F7AX08 · F7AX08_CIOIN
- ProteinMitogen-activated protein kinase kinase kinase kinase
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids866 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Serine/threonine kinase that plays a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway.
Catalytic activity
- ATP + L-seryl-[protein] = ADP + H+ + O-phospho-L-seryl-[protein]
Cofactor
Features
Showing features for binding site, active site.
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | ATP binding | |
Molecular Function | MAP kinase kinase kinase kinase activity | |
Molecular Function | protein serine kinase activity |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameMitogen-activated protein kinase kinase kinase kinase
- EC number
Organism names
- Taxonomic lineageEukaryota > Metazoa > Chordata > Tunicata > Ascidiacea > Phlebobranchia > Cionidae > Ciona
Accessions
- Primary accessionF7AX08
Proteomes
Structure
Family & Domains
Features
Showing features for domain, region, compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 16-273 | Protein kinase | ||||
Sequence: FELLQRVGSGTYGDVYKARHNVSKELAAIKVIKLEPGDDFSIIQQEIIMMKDCKHDNIVAYFGSYLRRDKLWIAMEYCGGGSMQDIYHITGPLDEKLIAYVCRETLKGLAYLHSKGKMHRDIKGANILLTDEGSVKLADFGVSAQITQTIAKRKSFIGTPYWMAPEVAAVERKGGYNQQCDVWAVGITAIEFGELQPPMFDLHPMRALFLMSKSSFQPPKLKDKQKWSTDFHSFVKAALTKNPRRRPSSEKMLQHSFV | ||||||
Region | 290-330 | Disordered | ||||
Sequence: SREPQIGEDEDDEDELISVIPKRRIQSSRPKEERQGKTKSE | ||||||
Compositional bias | 305-329 | Basic and acidic residues | ||||
Sequence: LISVIPKRRIQSSRPKEERQGKTKS | ||||||
Region | 390-481 | Disordered | ||||
Sequence: GAQPNALGPPSRPPKDSNLANAPSRPPKPPPYHINGGAFEDDPPLVPPRRRNSPALIGALVDPASGRPPVRPMSRALNGASQDSGLLGRPTP | ||||||
Domain | 529-836 | CNH | ||||
Sequence: PLKINCASSWVHPDSHDQYILFGADEGIYTLNLHELHENTMEQLFPRKCVWLYVISNVLMSISGNRTPQLYSHNLVGLHENAQRTQRIHLPEKMVPRRFAVSTKVPDTKNCQRCSVVRNQYNGHKYLCAALQQAVVLLQWYEPMNKFLLIKQFDYPLPHPLRVFELLVTPDAEYPLVCYGDNKDSGPLSVYHLNTINLNTSSSWFSDQGQSGTQLAVVNVTQLEKDTLLICLERDVKIISLSGKLKSSRKLASELHFDFVTKNIVCLQDSILAFHEHGMQGRSFRNNEVTQEICDRSRIFRLLSCYRV |
Sequence similarities
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length866
- Mass (Da)97,582
- Last updated2012-04-18 v2
- Checksum7EC8634F6DE46747
Computationally mapped potential isoform sequences
There is 1 potential isoform mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
F7AX97 | F7AX97_CIOIN | 898 |
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 305-329 | Basic and acidic residues | ||||
Sequence: LISVIPKRRIQSSRPKEERQGKTKS |
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
EAAA01002976 EMBL· GenBank· DDBJ | - | Genomic DNA | No translation available. |