F7DM14 · F7DM14_MACMU
- Proteinreceptor protein-tyrosine kinase
- GeneEPHB1
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids978 (go to sequence)
- Protein existencePredicted
- Annotation score3/5
Function
Catalytic activity
- L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H+
Features
Showing features for binding site, active site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 619-627 | ATP (UniProtKB | ChEBI) | |||
Binding site | 645 | ATP (UniProtKB | ChEBI) | |||
Active site | 738 | Proton acceptor | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | dendrite | |
Cellular Component | plasma membrane | |
Molecular Function | ATP binding | |
Molecular Function | ephrin receptor activity | |
Biological Process | nervous system development | |
Biological Process | protein phosphorylation |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended namereceptor protein-tyrosine kinase
- EC number
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Primates > Haplorrhini > Catarrhini > Cercopithecidae > Cercopithecinae > Macaca
Accessions
- Primary accessionF7DM14
Proteomes
Organism-specific databases
Subcellular Location
UniProt Annotation
GO Annotation
Cell membrane ; Single-pass type I membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Transmembrane | 535-557 | Helical | |||
Keywords
- Cellular component
PTM/Processing
Features
Showing features for disulfide bond.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Disulfide bond | 55↔177 | ||||
Disulfide bond | 90↔100 | ||||
Keywords
- PTM
Expression
Gene expression databases
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Domain | 13-195 | Eph LBD | |||
Domain | 316-426 | Fibronectin type-III | |||
Domain | 427-522 | Fibronectin type-III | |||
Domain | 613-876 | Protein kinase | |||
Domain | 905-969 | SAM | |||
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length978
- Mass (Da)109,325
- Last updated2019-12-11 v3
- Checksum8C76636A4539A030
Computationally mapped potential isoform sequences
There is 1 potential isoform mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
A0A1D5QF63 | A0A1D5QF63_MACMU | EPHB1 | 984 |
Keywords
- Technical term