Homophilic adhesion and CEACAM1-S regulate dimerization of CEACAM1-L and recruitment of SHP-2 and c-Src.
- AnnotationTransmembrane signaling by CEACAM1 operates by alteration of the monomer/dimer equilibrium which leads to changes in the SHP-2 phosphatase/c-Src kinase-binding ratio.
- CategoriesInteraction, Subcellular Location
- SourceGeneRif: 81613