F7GWJ0 · F7GWJ0_MACMU

Function

Catalytic activity

Cofactor

Ca2+ (UniProtKB | Rhea| CHEBI:29108 )

Note: Binds 1 Ca2+ ion per subunit.

Features

Showing features for binding site, active site.

1852100200300400500600700800
TypeIDPosition(s)Description
Binding site52Ca2+ (UniProtKB | ChEBI)
Binding site53Ca2+ (UniProtKB | ChEBI)
Active site88Nucleophile
Binding site88Ca2+ (UniProtKB | ChEBI); via 3-oxoalanine
Binding site317Ca2+ (UniProtKB | ChEBI)
Binding site318Ca2+ (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcell surface
Cellular Componentendoplasmic reticulum
Cellular ComponentGolgi stack
Molecular Functioncalcium ion binding
Molecular Functionsulfuric ester hydrolase activity

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Arylsulfatase
  • EC number
  • Alternative names
    • N-acetylglucosamine-6-sulfatase

Gene names

    • Name
      SULF2

Organism names

  • Taxonomic identifier
  • Strain
    • 17573
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Primates > Haplorrhini > Catarrhini > Cercopithecidae > Cercopithecinae > Macaca

Accessions

  • Primary accession
    F7GWJ0

Proteomes

Organism-specific databases

Subcellular Location

Keywords

PTM/Processing

Features

Showing features for signal, chain, modified residue.

TypeIDPosition(s)Description
Signal1-24
ChainPRO_502385452425-852Arylsulfatase
Modified residue883-oxoalanine (Cys)

Post-translational modification

The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

Expression

Gene expression databases

Structure

Family & Domains

Features

Showing features for domain, region, compositional bias, coiled coil.

TypeIDPosition(s)Description
Domain44-374Sulfatase N-terminal
Domain528-664Extracellular sulfatase C-terminal
Region560-588Disordered
Compositional bias566-580Basic and acidic residues
Coiled coil628-655

Sequence similarities

Belongs to the sulfatase family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    852
  • Mass (Da)
    98,063
  • Last updated
    2019-12-11 v3
  • Checksum
    ECBE880FF1D5D3AB
MGPPSLVLCLLSATVFSLLGGSSAFLSHHRLKGRFQRDRRNIRPNIILVLTDDQDVELGSMQVMNKTRRIMEQGGAHFINAFVTTPMCCPSRSSILTGKYVHNHNTYTNNENCSSPSWQAQHESRTFAVYLNSTGYRTAFFGKYLNEYNGSYVPPGWKEWVGLLKNSRFYNYTLCRNGVKEKHGSDYSKDYLTDLITNDSVSFFRTSKKMYPHRPVLMVISHAAPHGPEDSAPQYSRLFPNASQHITPSYNYAPNPDKHWIMRYTGPMKPIHMEFTNILQRKRLQTLMSVDDSMETIYNMLVETGELDNTYIVYTADHGYHIGQFGLVKGKSMPYEFDIRVPFYVRGPNVEAGSLNPHIVLNIDLAPTILDIAGLDIPADMDGKSILKLLDTERPVNRFHLKKKMRVWRDSFLVERGKLLHKRDNDKVDAQEENFLPKYQRVKDLCQRAEYQTACEQLGQKWQCVEDATGKLKLHKCKGPVQLGSSRALSNLVPKYYGQGSEACTCDSGDYKLSLAGRRKKLFKKKYKASYARSRSIRSVAIEVDGRVYHVGLGDAAQPRNLTKRHWPGAPEDQDDKDGGDFSGTGGLPDYSAANPIKVTHRCYILENDTVQCDLDLYKSLQAWKDHKLHIDHEIETLQNKIKNLREVRGHLKKKRPEECDCHKISYHTQHKGRLKHKGSSLHPFRKGLQEKDKVWLLREQKRKKKLRKLLKRLQNNDTCSMPGLTCFTHDNQHWQTAPFWTLGPFCACTSANNNTYWCMRTINETHNFLFCEFATGFLEYFDLNTDPYQLMNAVNTLDRDVLNQLHVQLMELRSCKGYKQCNPRTRNMDLGLKDGGSYEQYRGQLWEGWEG

Computationally mapped potential isoform sequences

There are 4 potential isoforms mapped to this entry

View all
EntryEntry nameGene nameLength
G7N4L2G7N4L2_MACMUSULF2870
F7GWI7F7GWI7_MACMUSULF2850
A0A5F8A4A6A0A5F8A4A6_MACMUSULF2948
A0A5F8ASH3A0A5F8ASH3_MACMUSULF2827

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias566-580Basic and acidic residues

Keywords

Genome annotation databases

Similar Proteins

Disclaimer

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