F7RQE3 · F7RQE3_9GAMM

  • Protein
    Fatty acid oxidation complex subunit alpha
  • Gene
    fadJ
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    4/5

Function

function

Catalyzes the formation of a hydroxyacyl-CoA by addition of water on enoyl-CoA. Also exhibits 3-hydroxyacyl-CoA epimerase and 3-hydroxyacyl-CoA dehydrogenase activities.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Pathway

Lipid metabolism; fatty acid beta-oxidation.

Features

Showing features for site.

TypeIDPosition(s)Description
Site116Important for catalytic activity
Site138Important for catalytic activity

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular Function3-hydroxyacyl-CoA dehydrogenase activity
Molecular Function3-hydroxybutyryl-CoA epimerase activity
Molecular Functionenoyl-CoA hydratase activity
Molecular FunctionNAD+ binding
Biological Processfatty acid beta-oxidation

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Fatty acid oxidation complex subunit alpha

Including 2 domains:

  • Recommended name
    Enoyl-CoA hydratase/3-hydroxybutyryl-CoA epimerase
  • EC number
  • Recommended name
    3-hydroxyacyl-CoA dehydrogenase
  • EC number

Gene names

    • Name
      fadJ
    • ORF names
      SOHN41_02592

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • HN-41
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Gammaproteobacteria > Alteromonadales > Shewanellaceae > Shewanella

Accessions

  • Primary accession
    F7RQE3

Proteomes

Subcellular Location

Keywords

Interaction

Subunit

Heterotetramer of two alpha chains (FadJ) and two beta chains (FadI).

Protein-protein interaction databases

Family & Domains

Features

Showing features for region, domain.

TypeIDPosition(s)Description
Region1-188Enoyl-CoA hydratase
Region308-7083-hydroxyacyl-CoA dehydrogenase
Domain313-4913-hydroxyacyl-CoA dehydrogenase NAD binding
Domain494-5873-hydroxyacyl-CoA dehydrogenase C-terminal
Domain620-7053-hydroxyacyl-CoA dehydrogenase C-terminal

Sequence similarities

In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.
In the central section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    708
  • Mass (Da)
    76,271
  • Last updated
    2011-09-21 v1
  • Checksum
    2E5A2019A2EADCE2
MEKTFNLTRRDDGIAILTMDVPGETMNTLKAQFGPEISEILAEIKRDSSIRGLVLISGKKDSFVAGADISMLDACKTASDAKALSQQGHVVFNELEALTIPVVAAIHGACLGGGLELALACHQRVCSDDGKTMLGVPEVQLGLLPGGGGTQRLPRLVGITTALDMMLTGKQIRPKQALKMGLVNDVVPQTILLQTAVEMALAGKRASKPIKKSLVNQVLEGTSFGRNIIFDQATKQVEKKTQGNYPAPAKIIDCVRQGIAKGMQKGLEVEASHFAELVISKESEALRSIFFATTEMKKETGAEGATPRKVKKAVILGGGLMGGGIASVTTTKAKIPARVKDINEKGLSNALAYAYKLLDKGVKRRHMTPAARDNLMALMTTTTEYKGVKDADIVVEAVFEDLALKHQMVKDIERECGEHTIFASNTSSLPISQIAEAATRPENVIGLHYFSPVEKMPLVEVIAHAKTSPETIATTVAFARKQGKTPIVVQDGAGFYVNRILALYMNEAAQLLLEGQSVEHLDKALVKFGFPVGPITLLDEVGIDVGAKISPILEKELGERFKAPAAFDKLLGDDRKGRKNGKGFYQYGQKDSSKKAKVVDESVYGVLGIKPGTNKDAKAVAERCVVQMLNEAVRCLDEGIIASPRDGDIGAIFGIGFPPFLGGPFHYIDTLGAANLVRILEGYQSQLGDRFEPCERLKAMAQENRRFF

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AFOZ01000031
EMBL· GenBank· DDBJ
EGM69502.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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