
Showing features for region, compositional bias, domain, zinc finger.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Region | 1-29 | Disordered | ||||
Sequence: MAENLLDGPPNPKRAKLSSPGFSANDNTD | ||||||
Region | 73-168 | Disordered | ||||
Sequence: LRGGSGSSINPGIGNVSASSPVQQGLGGQAQGQPNSTNMASLGAMGKSPLNQGDSSTPNLPKQAASTSGPTPPASQALNPQAQKQVGLVTSSPATS | ||||||
Region | 261-292 | Disordered | ||||
Sequence: GGMTKMGMTGTTSPFGQPFSQTGGQQMGATGV | ||||||
Compositional bias | 262-292 | Polar residues | ||||
Sequence: GMTKMGMTGTTSPFGQPFSQTGGQQMGATGV | ||||||
Domain | 346-432 | TAZ-type | ||||
Sequence: DPEKRKLIQQQLVLLLHAHKCQRREQANGEVRACSLPHCRTMKNVLNHMTHCQAGKACQVAHCASSRQIISHWKNCTRHDCPVCLPL | ||||||
Zinc finger | 346-432 | TAZ-type | ||||
Sequence: DPEKRKLIQQQLVLLLHAHKCQRREQANGEVRACSLPHCRTMKNVLNHMTHCQAGKACQVAHCASSRQIISHWKNCTRHDCPVCLPL | ||||||
Domain | 586-665 | KIX | ||||
Sequence: GVRKGWHEHVTQDLRSHLVHKLVQAIFPTPDPAALKDRRMENLVAYAKKVEGDMYESANSRDEYYHLLAEKIYKIQKELE | ||||||
Compositional bias | 792-821 | Polar residues | ||||
Sequence: FLPQNQFPSSSGAMSVNSVGMGQPAAQAGV | ||||||
Region | 792-1088 | Disordered | ||||
Sequence: FLPQNQFPSSSGAMSVNSVGMGQPAAQAGVSQGQVPGAALPNPLNMLAPQASQLPCPPVTQSPLHPTPPPASTAAGMPSLQHPTAPGMTPPQPAAPTQPSTPVSSGQTPTPTPGSVPSAAQTQSTPTVQAAAQAQVTPQPQTPVQPPSVATPQSSQQQPTPVHTQPPGTPLSQAAASIDNRVPTPSSVTSAETSSQQPGPDVPMLEMKTEVQTDDAEPEPTESKGEPRSEMMEEDLQGSSQVKEETDTTEQKSEPMEVEEKKPEVKVEAKEEEENSSNDTASQSTSPSQPRKKIFKP | ||||||
Compositional bias | 850-864 | Pro residues | ||||
Sequence: VTQSPLHPTPPPAST | ||||||
Compositional bias | 875-889 | Pro residues | ||||
Sequence: TAPGMTPPQPAAPTQ | ||||||
Compositional bias | 890-930 | Polar residues | ||||
Sequence: PSTPVSSGQTPTPTPGSVPSAAQTQSTPTVQAAAQAQVTPQ | ||||||
Compositional bias | 939-991 | Polar residues | ||||
Sequence: SVATPQSSQQQPTPVHTQPPGTPLSQAAASIDNRVPTPSSVTSAETSSQQPGP | ||||||
Compositional bias | 999-1068 | Basic and acidic residues | ||||
Sequence: KTEVQTDDAEPEPTESKGEPRSEMMEEDLQGSSQVKEETDTTEQKSEPMEVEEKKPEVKVEAKEEEENSS | ||||||
Domain | 1104-1176 | Bromo | ||||
Sequence: RQDPESLPFRQPVDPQLLGIPDYFDIVKNPMDLSTIKRKLDTGQYQEPWQYVDDVWLMFNNAWLYNRKTSRVY | ||||||
Domain | 1324-1701 | CBP/p300-type HAT | ||||
Sequence: KFSAKRLQTTRLGNHLEDRVNKFLRRQNHPEAGEVFVRVVASSDKTVEVKPGMKSRFVDSGEMSESFPYRTKALFAFEEIDGVDVCFFGMHVQEYGSDCPPPNTRRVYISYLDSIHFFRPRCLRTAVYHEILIGYLEYVKKLGYVTGHIWACPPSEGDDYIFHCHPPDQKIPKPKRLQEWYKKMLDKAFAERIINDYKDIFKQANEDRLTSAKELPYFEGDFWPNVLEESIKELEQEEEERKKEESTAASETPEGSQGDSKNAKKKNNKKTNKNKSSISRANKKKPSMPNVSNDLSQKLYATMEKHKEVFFVIHLHAGPVISTQPPIVDPDPLLSCDLMDGRDAFLTLARDKHWEFSSLRRSKWSTLCMLVELHTQGQ | ||||||
Compositional bias | 1557-1572 | Basic and acidic residues | ||||
Sequence: LEQEEEERKKEESTAA | ||||||
Region | 1557-1616 | Disordered | ||||
Sequence: LEQEEEERKKEESTAASETPEGSQGDSKNAKKKNNKKTNKNKSSISRANKKKPSMPNVSN | ||||||
Compositional bias | 1589-1603 | Basic residues | ||||
Sequence: KNNKKTNKNKSSISR | ||||||
Domain | 1703-1751 | ZZ-type | ||||
Sequence: RFVYTCNECKHHVETRWHCTVCEDYDLCINCYNTKSHTHKMVKWGLGLD | ||||||
Domain | 1766-1847 | TAZ-type | ||||
Sequence: QESRRLSIQRCIQSLVHACQCRNANCSLPSCQKMKRVVQHTKGCKRKTNGGCPVCKQLIALCCYHAKHCQENKCPVPFCLNI | ||||||
Zinc finger | 1766-1847 | TAZ-type | ||||
Sequence: QESRRLSIQRCIQSLVHACQCRNANCSLPSCQKMKRVVQHTKGCKRKTNGGCPVCKQLIALCCYHAKHCQENKCPVPFCLNI | ||||||
Region | 1875-1959 | Disordered | ||||
Sequence: TRNVPQQSLPSPTSAPPGTPTQQPSTPQTPQPPAQPQPSPVNMSPAGFPNVARTQPPTIVSAGKPTNQVPAPPPPAQPPPAAVEA | ||||||
Compositional bias | 1884-1917 | Pro residues | ||||
Sequence: PSPTSAPPGTPTQQPSTPQTPQPPAQPQPSPVNM | ||||||
Compositional bias | 1922-1939 | Polar residues | ||||
Sequence: FPNVARTQPPTIVSAGKP | ||||||
Compositional bias | 1941-1955 | Pro residues | ||||
Sequence: NQVPAPPPPAQPPPA | ||||||
Compositional bias | 2112-2146 | Polar residues | ||||
Sequence: NQPGMQPQPGLQSQPGMQPQPGMHQQPSLQNLNAM | ||||||
Region | 2112-2421 | Disordered | ||||
Sequence: NQPGMQPQPGLQSQPGMQPQPGMHQQPSLQNLNAMQAGVPRPGVPPPQPAMGGLNPQGQALNIMNPGHNPNMTNMNPQYREMVRRQLLQHQQQQQQQQQQQQQQQNSASLAGGMAGHSQFQQPQGPGGYAPAMQQQRMQQHLPIQGSSMGQMAAPMGQLGQMGQPGLGADSTPNIQQALQQRILQQQQMKQQIGSPGQPNPMSPQQHMLSGQPQASHLPGQQIATSLSNQVRSPAPVQSPRPQSQPPHSSPSPRIQPQPSPHHVSPQTGSPHPGLAVTMASSMDQGHLGNPEQSAMLPQLNTPNRSALSS | ||||||
Compositional bias | 2169-2265 | Polar residues | ||||
Sequence: GQALNIMNPGHNPNMTNMNPQYREMVRRQLLQHQQQQQQQQQQQQQQQNSASLAGGMAGHSQFQQPQGPGGYAPAMQQQRMQQHLPIQGSSMGQMAA | ||||||
Compositional bias | 2276-2349 | Polar residues | ||||
Sequence: PGLGADSTPNIQQALQQRILQQQQMKQQIGSPGQPNPMSPQQHMLSGQPQASHLPGQQIATSLSNQVRSPAPVQ | ||||||
Compositional bias | 2350-2377 | Pro residues | ||||
Sequence: SPRPQSQPPHSSPSPRIQPQPSPHHVSP | ||||||
Compositional bias | 2394-2421 | Polar residues | ||||
Sequence: MDQGHLGNPEQSAMLPQLNTPNRSALSS |
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length2,441
- Mass (Da)265,567
- Last updated2011-09-21 v1
- Checksum79A370F30FFB2A7C
Computationally mapped potential isoform sequences
There are 6 potential isoforms mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
P45481 | CBP_MOUSE | Crebbp | 2441 | ||
A0A0U1RPL2 | A0A0U1RPL2_MOUSE | Crebbp | 1107 | ||
A0A0U1RPQ3 | A0A0U1RPQ3_MOUSE | Crebbp | 247 | ||
A0A0U1RQB6 | A0A0U1RQB6_MOUSE | Crebbp | 2403 | ||
A0A0U1RP46 | A0A0U1RP46_MOUSE | Crebbp | 127 | ||
A0A0U1RP23 | A0A0U1RP23_MOUSE | Crebbp | 172 |
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 262-292 | Polar residues | ||||
Sequence: GMTKMGMTGTTSPFGQPFSQTGGQQMGATGV | ||||||
Compositional bias | 792-821 | Polar residues | ||||
Sequence: FLPQNQFPSSSGAMSVNSVGMGQPAAQAGV | ||||||
Compositional bias | 850-864 | Pro residues | ||||
Sequence: VTQSPLHPTPPPAST | ||||||
Compositional bias | 875-889 | Pro residues | ||||
Sequence: TAPGMTPPQPAAPTQ | ||||||
Compositional bias | 890-930 | Polar residues | ||||
Sequence: PSTPVSSGQTPTPTPGSVPSAAQTQSTPTVQAAAQAQVTPQ | ||||||
Compositional bias | 939-991 | Polar residues | ||||
Sequence: SVATPQSSQQQPTPVHTQPPGTPLSQAAASIDNRVPTPSSVTSAETSSQQPGP | ||||||
Compositional bias | 999-1068 | Basic and acidic residues | ||||
Sequence: KTEVQTDDAEPEPTESKGEPRSEMMEEDLQGSSQVKEETDTTEQKSEPMEVEEKKPEVKVEAKEEEENSS | ||||||
Compositional bias | 1557-1572 | Basic and acidic residues | ||||
Sequence: LEQEEEERKKEESTAA | ||||||
Compositional bias | 1589-1603 | Basic residues | ||||
Sequence: KNNKKTNKNKSSISR | ||||||
Compositional bias | 1884-1917 | Pro residues | ||||
Sequence: PSPTSAPPGTPTQQPSTPQTPQPPAQPQPSPVNM | ||||||
Compositional bias | 1922-1939 | Polar residues | ||||
Sequence: FPNVARTQPPTIVSAGKP | ||||||
Compositional bias | 1941-1955 | Pro residues | ||||
Sequence: NQVPAPPPPAQPPPA | ||||||
Compositional bias | 2112-2146 | Polar residues | ||||
Sequence: NQPGMQPQPGLQSQPGMQPQPGMHQQPSLQNLNAM | ||||||
Compositional bias | 2169-2265 | Polar residues | ||||
Sequence: GQALNIMNPGHNPNMTNMNPQYREMVRRQLLQHQQQQQQQQQQQQQQQNSASLAGGMAGHSQFQQPQGPGGYAPAMQQQRMQQHLPIQGSSMGQMAA | ||||||
Compositional bias | 2276-2349 | Polar residues | ||||
Sequence: PGLGADSTPNIQQALQQRILQQQQMKQQIGSPGQPNPMSPQQHMLSGQPQASHLPGQQIATSLSNQVRSPAPVQ | ||||||
Compositional bias | 2350-2377 | Pro residues | ||||
Sequence: SPRPQSQPPHSSPSPRIQPQPSPHHVSP | ||||||
Compositional bias | 2394-2421 | Polar residues | ||||
Sequence: MDQGHLGNPEQSAMLPQLNTPNRSALSS |
Keywords
- Technical term