Lineage-specific biology revealed by a finished genome assembly of the mouse.Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X., Bult C.J., Agarwala R., Cherry J.L.[...], Ponting C.P.View abstractCited forNUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]StrainC57BL/6JCategorySequencesSourceUniProtKB unreviewed (TrEMBL)PubMedEurope PMCPLoS Biol. 7:E1000112-E1000112 (2009)Cited in99+99+
A tissue-specific atlas of mouse protein phosphorylation and expression.Huttlin E.L., Jedrychowski M.P., Elias J.E., Goswami T., Rad R., Beausoleil S.A., Villen J., Haas W., Sowa M.E., Gygi S.P.View abstractCited forIDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]CategorySequencesSourceUniProtKB unreviewed (TrEMBL)PubMedEurope PMCCell 143:1174-1189 (2010)Cited in99+99+Mapped to6
Modernizing reference genome assemblies.Church D.M., Schneider V.A., Graves T., Auger K., Cunningham F., Bouk N., Chen H.C., Agarwala R., McLaren W.M.[...], Hubbard T.Cited forNUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]StrainC57BL/6JCategorySequencesSourceUniProtKB unreviewed (TrEMBL)PubMedEurope PMCPLoS Biol 9:e1001091-e1001091 (2011)Cited in99+
No title available.EnsemblCited forIDENTIFICATIONStrainC57BL/6JSourceUniProtKB unreviewed (TrEMBL)Submission Submitted to UniProtKB (AUG-2024)Cited in99+
Mitogen-activated protein kinases activate the serine/threonine kinases Mnk1 and Mnk2.Waskiewicz A.J., Flynn A., Proud C.G., Cooper J.A.View abstractCategoryPTM / ProcessingSourceMGI: 894316PubMedEurope PMCEMBO J. 16:1909-1920 (1997)Cited in2Mapped to49
Vinorelbine causes a neuropathic pain-like state in mice via STING and MNK1 signaling associated with type I interferon induction.Franco-Enzastiga U., Natarajan K., David E.T., Patel K., Ravirala A., Price T.J.View abstractCategoryFunctionSourceMGI: 894316PubMedEurope PMCiScience 27:108808-108808 (2024)Mapped to17
MAPK-interacting kinase 1 regulates platelet production, activation, and thrombosis.Manne B.K., Campbell R.A., Bhatlekar S., Ajanel A., Denorme F., Portier I., Middleton E.A., Tolley N.D., Kosaka Y.[...], Rondina M.T.View abstractCategoryFunctionSourceMGI: 894316PubMedEurope PMCBlood 140:2477-2489 (2022)Mapped to9
Circadian activities of the brain MNK-eIF4E signalling axis contribute to diurnal rhythms of some cognitive functions.Liu D., Li J., Lin H., Lorsung E., Le N., Singla R., Mishra A., Fukunaga R., Cao R.View abstractCategoryFunctionSourceMGI: 894316PubMedEurope PMCEur J Neurosci 56:3553-3569 (2022)Mapped to25
Type I Interferons Act Directly on Nociceptors to Produce Pain Sensitization: Implications for Viral Infection-Induced Pain.Barragan-Iglesias P., Franco-Enzastiga U., Jeevakumar V., Shiers S., Wangzhou A., Granados-Soto V., Campbell Z.T., Dussor G., Price T.J.View abstractCategoryFunctionSourceMGI: 894316PubMedEurope PMCJ Neurosci 40:3517-3532 (2020)Mapped to17
Nociceptor Translational Profiling Reveals the Ragulator-Rag GTPase Complex as a Critical Generator of Neuropathic Pain.Megat S., Ray P.R., Moy J.K., Lou T.F., Barragan-Iglesias P., Li Y., Pradhan G., Wanghzou A., Ahmad A.[...], Price T.J.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 894316PubMedEurope PMCJ Neurosci 39:393-411 (2019)Mapped to23
Translational control of depression-like behavior via phosphorylation of eukaryotic translation initiation factor 4E.Aguilar-Valles A., Haji N., De Gregorio D., Matta-Camacho E., Eslamizade M.J., Popic J., Sharma V., Cao R., Rummel C.[...], Sonenberg N.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 894316PubMedEurope PMCNat Commun 9:2459-2459 (2018)Mapped to25
The MNK-eIF4E Signaling Axis Contributes to Injury-Induced Nociceptive Plasticity and the Development of Chronic Pain.Moy J.K., Khoutorsky A., Asiedu M.N., Black B.J., Kuhn J.L., Barragan-Iglesias P., Megat S., Burton M.D., Burgos-Vega C.C.[...], Price T.J.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 894316PubMedEurope PMCJ Neurosci 37:7481-7499 (2017)Mapped to25
Mycobacterium tuberculosis subverts negative regulatory pathways in human macrophages to drive immunopathology.Brace P.T., Tezera L.B., Bielecka M.K., Mellows T., Garay D., Tian S., Rand L., Green J., Jogai S.[...], Elkington P.T.View abstractCategoryFunctionSourceMGI: 894316PubMedEurope PMCPLoS Pathog 13:e1006367-e1006367 (2017)Mapped to17
MNK1 and MNK2 mediate adverse effects of high-fat feeding in distinct ways.Moore C.E., Pickford J., Cagampang F.R., Stead R.L., Tian S., Zhao X., Tang X., Byrne C.D., Proud C.G.View abstractCategoryFunctionSourceMGI: 894316PubMedEurope PMCSci Rep 6:23476-23476 (2016)Mapped to17
BDNF stimulation of protein synthesis in cortical neurons requires the MAP kinase-interacting kinase MNK1.Genheden M., Kenney J.W., Johnston H.E., Manousopoulou A., Garbis S.D., Proud C.G.View abstractCategoryInteractionSourceMGI: 894316PubMedEurope PMCJ Neurosci 35:972-984 (2015)Mapped to23
The MAP kinase-interacting kinases regulate cell migration, vimentin expression and eIF4E/CYFIP1 binding.Beggs J.E., Tian S., Jones G.G., Xie J., Iadevaia V., Jenei V., Thomas G., Proud C.G.View abstractCategoryInteractionSourceMGI: 894316PubMedEurope PMCBiochem J 467:63-76 (2015)Mapped to53
Two-stage translational control of dentate gyrus LTP consolidation is mediated by sustained BDNF-TrkB signaling to MNK.Panja D., Kenney J.W., D'Andrea L., Zalfa F., Vedeler A., Wibrand K., Fukunaga R., Bagni C., Proud C.G., Bramham C.R.View abstractCategoryFunctionSourceMGI: 894316PubMedEurope PMCCell Rep 9:1430-1445 (2014)Mapped to38
Rapamycin enhances eIF4E phosphorylation by activating MAP kinase- interacting kinase 2a (Mnk2a).Stead R.L., Proud C.G.View abstractCategoryPTM / ProcessingSourceMGI: 894316PubMedEurope PMCFEBS Lett 587:2623-2628 (2013)Mapped to44
Mnk1 and 2 are dispensable for T cell development and activation but important for the pathogenesis of experimental autoimmune encephalomyelitis.Gorentla B.K., Krishna S., Shin J., Inoue M., Shinohara M.L., Grayson J.M., Fukunaga R., Zhong X.P.View abstractCategoryPTM / ProcessingSourceMGI: 894316PubMedEurope PMCJ Immunol 190:1026-1037 (2013)Mapped to38
p38alpha mitogen-activated protein kinase depletion and repression of signal transduction to translation machinery by miR-124 and -128 in neurons.Lawson S.K., Dobrikova E.Y., Shveygert M., Gromeier M.View abstractCategoryFunctionSourceMGI: 894316PubMedEurope PMCMol Cell Biol 33:127-135 (2013)Mapped to20
Translational control of the activation of transcription factor NF-kappaB and production of type I interferon by phosphorylation of the translation factor eIF4E.Herdy B., Jaramillo M., Svitkin Y.V., Rosenfeld A.B., Kobayashi M., Walsh D., Alain T., Sean P., Robichaud N.[...], Sonenberg N.View abstractCategoryFunctionSourceMGI: 894316PubMedEurope PMCNat Immunol 13:543-550 (2012)Mapped to25
MNK2 inhibits eIF4G activation through a pathway involving serine- arginine-rich protein kinase in skeletal muscle.Hu S.I., Katz M., Chin S., Qi X., Cruz J., Ibebunjo C., Zhao S., Chen A., Glass D.J.View abstractCategoryPTM / ProcessingSourceMGI: 894316PubMedEurope PMCSci Signal 5:ra14-ra14 (2012)Mapped to52
A conditional knockout resource for the genome-wide study of mouse gene function.Skarnes W.C., Rosen B., West A.P., Koutsourakis M., Bushell W., Iyer V., Mujica A.O., Thomas M., Harrow J.[...], Bradley A.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 894316PubMedEurope PMCNature 474:337-342 (2011)Mapped to99+
A high-resolution anatomical atlas of the transcriptome in the mouse embryo.Diez-Roux G., Banfi S., Sultan M., Geffers L., Anand S., Rozado D., Magen A., Canidio E., Pagani M.[...], Ballabio A.View abstractCategoryExpressionSourceMGI: 894316PubMedEurope PMCPLoS Biol 9:e1000582-e1000582 (2011)Mapped to99+
Combined deficiency for MAP kinase-interacting kinase 1 and 2 (Mnk1 and Mnk2) delays tumor development.Ueda T., Sasaki M., Elia A.J., Chio I.I., Hamada K., Fukunaga R., Mak T.W.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 894316PubMedEurope PMCProc Natl Acad Sci U S A 107:13984-13990 (2010)Mapped to27