F7VPK9 · F7VPK9_SORMK

Function

function

Cleaves the gamma-glutamyl peptide bond of glutathione and glutathione conjugates.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Pathway

Sulfur metabolism; glutathione metabolism.

Features

Showing features for binding site, active site.

TypeIDPosition(s)Description
Binding site125L-glutamate (UniProtKB | ChEBI)
Active site401Nucleophile
Binding site419-421L-glutamate (UniProtKB | ChEBI)
Binding site443L-glutamate (UniProtKB | ChEBI)
Binding site471-472L-glutamate (UniProtKB | ChEBI)
Binding site495L-glutamate (UniProtKB | ChEBI)

GO annotations

AspectTerm
Molecular Functionglutathione hydrolase activity
Molecular Functionleukotriene C4 gamma-glutamyl transferase activity
Biological Processglutathione catabolic process

Keywords

Enzyme and pathway databases

Protein family/group databases

Names & Taxonomy

Protein names

  • Recommended name
    Glutathione hydrolase
  • EC number
  • Alternative names
    • Gamma-glutamyltransferase
    • Gamma-glutamyltranspeptidase

Gene names

    • ORF names
      SMAC_02443

Organism names

Accessions

  • Primary accession
    F7VPK9

Proteomes

Organism-specific databases

Interaction

Protein-protein interaction databases

Family & Domains

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    613
  • Mass (Da)
    65,541
  • Last updated
    2011-09-21 v1
  • Checksum
    73717B5A6A8B5C7D
MAIVTTVGRYSGHVRLDAHLSPLLCGLAVLSQLGSVVTAVPLEFKYQRVIQNTSSEGHRGAVASESAICSEIGIDTLRKGGSAADAMVATTLCVGTIGMYHSGIGGGGFMLVRDPDGNYETVDYRETAPAAATKDMYNDDPNASVIGARSVAIPSELRGLEYVHSKYGRLPWHDLVLPSVKIARDGFKVTEDLVRYMTSASVLDDFLTHDPVWAEDFAPNGTLLGLGDTITRKRYAKTLAKIALFGADAFYTGPIADSIIALLQPLGGILTHADLANYEVSIKSALNITYRDSFRIFATDAPSSGAVTLSILKTMEQFPSSSLTSDVPLTNHRFVEAMKFAYGARQSLGDPTFITNVTSFQSSMLSPSTAKLIASKILPNSTLPLSEYDPAKNYAAESHGTSHIVTADRSGLTVSSTTTLNLLFGARLMTPDTGIILNDEMDDFSQPNKNNSFGFVPSPNNFIRAGKRPLSSICPLMVEHVGNGSLWFATGAAGGSRIISSTTQVAFNVLEGLGVHPNTTTEVVKANGVGGEGSVMRAAVAAPRLHDQLMPEVLLVEQGYGQDVYEDLRGRGHNVTWQAPGLSAVQAVMRFGNGTFVRRVRLGRLIVVGLLFR

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CABT02000003
EMBL· GenBank· DDBJ
CCC07437.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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