F7AX08 · F7AX08_CIOIN

Function

function

Serine/threonine kinase that plays a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway.

Catalytic activity

Cofactor

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Features

Showing features for binding site, active site.

TypeIDPosition(s)Description
Binding site22-30ATP (UniProtKB | ChEBI)
Binding site45ATP (UniProtKB | ChEBI)
Active site136Proton acceptor

GO annotations

AspectTerm
Molecular FunctionATP binding
Molecular FunctionMAP kinase kinase kinase kinase activity
Molecular Functionprotein serine kinase activity

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Mitogen-activated protein kinase kinase kinase kinase
  • EC number

Organism names

Accessions

  • Primary accession
    F7AX08

Proteomes

Family & Domains

Features

Showing features for domain, region, compositional bias.

TypeIDPosition(s)Description
Domain16-273Protein kinase
Region290-330Disordered
Compositional bias305-329Basic and acidic residues
Region390-481Disordered
Domain529-836CNH

Sequence similarities

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    866
  • Mass (Da)
    97,582
  • Last updated
    2012-04-18 v2
  • Checksum
    7EC8634F6DE46747
MNPSADISRKNPQDDFELLQRVGSGTYGDVYKARHNVSKELAAIKVIKLEPGDDFSIIQQEIIMMKDCKHDNIVAYFGSYLRRDKLWIAMEYCGGGSMQDIYHITGPLDEKLIAYVCRETLKGLAYLHSKGKMHRDIKGANILLTDEGSVKLADFGVSAQITQTIAKRKSFIGTPYWMAPEVAAVERKGGYNQQCDVWAVGITAIEFGELQPPMFDLHPMRALFLMSKSSFQPPKLKDKQKWSTDFHSFVKAALTKNPRRRPSSEKMLQHSFVTQDGLVAKLGSDMLKRSREPQIGEDEDDEDELISVIPKRRIQSSRPKEERQGKTKSEAILGDIQFQPPVTRETDLEFVSIKIMPTNEFSFHRRMTRDGLQRKFLAKKPRQYGVEYFGAQPNALGPPSRPPKDSNLANAPSRPPKPPPYHINGGAFEDDPPLVPPRRRNSPALIGALVDPASGRPPVRPMSRALNGASQDSGLLGRPTPLMAVAKPPLAEPEDDDSTTSSQNVVNGLPPTPKVHMGACFTKVFNGCPLKINCASSWVHPDSHDQYILFGADEGIYTLNLHELHENTMEQLFPRKCVWLYVISNVLMSISGNRTPQLYSHNLVGLHENAQRTQRIHLPEKMVPRRFAVSTKVPDTKNCQRCSVVRNQYNGHKYLCAALQQAVVLLQWYEPMNKFLLIKQFDYPLPHPLRVFELLVTPDAEYPLVCYGDNKDSGPLSVYHLNTINLNTSSSWFSDQGQSGTQLAVVNVTQLEKDTLLICLERDVKIISLSGKLKSSRKLASELHFDFVTKNIVCLQDSILAFHEHGMQGRSFRNNEVTQEICDRSRIFRLLSCYRVIVLESKPTDNPKELSNLYILAGHEDMSSVF

Computationally mapped potential isoform sequences

There is 1 potential isoform mapped to this entry

View all
EntryEntry nameGene nameLength
F7AX97F7AX97_CIOIN898

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias305-329Basic and acidic residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
EAAA01002976
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.
FeedbackHelp