F6W8R9 · F6W8R9_MOUSE
- ProteinSpectrin repeat containing, nuclear envelope 2
- GeneSyne2
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids1644 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score2/5
Publications for F6W8R9
Lack of a Retinal Phenotype in a Syne-2/Nesprin-2 Knockout Mouse Model.
- CategoriesInteraction, Subcellular Location
- SourceMGI: 2449316
Depletion of Nesprin-2 is associated with an embryonic lethal phenotype in mice.
- CategoriesFunction, Phenotypes & Variants
- SourceMGI: 2449316
Functional analyses of Pericentrin and Syne-2 interaction in ciliogenesis.
- CategoriesInteraction, Subcellular Location
- SourceMGI: 2449316
STEF/TIAM2-mediated Rac1 activity at the nuclear envelope regulates the perinuclear actin cap.
- CategoriesInteraction, Subcellular Location
- SourceMGI: 2449316
Coiled-coil domains of SUN proteins as intrinsic dynamic regulators.
- CategoryStructure
- SourceMGI: 2449316
Nesprins anchor kinesin-1 motors to the nucleus to drive nuclear distribution in muscle cells.
- CategoriesInteraction, Subcellular Location
- SourceMGI: 2449316
FHOD1 interaction with nesprin-2G mediates TAN line formation and nuclear movement.
- CategoryInteraction
- SourceMGI: 2449316
Samp1 is a component of TAN lines and is required for nuclear movement.
- CategoryInteraction
- SourceMGI: 2449316
Linear arrays of nuclear envelope proteins harness retrograde actin flow for nuclear movement.
- CategorySubcellular Location
- SourceMGI: 2449316
Nesprin-2 Giant (NUANCE) maintains nuclear envelope architecture and composition in skin.
- CategorySubcellular Location
- SourceMGI: 2449316
Syne-1 and Syne-2 play crucial roles in myonuclear anchorage and motor neuron innervation.
- CategoriesInteraction, Subcellular Location
- SourceMGI: 2449316
Nesprin-2 is a multi-isomeric protein that binds lamin and emerin at the nuclear envelope and forms a subcellular network in skeletal muscle.
- CategorySubcellular Location
- SourceMGI: 2449316
Syne-1, a dystrophin- and Klarsicht-related protein associated with synaptic nuclei at the neuromuscular junction.
- CategorySubcellular Location
- SourceMGI: 2449316