F7CRQ5 · F7CRQ5_MONDO

Function

function

Cadherins are calcium-dependent cell adhesion proteins.

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentadherens junction
Cellular Componentbicellular tight junction
Cellular Componentcatenin complex
Cellular Componentcytoplasm
Cellular Componentexternal side of plasma membrane
Cellular Componentnuclear membrane
Cellular Componentnucleoplasm
Molecular Functionbeta-catenin binding
Molecular FunctionBMP receptor binding
Molecular Functioncadherin binding
Molecular Functioncalcium ion binding
Molecular Functionfibrinogen binding
Molecular Functionprotein phosphatase binding
Molecular Functionprotein tyrosine kinase binding
Molecular Functiontransmembrane transporter binding
Molecular Functionvascular endothelial growth factor receptor 2 binding
Biological Processadherens junction organization
Biological Processbicellular tight junction assembly
Biological Processblood vessel endothelial cell migration
Biological Processblood vessel maturation
Biological Processcalcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules
Biological Processcell migration
Biological Processcell morphogenesis
Biological Processcell-cell adhesion mediated by cadherin
Biological Processcell-cell junction assembly
Biological Processendothelial cell morphogenesis
Biological Processhomophilic cell adhesion via plasma membrane adhesion molecules
Biological Processintracellular calcium ion homeostasis
Biological Processnegative regulation of cell population proliferation
Biological Processnegative regulation of endothelial cell apoptotic process
Biological Processnegative regulation of inflammatory response
Biological Processnegative regulation of microtubule polymerization
Biological Processpositive regulation of angiogenesis
Biological Processpositive regulation of BMP signaling pathway
Biological Processpositive regulation of cell migration
Biological Processpositive regulation of establishment of endothelial barrier
Biological Processpositive regulation of gene expression
Biological Processpositive regulation of protein dephosphorylation
Biological Processpositive regulation of protein-containing complex assembly
Biological Processprotein localization to bicellular tight junction
Biological Processregulation of establishment of cell polarity
Biological Processregulation of protein phosphorylation
Biological Processregulation of vascular permeability
Biological Processtransforming growth factor beta receptor signaling pathway

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Cadherin-5
  • Alternative names
    • Vascular endothelial cadherin

Gene names

    • Name
      CDH5

Organism names

Accessions

  • Primary accession
    F7CRQ5

Proteomes

Subcellular Location

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane534-554Helical

Keywords

PTM/Processing

Keywords

Expression

Gene expression databases

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain, region.

Type
IDPosition(s)Description
Domain11-83Cadherin
Domain84-190Cadherin
Domain191-305Cadherin
Domain306-412Cadherin
Domain412-520Cadherin
Region599-619Disordered

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    722
  • Mass (Da)
    80,627
  • Last updated
    2019-12-11 v2
  • Checksum
    615CDFED0386B837
ITSSVNRKNARYVLKGPEAGKGKLFGVNEHTGDVYAFERLDREKKSEYYLTAYIVDKDTNQNLEPPSNFTIKVHDVNDNVPEFAQRLFNGSVPEMSAVGTSVTRVTAVDADDPTVLGHASVTYNIIQGREYFTIDGSGTIFTTVHNLDREKQSKYEIVVEAKDGPGLHGESSTATVVITVSDINDNFPIFTQTNYKFVVPEDIRVGSSLGSLTVEDPDEPQNRMTKYSIVQGEYRDTFIIELDASRNEGIIKPMKPLDYENIKEYSFSIEATDPTINLRYLNKAPPKNLALVYINVTDVDEPPVFSQPFYHFKMPENQRVNSVGSVLAKDPDAAQWNIGYSIRKTSDRGQFFRITKQGYISNIKELDREIYPWYNLTIEAKEMKPQGNANGLESIVQVYIEILDENDNAPEIPHPDDAKVCENAAPGTLVTRILAIDKDITPPDVKFKYSLIKEDSNFTLTENRDNSANITVKYGQFDRERAKVHYLPVVIADNGRPSLTGTTTLTITVCKCNDRGEPTFCEEPEMQVGVSIQALVAIFLCILTIVVITVLIVLRRRLRKQDRAQGKNVAEIHEQLVTYDEEGGGEMDTNSYDVSVLNSARKSSGKPPGGKPPRPALDTRPSLYAQIQKPPRPAHPQAVTGEMAVMIEVKKDEADHDGGGPPYDTLHIYGYEGAESIAESLSSLVTDSSDSDIDYDFLNDWGPRFKMLAELYGTEPSHELIY

Keywords

Genome annotation databases

Similar Proteins

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