F7BG82 · F7BG82_MACMU
- ProteinARF GTPase-activating protein GIT2 isoform 1
- GeneGIT2
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids709 (go to sequence)
- Protein existenceEvidence at transcript level
- Annotation score1/5
Function
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Molecular Function | GTPase activator activity | |
Molecular Function | metal ion binding | |
Biological Process | brain development | |
Biological Process | regulation of ARF protein signal transduction |
Keywords
- Ligand
Names & Taxonomy
Protein names
- Submitted names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Primates > Haplorrhini > Catarrhini > Cercopithecidae > Cercopithecinae > Macaca
Accessions
- Primary accessionF7BG82
- Secondary accessions
Proteomes
Organism-specific databases
Expression
Gene expression databases
Structure
Family & Domains
Features
Showing features for domain, repeat, region, compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 1-124 | Arf-GAP | ||||
Sequence: MSKRLRSSEVCADCSGPDPSWASVNRGTFICDECCSVHRSLGRHISQVRHLKHTPWPPTLLQMVETLYNNGANSIWEHSLLDPASIMSGRRKANPQDKVHPNKAEFIRAKYQMLAFVHRLPCRD | ||||||
Repeat | 166-198 | ANK | ||||
Sequence: KGNTPLHVASKAGQILQAELLAVYGADPGTQDS | ||||||
Region | 380-489 | Disordered | ||||
Sequence: HSIESQDNDQPDYDSVASDEDTDLETTASKANRQKLQTLQSENSNLRKQATTNVYQVQTGSEYTDTSNHSSLKRRPSARGSRPMSMYETGSGQKPYLPMGEASRPEESRT | ||||||
Compositional bias | 408-453 | Polar residues | ||||
Sequence: SKANRQKLQTLQSENSNLRKQATTNVYQVQTGSEYTDTSNHSSLKR | ||||||
Compositional bias | 505-522 | Polar residues | ||||
Sequence: TSSSSLPSFPSTLSWSRD | ||||||
Region | 505-592 | Disordered | ||||
Sequence: TSSSSLPSFPSTLSWSRDESARRASRLEKQNSTPESDYDNTPNDMEPDGMGSSRKGRQRSMVWPGDGLVPDTAEPHVAPSPTLPSTED | ||||||
Compositional bias | 523-537 | Basic and acidic residues | ||||
Sequence: ESARRASRLEKQNST |
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length709
- Mass (Da)78,942
- Last updated2019-12-11 v3
- Checksum6D4F4CBDC195CC42
Computationally mapped potential isoform sequences
There are 7 potential isoforms mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
F7BFQ7 | F7BFQ7_MACMU | GIT2 | 740 | ||
A0A5F7ZJ47 | A0A5F7ZJ47_MACMU | GIT2 | 647 | ||
F6UCN1 | F6UCN1_MACMU | GIT2 | 676 | ||
F7BFP0 | F7BFP0_MACMU | GIT2 | 471 | ||
F7BFP7 | F7BFP7_MACMU | GIT2 | 596 | ||
H9EU99 | H9EU99_MACMU | GIT2 | 729 | ||
A0A5F7ZA17 | A0A5F7ZA17_MACMU | GIT2 | 631 |
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 408-453 | Polar residues | ||||
Sequence: SKANRQKLQTLQSENSNLRKQATTNVYQVQTGSEYTDTSNHSSLKR | ||||||
Compositional bias | 505-522 | Polar residues | ||||
Sequence: TSSSSLPSFPSTLSWSRD | ||||||
Compositional bias | 523-537 | Basic and acidic residues | ||||
Sequence: ESARRASRLEKQNST |
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
JU337338 EMBL· GenBank· DDBJ | AFE81089.1 EMBL· GenBank· DDBJ | mRNA |