F6YJL0 · F6YJL0_ORNAN

Function

Catalytic activity

  • (E)-hex-2-en-1-ol + NADP+ = (E)-hex-2-enal + NADPH + H+
  • (E,E)-2,4-hexadien-1-ol + NADP+ = (E,E)-2,4-hexadienal + NADPH + H+
  • 1-hexadecanoyl-2-(5-oxopentanoyl)-sn-glycero-3-phosphocholine + NADPH + H+ = 1-hexadecanoyl-2-(5-hydroxypentanoyl)-sn-glycero-3-phosphocholine + NADP+
  • 1-hexadecanoyl-2-(5-oxopentanoyl)-sn-glycero-3-phosphoethanolamine + NADPH + H+ = 1-hexadecanoyl-2-(5-hydroxypentanoyl)-sn-glycero-3-phosphoethanolamine + NADP+
  • 1-hexadecanoyl-2-(7-oxoheptanoyl)-sn-glycero-3-phosphocholine + NADPH + H+ = 1-hexadecanoyl-2-(7-hydroxyheptanoyl)-sn-glycero-3-phosphocholine + NADP+
  • 1-hexadecanoyl-2-(9-oxononanoyl)-sn-glycero-3-phosphocholine + NADPH + H+ = 1-hexadecanoyl-2-(9-hydroxynonanoyl)-sn-glycero-3-phosphocholine + NADP+
  • 13-cis-retinol + NADP+ = 13-cis-retinal + NADPH + H+
  • 9-cis-retinol + NADP+ = 9-cis-retinal + NADPH + H+
  • prenol + NADP+ = 3-methyl-2-butenal + NADPH + H+
  • prostaglandin F2alpha + NADP+ = prostaglandin H2 + NADPH + H+
  • a 4-hydroxynonen-1-ol + NADP+ = a 4-hydroxynonenal + NADPH + H+
  • all-trans-retinol + NADP+ = all-trans-retinal + NADPH + H+
    EC:1.1.1.300 (UniProtKB | ENZYME | Rhea)
  • an alditol + NADP+ = an aldose + NADPH + H+
    EC:1.1.1.21 (UniProtKB | ENZYME | Rhea)

Features

Showing features for active site, site, binding site.

Type
IDPosition(s)Description
Active site49Proton donor
Site78Lowers pKa of active site Tyr
Binding site111substrate

GO annotations

AspectTerm
Cellular Componentcytosol
Molecular Functionaldose reductase (NADPH) activity

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Aldo-keto reductase family 1 member B1
  • EC number
  • Alternative names
    • Aldose reductase

Gene names

    • Name
      LOC100075884

Organism names

Accessions

  • Primary accession
    F6YJL0

Proteomes

Subcellular Location

PTM/Processing

Keywords

Expression

Gene expression databases

Interaction

Subunit

Monomer.

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain16-302NADP-dependent oxidoreductase

Sequence similarities

Belongs to the aldo/keto reductase family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    327
  • Mass (Da)
    37,082
  • Last updated
    2020-12-02 v3
  • Checksum
    07D0EEF8C9785C2E
MATFVELNTEAKMPTVGLGTWKSSPGQVAEAVKVAIDTGYRHFDCAHVYRNENEVGDAIRQKIKEGVVKREDLFIVSKLWSTFHEKHLVKGACQKSLSELQLDYLDLYLIHWPIGFKAGEVFMPLDEEGHIISSNTSLVDTWEAMEELVDAGLVKAIGVSNFNHEQIERILNKPGLKYLPATNQVECHPYLTQVKLINYCQSKGISVTAYSPFGSPDRPWSCPVSRHVPVRAKPEDPSLLDDSKIKEIAAKHKKTSAQVLIRFHIQRNVIAIPKSVTPQRIVENFQVFDFELSKEEMGTILSFNRNWRACGIQANENHKDYPFKAEY

Computationally mapped potential isoform sequences

There is 1 potential isoform mapped to this entry

View all
EntryEntry nameGene nameLength
A0A6I8PG89A0A6I8PG89_ORNANLOC100075884316

Keywords

Genome annotation databases

Similar Proteins

Disclaimer

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