F6WYU9 · F6WYU9_CIOIN

Function

function

DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability.

Catalytic activity

Cofactor

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Features

Showing features for binding site, dna binding.

160750100150200250300350400450500550600
Type
IDPosition(s)Description
Binding site216-223ATP (UniProtKB | ChEBI)
DNA binding566-585

GO annotations

AspectTerm
Cellular Componentmitochondrion
Cellular Componentnucleus
Cellular Componentreplication fork
Molecular Function5'-3' DNA helicase activity
Molecular FunctionATP binding
Molecular FunctionATP hydrolysis activity
Molecular FunctionDNA binding
Biological ProcessDNA duplex unwinding
Biological ProcessDNA recombination
Biological ProcessDNA repair
Biological ProcessDNA replication
Biological Processmitochondrial genome maintenance
Biological Processtelomere maintenance

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    ATP-dependent DNA helicase PIF1
  • EC number
  • Alternative names
    • DNA repair and recombination helicase PIF1

Gene names

    • Name
      PIF1

Organism names

Accessions

  • Primary accession
    F6WYU9

Proteomes

Subcellular Location

Keywords

Interaction

Subunit

Monomer.

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain458-493DNA helicase Pif1-like 2B

Sequence similarities

Belongs to the helicase family. PIF1 subfamily.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    607
  • Mass (Da)
    67,873
  • Last updated
    2011-07-27 v1
  • MD5 Checksum
    613D1C752D8033BF05012BDEB7D20426
KVLAMSENTSITCNICVESISGSKNVVKRETIKNGNLTLWRNEQKEIVLLLTRSKKETKFVLYDIQIHCKFMKEGKGSITLTNHNVSFLLSNCPPKNLRQFFKVLSVKMTRFKQQHNKITDRKKLLMTSQINEISPLNEGDIASVNKMRQTIATSKLADGINRKRKLELTTNNQTMKNAGPPPKKTMLTLKTENLNSDQKKVINLVKQGRNLFFTGSAGTGKSFLLRHIVGILPPGQTAVTASTGVAACHIGGVTLHSFAGIGSGSASIENCIQLAKSRPAVVKQWKACRHLIIDEISMISGDFFDKIEAVARAVRGSMDPFGGIQLILCGDFFQLPPVSKGKETVKLCFQSKSWQPCVDVCWELKHVYRQTDTKFIQMLQDIRIGRCTAKIEEVLKATKLNKTENNGILATQLCTHKENVQLCNKNQLEKLPSDPIVYEAQDSTTAFTDIIDKMLPDTKIITLKKGAQVMLNKNLNVGKGMVNGARGIVTGFTKSEQPLPIVRFLNGDEHTIKLECWTVKVVCDLIVVRKQIPLKLAWAISIHKSQGMSLDCVEMSLSRVFECGQAYVALSRARNLEGLRVLDFQASCVRSNVHVLRFYRRIRQEQ

Keywords

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.
Help