F6VX93 · F6VX93_HUMAN

  • Protein
    VPS53 subunit of GARP complex
  • Gene
    VPS53
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Evidence at protein level
  • Annotation score
    1/5

Function

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentcytosol
Cellular ComponentGARP complex
Biological Processretrograde transport, endosome to Golgi

Names & Taxonomy

Subcellular Location

Disease & Variants

Variants

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The viewer provides 934 variants from UniProt as well as other sources including ClinVar and dbSNP.

Go to variant viewer

Genetic variation databases

PTM/Processing

Features

Showing features for modified residue (large scale data).

TypeIDPosition(s)SourceDescription
Modified residue (large scale data)329PRIDEPhosphoserine
Modified residue (large scale data)333PRIDEPhosphoserine
Modified residue (large scale data)343PRIDEPhosphothreonine

Proteomic databases

Expression

Gene expression databases

Family & Domains

Features

Showing features for domain, coiled coil, region, compositional bias.

TypeIDPosition(s)Description
Domain41-227Vps53 N-terminal
Coiled coil97-138
Domain228-403Vps53 N-terminal
Region324-364Disordered
Compositional bias347-364Basic and acidic residues

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    547
  • Mass (Da)
    62,167
  • Last updated
    2011-07-27 v1
  • Checksum
    86C32EF00395070B
MMEEEELEFVEELEAVLQLTPEVQLAIEQVFPSQDPLDRADFNAVEYINTLFPTEQSLANIDEVVNKIRLKIRRLDDNIRTVVRGQTNVGQDGRQALEEAQKAIQQLFGKIKDIKDKAEKSEQMVKEITRDIKQLDHAKRHLTTSITTLNHLHMLAGGVDSLEAMTRRRQYGEVANLLQGVMNVLEHFHKYMGIPQIRQLSERVKAAQTELGQQILADFEEAFPSQGTKVAWLDKIDRRYAWIKRQLVDYEEKYGRMFPREWCMAERIAVEFCHVTRAELAKIMRTRAKEIEVKLLLFAIQRTTNFEGFLAKRFSGCTLTDGTLKKLESPPPSTNPFLEDEPTPEMEELATEKGDLDQPKKPKAPDNPFHGIVSKCFEPHLYVYIESQDKNLGELIDRFVADFKAQGPPKPNTDEGGAVLPSCADLFVYYKKCMVQCSQLSTGEPMIALTTIFQKYLREYAWKILSGNLPKTTTSSGGLTISSLLKEKEGSEVAKFTLEELCLICNILSTAEYCLATTQQLEEKLKEKVDRHLQQYSAAGSGSGCCL

Computationally mapped potential isoform sequences

There are 45 potential isoforms mapped to this entry

View all
EntryEntry nameGene nameLength
Q5VIR6VPS53_HUMANVPS53832
E7EVT8E7EVT8_HUMANVPS53422
A0A7P0T9V8A0A7P0T9V8_HUMANVPS53644
A0A7P0T9Z7A0A7P0T9Z7_HUMANVPS53136
A0A7P0T9X9A0A7P0T9X9_HUMANVPS53135
A0A7P0T8D0A0A7P0T8D0_HUMANVPS53109
A0A7P0T8A9A0A7P0T8A9_HUMANVPS5351
A0A7P0T8I9A0A7P0T8I9_HUMANVPS53117
A0A7P0T8K1A0A7P0T8K1_HUMANVPS53119
A0A7P0T8P7A0A7P0T8P7_HUMANVPS53680
A0A7P0T8S5A0A7P0T8S5_HUMANVPS53109
A0A7P0T8V1A0A7P0T8V1_HUMANVPS53464
A0A7P0T8V2A0A7P0T8V2_HUMANVPS5397
A0A7P0T8V9A0A7P0T8V9_HUMANVPS53106
A0A7P0T9B2A0A7P0T9B2_HUMANVPS53782
A0A7P0T9B6A0A7P0T9B6_HUMANVPS53166
A0A7P0T804A0A7P0T804_HUMANVPS5378
A0A7P0T805A0A7P0T805_HUMANVPS53253
A0A7P0T874A0A7P0T874_HUMANVPS53673
A0A7P0T7U9A0A7P0T7U9_HUMANVPS53133
A0A7P0T8A5A0A7P0T8A5_HUMANVPS53233
A0A7P0TB80A0A7P0TB80_HUMANVPS53422
A0A7P0TBG3A0A7P0TBG3_HUMANVPS5383
A0A7P0TBJ8A0A7P0TBJ8_HUMANVPS53216
A0A7P0TBK3A0A7P0TBK3_HUMANVPS53237
A0A7P0TA41A0A7P0TA41_HUMANVPS53133
A0A7P0TA53A0A7P0TA53_HUMANVPS53242
A0A7P0TA79A0A7P0TA79_HUMANVPS53546
A0A7P0TA82A0A7P0TA82_HUMANVPS5380
A0A7P0TAE0A0A7P0TAE0_HUMANVPS53655
A0A7P0TAF8A0A7P0TAF8_HUMANVPS53293
A0A7P0TAK4A0A7P0TAK4_HUMANVPS53631
A0A7P0TB16A0A7P0TB16_HUMANVPS53372
A0A7P0Z4K0A0A7P0Z4K0_HUMANVPS53572
A0A7P0Z4M8A0A7P0Z4M8_HUMANVPS53104
A0A7P0Z4Q7A0A7P0Z4Q7_HUMANVPS53337
A0A7P0Z400A0A7P0Z400_HUMANVPS53709
A0A7P0Z461A0A7P0Z461_HUMANVPS53643
I3L4P9I3L4P9_HUMANVPS53203
I3L1W6I3L1W6_HUMANVPS5381
I3L184I3L184_HUMANVPS53342
I3L0S6I3L0S6_HUMANVPS53216
A0AAG2TC49A0AAG2TC49_HUMANVPS5368
A0AAG2TFL7A0AAG2TFL7_HUMANVPS53237
A0AAG2TET0A0AAG2TET0_HUMANVPS53145

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias347-364Basic and acidic residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AC015853
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.
AC027455
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.
KC877627
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.
KC877635
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.

Genome annotation databases

Similar Proteins

Disclaimer

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