F7ZBA2 · F7ZBA2_ROSLO

Function

function

Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.

Catalytic activity

Cofactor

Protein has several cofactor binding sites:
Co2+ (UniProtKB | Rhea| CHEBI:48828 )

Zn2+ (UniProtKB | Rhea| CHEBI:29105 )

Note: Binds 1 divalent metal cation per subunit. Can use either Co2+ or Zn2+.
NAD+ (UniProtKB | Rhea| CHEBI:57540 )

Pathway

Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 2/7.

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site107-111NAD+ (UniProtKB | ChEBI)
Binding site131-132NAD+ (UniProtKB | ChEBI)
Binding site144NAD+ (UniProtKB | ChEBI)
Binding site153NAD+ (UniProtKB | ChEBI)
Binding site186Zn2+ (UniProtKB | ChEBI)
Binding site249Zn2+ (UniProtKB | ChEBI)
Binding site267Zn2+ (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular Function3-dehydroquinate synthase activity
Molecular Functionmetal ion binding
Molecular Functionnucleotide binding
Biological Processamino acid biosynthetic process
Biological Processaromatic amino acid family biosynthetic process
Biological Processchorismate biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    3-dehydroquinate synthase
  • EC number
  • Short names
    DHQS

Gene names

    • Name
      aroB
    • Ordered locus names
      RLO149_c023180

Organism names

Accessions

  • Primary accession
    F7ZBA2

Proteomes

Subcellular Location

Keywords

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain69-3323-dehydroquinate synthase

Sequence similarities

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    370
  • Mass (Da)
    39,169
  • Last updated
    2011-09-21 v1
  • Checksum
    9FADCDA5E3A34FFF
MIETVHVDLPGRAYDVRIGPGLVSEAGAHILPLLNRPKVAVVTDETVAALHLDALRAGLAREGIEMTALALPAGEATKSWEPLERTVGWLLDQKVERGDVVVAFGGGVIGDLAGFAAAILRRGVRFVQIPTSLLAQVDSSVGGKTGINAAQGKNLIGAFHQPSLVLADIDVLGSLTARDFLAGYGEVVKYGLLGDLAFFEWLEENGPTLAVGNQQARCEAVRRSVQMKADIVIRDETEQGDRALLNLGHTFGHALEAATGYSDRLLHGEGVAIGCAMAFELSSRMGLCSQESPSRVRAHLKAMGMKTDLRDIPGELPDAAGLLDLMGQDKKVMQGTLHFILARGLGEAFVTSDVAAGDVLTVLEDALRGR

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP002623
EMBL· GenBank· DDBJ
AEI94288.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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