F7DYB8 · F7DYB8_HORSE

  • Protein
    Platelet-derived growth factor C
  • Gene
    PDGFC
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    4/5

Function

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentcell surface
Cellular Componentcytosol
Cellular Componentextracellular space
Cellular Componentplasma membrane
Molecular Functiongrowth factor activity
Molecular Functionplatelet-derived growth factor receptor binding
Molecular Functionprotein homodimerization activity
Biological Processanimal organ morphogenesis
Biological Processbone development
Biological Processcellular response to amino acid stimulus
Biological Processdigestive tract development
Biological Processfibroblast proliferation
Biological Processplatelet-derived growth factor receptor signaling pathway
Biological Processpositive regulation of cell division
Biological Processpositive regulation of cell migration
Biological Processpositive regulation of cell population proliferation
Biological Processpositive regulation of cold-induced thermogenesis
Biological Processpositive regulation of ERK1 and ERK2 cascade
Biological Processpositive regulation of fibroblast proliferation
Biological Processpositive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
Biological Processpositive regulation of protein autophosphorylation
Biological Processregulation of peptidyl-tyrosine phosphorylation

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Platelet-derived growth factor C

Gene names

    • Name
      PDGFC

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • Thoroughbred
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Laurasiatheria > Perissodactyla > Equidae > Equus

Accessions

  • Primary accession
    F7DYB8

Proteomes

Organism-specific databases

Subcellular Location

PTM/Processing

Features

Showing features for signal, chain.

TypeIDPosition(s)Description
Signal1-22
ChainPRO_504030026523-389Platelet-derived growth factor C

Keywords

Proteomic databases

Expression

Gene expression databases

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for compositional bias, region, domain.

TypeIDPosition(s)Description
Compositional bias25-41Polar residues
Region25-44Disordered
Domain90-207CUB
Domain294-386Platelet-derived growth factor (PDGF) family profile

Sequence similarities

Belongs to the PDGF/VEGF growth factor family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    389
  • Mass (Da)
    44,408
  • Last updated
    2023-09-13 v3
  • Checksum
    E6AED44EC0DD412F
MLLFGLLLLTSALAGQRHGTQAESNLSSKFQFSSNKEQNDSEPPRLGFEVTKRLNFTISIYWQGGTIPKHLDWHRKEEKEHLKGVQDPQHERIITVSTNGSIHSPRFPHTYPRNMDLVWRLVAVEENVWIQLTFDERFGLEDPEDDICKYDFVEVEEPSDGTILGRWCGSGTVPGKQISKGNQIRIRFVSDEYFPSEPGFCIHYNIVMPQFTEAVSPSALPPSALPLDLLNNAVTAFSTLEDLIRYLEPDRWQLDLEDLYRPTWQLLGKAFVFGRKSRVVDLNLLKEEVRLYSCTPRNFSVSIREELKRTDTIFWPGCLLVKRCGGNCACCLHNCNECQCVPSKVTKKYHEVLQLRPKNGVRGLHKSLTDVALEHHEECDCVCRGNSGG

Computationally mapped potential isoform sequences

There are 9 potential isoforms mapped to this entry

View all
EntryEntry nameGene nameLength
A0A9L0RNJ1A0A9L0RNJ1_HORSEPDGFC345
A0A9L0RXV5A0A9L0RXV5_HORSEPDGFC210
A0A9L0RTE4A0A9L0RTE4_HORSEPDGFC184
A0A9L0TLR8A0A9L0TLR8_HORSEPDGFC359
A0A9L0R624A0A9L0R624_HORSEPDGFC331
A0A9L0R3W4A0A9L0R3W4_HORSEPDGFC368
A0A9L0R274A0A9L0R274_HORSEPDGFC197
A0A3Q2HV05A0A3Q2HV05_HORSEPDGFC317
A0A9L0SP73A0A9L0SP73_HORSEPDGFC348

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias25-41Polar residues

Keywords

Genome annotation databases

Similar Proteins

Disclaimer

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