F6YJL0 · F6YJL0_ORNAN
- ProteinAldo-keto reductase family 1 member B1
- GeneLOC100075884
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids327 (go to sequence)
- Protein existenceInferred from homology
- Annotation score4/5
Function
Catalytic activity
- (E)-hex-2-en-1-ol + NADP+ = (E)-hex-2-enal + NADPH + H+
- (E,E)-2,4-hexadien-1-ol + NADP+ = (E,E)-2,4-hexadienal + NADPH + H+
- 1-hexadecanoyl-2-(5-oxopentanoyl)-sn-glycero-3-phosphocholine + NADPH + H+ = 1-hexadecanoyl-2-(5-hydroxypentanoyl)-sn-glycero-3-phosphocholine + NADP+
- 1-hexadecanoyl-2-(5-oxopentanoyl)-sn-glycero-3-phosphoethanolamine + NADPH + H+ = 1-hexadecanoyl-2-(5-hydroxypentanoyl)-sn-glycero-3-phosphoethanolamine + NADP+
- 1-hexadecanoyl-2-(7-oxoheptanoyl)-sn-glycero-3-phosphocholine + NADPH + H+ = 1-hexadecanoyl-2-(7-hydroxyheptanoyl)-sn-glycero-3-phosphocholine + NADP+
- 1-hexadecanoyl-2-(9-oxononanoyl)-sn-glycero-3-phosphocholine + NADPH + H+ = 1-hexadecanoyl-2-(9-hydroxynonanoyl)-sn-glycero-3-phosphocholine + NADP+
- 13-cis-retinol + NADP+ = 13-cis-retinal + NADPH + H+
- 9-cis-retinol + NADP+ = 9-cis-retinal + NADPH + H+
- prenol + NADP+ = 3-methyl-2-butenal + NADPH + H+
- prostaglandin F2alpha + NADP+ = prostaglandin H2 + NADPH + H+
- a 4-hydroxynonen-1-ol + NADP+ = a 4-hydroxynonenal + NADPH + H+
Features
Showing features for active site, site, binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Active site | 49 | Proton donor | |||
Site | 78 | Lowers pKa of active site Tyr | |||
Binding site | 111 | substrate | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytosol | |
Molecular Function | aldose reductase (NADPH) activity |
Keywords
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameAldo-keto reductase family 1 member B1
- EC number
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Monotremata > Ornithorhynchidae > Ornithorhynchus
Accessions
- Primary accessionF6YJL0
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
PTM/Processing
Keywords
- PTM
Expression
Gene expression databases
Interaction
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Domain | 16-302 | NADP-dependent oxidoreductase | |||
Sequence similarities
Belongs to the aldo/keto reductase family.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length327
- Mass (Da)37,082
- Last updated2020-12-02 v3
- Checksum07D0EEF8C9785C2E
Computationally mapped potential isoform sequences
There is 1 potential isoform mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
A0A6I8PG89 | A0A6I8PG89_ORNAN | LOC100075884 | 316 |
Keywords
- Technical term