F6VSN1 · F6VSN1_MACMU
- ProteinCap-specific mRNA (nucleoside-2'-O-)-methyltransferase 2
- GeneCMTR2
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids770 (go to sequence)
- Protein existencePredicted
- Annotation score2/5
Function
Catalytic activity
- a 5'-end (N7-methyl 5'-triphosphoguanosine)-(2'-O-methyl-ribonucleoside)-(ribonucleotide) in mRNA + S-adenosyl-L-methionine = a 5'-end (N7-methyl 5'-triphosphoguanosine)-(2'-O-methyl-ribonucleoside)-(2'-O-methyl-ribonucleotide) in mRNA + S-adenosyl-L-homocysteine + H+
Features
Showing features for binding site, active site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 148 | S-adenosyl-L-methionine (UniProtKB | ChEBI) | |||
Binding site | 167 | S-adenosyl-L-methionine (UniProtKB | ChEBI) | |||
Binding site | 235 | S-adenosyl-L-methionine (UniProtKB | ChEBI) | |||
Active site | 275 | Proton acceptor | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Cellular Component | nucleus | |
Molecular Function | mRNA (nucleoside-2'-O-)-methyltransferase activity | |
Biological Process | 7-methylguanosine mRNA capping | |
Biological Process | methylation |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameCap-specific mRNA (nucleoside-2'-O-)-methyltransferase 2
- EC number
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Primates > Haplorrhini > Catarrhini > Cercopithecidae > Cercopithecinae > Macaca
Accessions
- Primary accessionF6VSN1
Proteomes
Organism-specific databases
Subcellular Location
UniProt Annotation
GO Annotation
PTM/Processing
Proteomic databases
Expression
Gene expression databases
Interaction
Protein-protein interaction databases
Structure
Sequence
- Sequence statusComplete
- Length770
- Mass (Da)88,070
- Last updated2019-12-11 v2
- Checksum1D1C31862BC0A0F3
Keywords
- Technical term