Lineage-specific biology revealed by a finished genome assembly of the mouse.Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X., Bult C.J., Agarwala R., Cherry J.L.[...], Ponting C.P.View abstractCited forNUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]StrainC57BL/6JCategoriesSequencesSourceUniProtKB unreviewed (TrEMBL)PubMedEurope PMCPLoS Biol. 7:E1000112-E1000112 (2009)Cited in99+99+
A tissue-specific atlas of mouse protein phosphorylation and expression.Huttlin E.L., Jedrychowski M.P., Elias J.E., Goswami T., Rad R., Beausoleil S.A., Villen J., Haas W., Sowa M.E., Gygi S.P.View abstractCited forIDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]CategoriesSequencesSourceUniProtKB unreviewed (TrEMBL)PubMedEurope PMCCell 143:1174-1189 (2010)Cited in99+99+Mapped to6
No title available.EnsemblCited forIDENTIFICATIONStrainC57BL/6JSourceUniProtKB unreviewed (TrEMBL)Submission Submitted to UniProtKB (JUN-2011)Cited in99+
SHLD1 is dispensable for 53BP1-dependent V(D)J recombination but critical for productive class switch recombination.Vincendeau E., Wei W., Zhang X., Planchais C., Yu W., Lenden-Hasse H., Cokelaer T., Pipoli da Fonseca J., Mouquet H.[...], Deriano L.View abstractCategoriesFunctionSourceMGI: 1922820PubMedEurope PMCNat Commun 13:3707-3707 (2022)Mapped to29
An XRCC4 mutant mouse, a model for human X4 syndrome, reveals interplays with Xlf, PAXX, and ATM in lymphoid development.Roch B., Abramowski V., Etienne O., Musilli S., David P., Charbonnier J.B., Callebaut I., Boussin F.D., de Villartay J.P.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 1922820PubMedEurope PMCElife 10:e69353-e69353 (2021)Mapped to15
Leaky severe combined immunodeficiency in mice lacking non-homologous end joining factors XLF and MRI.Castaneda-Zegarra S., Zhang Q., Alirezaylavasani A., Fernandez-Berrocal M., Yao R., Oksenych V.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 1922820PubMedEurope PMCAging (Albany NY) 12:23578-23597 (2020)Mapped to21
ERCC6L2 promotes DNA orientation-specific recombination in mammalian cells.Liu X., Liu T., Shang Y., Dai P., Zhang W., Lee B.J., Huang M., Yang D., Wu Q.[...], Meng F.L.View abstractCategoriesFunctionSourceMGI: 1922820PubMedEurope PMCCell Res 30:732-744 (2020)Mapped to11
An <i>in vivo</i> study of the impact of deficiency in the DNA repair proteins PAXX and XLF on development and maturation of the hemolymphoid system.Musilli S., Abramowski V., Roch B., de Villartay J.P.View abstractCategoriesInteractionSourceMGI: 1922820PubMedEurope PMCJ Biol Chem 295:2398-2406 (2020)Mapped to4
XLF and H2AX function in series to promote replication fork stability.Chen B.R., Quinet A., Byrum A.K., Jackson J., Berti M., Thangavel S., Bredemeyer A.L., Hindi I., Mosammaparast N.[...], Sleckman B.P.View abstractCategoriesFunction, InteractionSourceMGI: 1922820PubMedEurope PMCJ Cell Biol 218:2113-2123 (2019)Mapped to11
Cernunnos/Xlf Deficiency Results in Suboptimal V(D)J Recombination and Impaired Lymphoid Development in Mice.Roch B., Abramowski V., Chaumeil J., de Villartay J.P.View abstractCategoriesFunctionSourceMGI: 1922820PubMedEurope PMCFront Immunol 10:443-443 (2019)Mapped to29
Synthetic lethality between DNA repair factors Xlf and Paxx is rescued by inactivation of Trp53.Castaneda-Zegarra S., Xing M., Gago-Fuentes R., Saeterstad S., Oksenych V.View abstractCategoriesFunctionSourceMGI: 1922820PubMedEurope PMCDNA Repair (Amst) 73:164-169 (2019)Mapped to99+
SOX17 regulates uterine epithelial-stromal cross-talk acting via a distal enhancer upstream of Ihh.Wang X., Li X., Wang T., Wu S.P., Jeong J.W., Kim T.H., Young S.L., Lessey B.A., Lanz R.B.[...], DeMayo F.J.View abstractCategoriesFunctionSourceMGI: 1922820PubMedEurope PMCNat Commun 9:4421-4421 (2018)Mapped to41
MRI is a DNA damage response adaptor during classical non-homologous end joining.Hung P.J., Johnson B., Chen B.R., Byrum A.K., Bredemeyer A.L., Yewdell W.T., Johnson T.E., Lee B.J., Deivasigamani S.[...], Sleckman B.P.View abstractCategoriesFunction, InteractionSourceMGI: 1922820PubMedEurope PMCMol. Cell 71:332-342 (2018)Cited in9Mapped to24
C-NHEJ without indels is robust and requires synergistic function of distinct XLF domains.Bhargava R., Sandhu M., Muk S., Lee G., Vaidehi N., Stark J.M.View abstractCategoriesFunctionSourceMGI: 1922820PubMedEurope PMCNat Commun 9:2484-2484 (2018)Mapped to2
PAXX and Xlf interplay revealed by impaired CNS development and immunodeficiency of double KO mice.Abramowski V., Etienne O., Elsaid R., Yang J., Berland A., Kermasson L., Roch B., Musilli S., Moussu J.P.[...], de Villartay J.P.View abstractCategoriesFunction, InteractionSourceMGI: 1922820PubMedEurope PMCCell Death Differ. 25:444-452 (2018)Cited in2Mapped to10
Composition and dosage of a multipartite enhancer cluster control developmental expression of Ihh (Indian hedgehog).Will A.J., Cova G., Osterwalder M., Chan W.L., Wittler L., Brieske N., Heinrich V., de Villartay J.P., Vingron M.[...], Mundlos S.View abstractCategoriesFunction, SequencesSourceMGI: 1922820PubMedEurope PMCNat Genet 49:1539-1545 (2017)Mapped to66
Synthetic lethality between murine DNA repair factors XLF and DNA-PKcs is rescued by inactivation of Ku70.Xing M., Bjoras M., Daniel J.A., Alt F.W., Oksenych V.View abstractCategoriesFunctionSourceMGI: 1922820PubMedEurope PMCDNA Repair (Amst) 57:133-138 (2017)Mapped to30
Contribution of canonical nonhomologous end joining to chromosomal rearrangements is enhanced by ATM kinase deficiency.Bhargava R., Carson C.R., Lee G., Stark J.M.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 1922820PubMedEurope PMCProc Natl Acad Sci U S A 114:728-733 (2017)Mapped to20
PAXX promotes KU accumulation at DNA breaks and is essential for end- joining in XLF-deficient mice.Liu X., Shao Z., Jiang W., Lee B.J., Zha S.View abstractCategoriesFunctionSourceMGI: 1922820PubMedEurope PMCNat. Commun. 8:13816-13816 (2017)Cited in2Mapped to15
Synthetic lethality between PAXX and XLF in mammalian development.Balmus G., Barros A.C., Wijnhoven P.W., Lescale C., Hasse H.L., Boroviak K., le Sage C., Doe B., Speak A.O.[...], Jackson S.P.View abstractCategoriesFunctionSourceMGI: 1922820PubMedEurope PMCGenes Dev. 30:2152-2157 (2016)Cited in2Mapped to16
PAXX and XLF DNA repair factors are functionally redundant in joining DNA breaks in a G1-arrested progenitor B-cell line.Kumar V., Alt F.W., Frock R.L.View abstractCategoriesFunctionSourceMGI: 1922820PubMedEurope PMCProc. Natl. Acad. Sci. U.S.A. 113:10619-10624 (2016)Cited in2Mapped to2
RAG2 and XLF/Cernunnos interplay reveals a novel role for the RAG complex in DNA repair.Lescale C., Abramowski V., Bedora-Faure M., Murigneux V., Vera G., Roth D.B., Revy P., de Villartay J.P., Deriano L.View abstractCategoriesFunctionSourceMGI: 1922820PubMedEurope PMCNat Commun 7:10529-10529 (2016)Mapped to30
Akt-mediated phosphorylation of XLF impairs non-homologous end-joining DNA repair.Liu P., Gan W., Guo C., Xie A., Gao D., Guo J., Zhang J., Willis N., Su A.[...], Wei W.View abstractCategoriesFunctionSourceMGI: 1922820PubMedEurope PMCMol Cell 57:648-661 (2015)Mapped to3
Hematopoietic stem cell dysfunction underlies the progressive lymphocytopenia in XLF/Cernunnos deficiency.Avagyan S., Churchill M., Yamamoto K., Crowe J.L., Li C., Lee B.J., Zheng T., Mukherjee S., Zha S.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 1922820PubMedEurope PMCBlood 124:1622-1625 (2014)Mapped to11
Opposing roles for 53BP1 during homologous recombination.Kakarougkas A., Ismail A., Klement K., Goodarzi A.A., Conrad S., Freire R., Shibata A., Lobrich M., Jeggo P.A.View abstractCategoriesFunctionSourceMGI: 1922820PubMedEurope PMCNucleic Acids Res 41:9719-9731 (2013)Mapped to38