F6VQD1 · F6VQD1_XENTR

Function

function

DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability.

Catalytic activity

Cofactor

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Features

Showing features for binding site, dna binding.

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Type
IDPosition(s)Description
Binding site229-236ATP (UniProtKB | ChEBI)
DNA binding544-563

GO annotations

AspectTerm
Cellular Componentmitochondrion
Cellular Componentnucleus
Molecular Function5'-3' DNA helicase activity
Molecular FunctionATP binding
Molecular FunctionATP hydrolysis activity
Molecular FunctionDNA binding
Biological ProcessDNA recombination
Biological ProcessDNA repair
Biological Processmitochondrial genome maintenance
Biological Processtelomere maintenance

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    ATP-dependent DNA helicase PIF1
  • EC number
  • Alternative names
    • DNA repair and recombination helicase PIF1

Gene names

    • Name
      pif1
    • Synonyms
      PIF1

Organism names

Accessions

  • Primary accession
    F6VQD1

Organism-specific databases

Subcellular Location

Keywords

PTM/Processing

Proteomic databases

Expression

Gene expression databases

Interaction

Subunit

Monomer.

Protein-protein interaction databases

Family & Domains

Features

Showing features for region, compositional bias, domain.

Type
IDPosition(s)Description
Region150-187Disordered
Compositional bias169-187Polar residues
Domain221-407AAA+ ATPase

Sequence similarities

Belongs to the helicase family. PIF1 subfamily.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    602
  • Mass (Da)
    67,171
  • Last updated
    2021-06-02 v4
  • MD5 Checksum
    EBFA71613851E6EA24B71E26C8664677
MMLAEQLSPEIQSSITIEYLNSSGQTLKRKAIRNALVSLGRNEFRDLVLKVSDGKLQQNFVLKQIKLFTRFIRDGKASVVLLPENVQLLISNCPSDKLQHFMKTLLIKHEAGKTEKPVNERTRLLSGLPRVFETISPVQKKDVEQANEMRAKANSETPVKGRGLSNKGVNGVNRCQQKRTRTESSNSLIADLRPSKKPTLSMPKQVRLSTEQSLVLNTVLSGRNVFFTGSAGTGKSYLLKRIVGALPPKSTYATASTGVAACHIGGTTLHAFAGIGTGKASIEQCIELAKRPGVRQHWTGCKHLIIDEISMVEGEFFDKLEAVARAVRGKDEPFGGIQLIVCGDFLQLPPVTQASSQTKFCFQARSWRKCIHLTMELTEVRRQTDKNFISLLQAIRLGRYIIHLSTRLKDLGESHLYEALDSDPMLVKTINAQCPVNQQIQLKKGAQVMLAKNLDVSRGLVNGARGVVTKFEEGNKNLPVVRFLCGVTEVIKPDRWVFKGHGGIYLSRQQLPLKLAWAISIHKSQGMSLDCVEISLSRVFESGQAYVALSRARNLEGLRVMDFDPKVVRANPYVLQFYSQMRKERALRQTCLEDFLENKENC

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias169-187Polar residues

Genome annotation databases

Similar Proteins

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