F7VPK9 · F7VPK9_SORMK
- ProteinGlutathione hydrolase
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids613 (go to sequence)
- Protein existencePredicted
- Annotation score3/5
Function
function
Cleaves the gamma-glutamyl peptide bond of glutathione and glutathione conjugates.
Catalytic activity
- an S-substituted glutathione + H2O = an S-substituted L-cysteinylglycine + L-glutamate
Pathway
Sulfur metabolism; glutathione metabolism.
Features
Showing features for binding site, active site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Binding site | 125 | L-glutamate (UniProtKB | ChEBI) | ||||
Sequence: R | ||||||
Active site | 401 | Nucleophile | ||||
Sequence: T | ||||||
Binding site | 419-421 | L-glutamate (UniProtKB | ChEBI) | ||||
Sequence: TLN | ||||||
Binding site | 443 | L-glutamate (UniProtKB | ChEBI) | ||||
Sequence: D | ||||||
Binding site | 471-472 | L-glutamate (UniProtKB | ChEBI) | ||||
Sequence: SS | ||||||
Binding site | 495 | L-glutamate (UniProtKB | ChEBI) | ||||
Sequence: G |
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | glutathione hydrolase activity | |
Molecular Function | leukotriene C4 gamma-glutamyl transferase activity | |
Biological Process | glutathione catabolic process |
Keywords
- Molecular function
Enzyme and pathway databases
Protein family/group databases
Names & Taxonomy
Protein names
- Recommended nameGlutathione hydrolase
- EC number
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Fungi > Dikarya > Ascomycota > Pezizomycotina > Sordariomycetes > Sordariomycetidae > Sordariales > Sordariaceae > Sordaria
Accessions
- Primary accessionF7VPK9
Proteomes
Organism-specific databases
Interaction
Protein-protein interaction databases
Structure
Sequence
- Sequence statusComplete
- Length613
- Mass (Da)65,541
- Last updated2011-09-21 v1
- Checksum73717B5A6A8B5C7D
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
CABT02000003 EMBL· GenBank· DDBJ | CCC07437.1 EMBL· GenBank· DDBJ | Genomic DNA |