F7CIP8 · F7CIP8_MOUSE

  • Protein
    Prenylcysteine oxidase 1
  • Gene
    Pcyox1
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Evidence at protein level
  • Annotation score
    2/5

Function

function

Prenylcysteine oxidase that cleaves the thioether bond of prenyl-L-cysteines, such as farnesylcysteine and geranylgeranylcysteine. Only active against free prenylcysteines and not prenylcysteine residues within prenylated proteins or peptides. Involved in the final step in the degradation of prenylated proteins, by degrading prenylcysteines after the protein has been degraded.

Catalytic activity

Cofactor

FAD (UniProtKB | Rhea| CHEBI:57692 )

GO annotations

AspectTerm
Cellular Componentlysosome
Molecular Functionprenylcysteine oxidase activity
Biological Processprenylcysteine catabolic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Prenylcysteine oxidase 1
  • EC number

Gene names

    • Name
      Pcyox1

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • C57BL/6J
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Glires > Rodentia > Myomorpha > Muroidea > Muridae > Murinae > Mus > Mus

Accessions

  • Primary accession
    F7CIP8

Proteomes

Organism-specific databases

Subcellular Location

Keywords

  • Cellular component

PTM/Processing

Expression

Gene expression databases

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain70-196Prenylcysteine lyase

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Fragment
  • Length
    197
  • Mass (Da)
    22,305
  • Last updated
    2011-07-27 v1
  • MD5 Checksum
    4F32B5B69E013E607F423BFDF540A462
XRYQSHDYAFSSVEKLMHAIGGDDYVRLLNQTLRENLKKAGFSETFLNEMIAPVMKVNYGQSTDINAFVGNPTKMYEVVYKTGSETHSDFYDIVLVAAPLNRKMSNITFRNFDPPIEEFNDPYQQLVTTFIKGELNSTLFSSRPKDQFGLSAILVTDDSDMFINSLSIVASVRQKEGPPPAVDGMHVWKTFSRDILT

Computationally mapped potential isoform sequences

There are 3 potential isoforms mapped to this entry

View all
EntryEntry nameGene nameLength
Q9CQF9PCYOX_MOUSEPcyox1505
A0A0N4SWD3A0A0N4SWD3_MOUSEPcyox1148
D3Z275D3Z275_MOUSEPcyox1214

Features

Showing features for non-terminal residue.

TypeIDPosition(s)Description
Non-terminal residue1
Non-terminal residue197

Keywords

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
This website requires cookies, and the limited processing of your personal data in order to function. By using the site you are agreeing to this as outlined in our Privacy Notice.
Help