Lineage-specific biology revealed by a finished genome assembly of the mouse.Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X., Bult C.J., Agarwala R., Cherry J.L.[...], Ponting C.P.View abstractCited forNUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]StrainC57BL/6JCategoriesSequencesSourceUniProtKB unreviewed (TrEMBL)PubMedEurope PMCPLoS Biol. 7:E1000112-E1000112 (2009)Cited in99+99+
Modernizing reference genome assemblies.Church D.M., Schneider V.A., Graves T., Auger K., Cunningham F., Bouk N., Chen H.C., Agarwala R., McLaren W.M.[...], Hubbard T.Cited forNUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]StrainC57BL/6JCategoriesSequencesSourceUniProtKB unreviewed (TrEMBL)PubMedEurope PMCPLoS Biol 9:e1001091-e1001091 (2011)Cited in99+
No title available.EnsemblCited forIDENTIFICATIONStrainC57BL/6JSourceUniProtKB unreviewed (TrEMBL)Submission Submitted to UniProtKB (JUN-2024)Cited in99+
Interleukin (IL)-1 receptor-associated kinase (IRAK) requirement for optimal induction of multiple IL-1 signaling pathways and IL-6 production.Kanakaraj P., Schafer P.H., Cavender D.E., Wu Y., Ngo K., Grealish P.F., Wadsworth S.A., Peterson P.A., Siekierka J.J.[...], Fung-Leung W.P.View abstractCategoriesFunctionSourceMGI: 107420PubMedEurope PMCJ Exp Med 187:2073-2079 (1998)Mapped to23
Interleukin-1 receptor-associated kinase gene Il1rak maps to the mouse X chromosome.Centanni J.M., de Miguel M., Gopalan G., Gilbert D.J., Copeland N.G., Jenkins N.A., Donovan P.J.CategoriesSequencesSourceMGI: 107420PubMedEurope PMCMamm Genome 9:340-341 (1998)Mapped to18
Successful determination of platelet lifespan in C3H mice by in vivo biotinylation.Manning K.L., Novinger S., Sullivan P.S., McDonald T.P.View abstractCategoriesFunctionSourceMGI: 107420PubMedEurope PMCLab Anim Sci 46:545-548 (1996)Mapped to15
Developmental and tissue-specific expression of mouse pelle-like protein kinase.Trofimova M., Sprenkle A.B., Green M., Sturgill T.W., Goebl M.G., Harrington M.A.View abstractCategoriesSequencesSourceMGI: 107420PubMedEurope PMCJ. Biol. Chem. 271:17609-17612 (1996)Cited in1Mapped to14
The IRAK1/IRF5 axis initiates IL-12 response by dendritic cells and control of Toxoplasma gondii infection.Pereira M., Ramalho T., Andrade W.A., Durso D.F., Souza M.C., Fitzgerald K.A., Golenbock D.T., Silverman N., Gazzinelli R.T.View abstractSourceMGI: 107420PubMedEurope PMCCell Rep 43:113795-113795 (2024)Mapped to43
Genetic determinants of micronucleus formation in vivo.Adams D.J., Barlas B., McIntyre R.E., Salguero I., van der Weyden L., Barros A., Vicente J.R., Karimpour N., Haider A.[...], White J.K.View abstractSourceMGI: 107420PubMedEurope PMCNature 627:130-136 (2024)Mapped to99+
Phosphorylation of USP20 on Ser334 by IRAK1 promotes IL-1beta-evoked signaling in vascular smooth muscle cells and vascular inflammation.Zhang L., Wu J.H., Jean-Charles P.Y., Murali P., Zhang W., Jazic A., Kaur S., Nepliouev I., Stiber J.A.[...], Shenoy S.K.View abstractCategoriesFunctionSourceMGI: 107420PubMedEurope PMCJ Biol Chem 299:104911-104911 (2023)Mapped to30
Nonhematopoietic IRAK1 drives arthritis via neutrophil chemoattractants.Hoyler T., Bannert B., Andre C., Beck D., Boulay T., Buffet D., Caesar N., Calzascia T., Dawson J.[...], Junt T.View abstractCategoriesFunctionSourceMGI: 107420PubMedEurope PMCJCI Insight 7:e149825-e149825 (2022)Mapped to18
IRAK1-dependent Regnase-1-14-3-3 complex formation controls Regnase-1- mediated mRNA decay.Akaki K., Ogata K., Yamauchi Y., Iwai N., Tse K.M., Hia F., Mochizuki A., Ishihama Y., Mino T., Takeuchi O.View abstractCategoriesFunctionSourceMGI: 107420PubMedEurope PMCElife 10:e71966-e71966 (2021)Mapped to19
UNC93B1 Is Widely Expressed in the Murine CNS and Is Required for Neuroinflammation and Neuronal Injury Induced by MicroRNA <i>let-7b</i>.Klammer M.G., Dzaye O., Wallach T., Kruger C., Gaessler D., Buonfiglioli A., Derkow K., Kettenmann H., Brinkmann M.M., Lehnardt S.View abstractCategoriesFunction, ExpressionSourceMGI: 107420PubMedEurope PMCFront Immunol 12:715774-715774 (2021)Mapped to35
Altered Inflammatory Pathway but Unaffected Liver Fibrosis in Mouse Models of Nonalcoholic Steatohepatitis Involving Interleukin-1 Receptor-Associated Kinase 1 Knockout.Lei Y., Yang T., Shan A., Di W., Dai M., Nan J., Liu D., Cao Y., Jiang X.View abstractCategoriesFunctionSourceMGI: 107420PubMedEurope PMCMed Sci Monit 26:e926187-e926187 (2020)Mapped to18
RNF152 positively regulates TLR/IL-1R signaling by enhancing MyD88 oligomerization.Xiong M.G., Xu Z.S., Li Y.H., Wang S.Y., Wang Y.Y., Ran Y.View abstractCategoriesFunction, InteractionSourceMGI: 107420PubMedEurope PMCEMBO Rep 21:e48860-e48860 (2020)Mapped to27
BAP31 regulates IRAK1-dependent neuroinflammation in microglia.Liu X., Jiao K., Jia C.C., Li G.X., Yuan Q., Xu J.K., Hou Y., Wang B.View abstractCategoriesFunctionSourceMGI: 107420PubMedEurope PMCJ Neuroinflammation 16:281-281 (2019)Mapped to19
Mouse screen reveals multiple new genes underlying mouse and human hearing loss.Ingham N.J., Pearson S.A., Vancollie V.E., Rook V., Lewis M.A., Chen J., Buniello A., Martelletti E., Preite L.[...], Steel K.P.View abstractCategoriesFunctionSourceMGI: 107420PubMedEurope PMCPLoS Biol. 17:E3000194-E3000194 (2019)Cited in4Mapped to99+
Inhibition of IRAK1 Ubiquitination Determines Glucocorticoid Sensitivity for TLR9-Induced Inflammation in Macrophages.Kong F., Liu Z., Jain V.G., Shima K., Suzuki T., Muglia L.J., Starczynowski D.T., Pasare C., Bhattacharyya S.View abstractCategoriesInteractionSourceMGI: 107420PubMedEurope PMCJ Immunol 199:3654-3667 (2017)Mapped to34
Identification of optineurin as an interleukin-1 receptor-associated kinase 1-binding protein and its role in regulation of MyD88-dependent signaling.Tanishima M., Takashima S., Honda A., Yasuda D., Tanikawa T., Ishii S., MaruYama T.View abstractCategoriesInteractionSourceMGI: 107420PubMedEurope PMCJ Biol Chem 292:17250-17257 (2017)Mapped to21
Deletion of interleukin 1 receptor-associated kinase 1 (<i>Irak1</i>) improves glucose tolerance primarily by increasing insulin sensitivity in skeletal muscle.Sun X.J., Kim S.P., Zhang D., Sun H., Cao Q., Lu X., Ying Z., Li L., Henry R.R.[...], Quon M.J.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 107420PubMedEurope PMCJ Biol Chem 292:12339-12350 (2017)Mapped to18
Suppression of IRAK1 or IRAK4 Catalytic Activity, but Not Type 1 IFN Signaling, Prevents Lupus Nephritis in Mice Expressing a Ubiquitin Binding- Defective Mutant of ABIN1.Nanda S.K., Lopez-Pelaez M., Arthur J.S., Marchesi F., Cohen P.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 107420PubMedEurope PMCJ Immunol 197:4266-4273 (2016)Mapped to28
Comprehensive RNAi-based screening of human and mouse TLR pathways identifies species-specific preferences in signaling protein use.Sun J., Li N., Oh K.S., Dutta B., Vayttaden S.J., Lin B., Ebert T.S., De Nardo D., Davis J.[...], Fraser I.D.View abstractCategoriesFunction, InteractionSourceMGI: 107420PubMedEurope PMCSci Signal 9:ra3-ra3 (2016)Mapped to20
T cells down-regulate macrophage TNF production by IRAK1-mediated IL-10 expression and control innate hyperinflammation.Inoue M., Arikawa T., Chen Y.H., Moriwaki Y., Price M., Brown M., Perfect J.R., Shinohara M.L.View abstractCategoriesFunctionSourceMGI: 107420PubMedEurope PMCProc Natl Acad Sci U S A 111:5295-5300 (2014)Mapped to45
IRAK-1 bypasses priming and directly links TLRs to rapid NLRP3 inflammasome activation.Lin K.M., Hu W., Troutman T.D., Jennings M., Brewer T., Li X., Nanda S., Cohen P., Thomas J.A., Pasare C.View abstractCategoriesFunctionSourceMGI: 107420PubMedEurope PMCProc Natl Acad Sci U S A 111:775-780 (2014)Mapped to23
Cellular mosaicism for X-linked polymorphisms and IRAK1 expression presents a distinct phenotype and improves survival following sepsis.Chandra R., Federici S., Nemeth Z.H., Csoka B., Thomas J.A., Donnelly R., Spolarics Z.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 107420PubMedEurope PMCJ Leukoc Biol 95:497-507 (2014)Mapped to18