F6VQD1 · F6VQD1_XENTR
- ProteinATP-dependent DNA helicase PIF1
- Genepif1
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids602 (go to sequence)
- Protein existenceInferred from homology
- Annotation score4/5
Function
function
DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability.
Catalytic activity
- ATP + H2O = ADP + phosphate + H+
Cofactor
Features
Showing features for binding site, dna binding.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 229-236 | ATP (UniProtKB | ChEBI) | |||
DNA binding | 544-563 | ||||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | mitochondrion | |
Cellular Component | nucleus | |
Molecular Function | 5'-3' DNA helicase activity | |
Molecular Function | ATP binding | |
Molecular Function | ATP hydrolysis activity | |
Molecular Function | DNA binding | |
Biological Process | DNA recombination | |
Biological Process | DNA repair | |
Biological Process | mitochondrial genome maintenance | |
Biological Process | telomere maintenance |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameATP-dependent DNA helicase PIF1
- EC number
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Amphibia > Batrachia > Anura > Pipoidea > Pipidae > Xenopodinae > Xenopus > Silurana
Accessions
- Primary accessionF6VQD1
Organism-specific databases
Subcellular Location
PTM/Processing
Proteomic databases
Expression
Gene expression databases
Interaction
Structure
Family & Domains
Features
Showing features for region, compositional bias, domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Region | 150-187 | Disordered | |||
Compositional bias | 169-187 | Polar residues | |||
Domain | 221-407 | AAA+ ATPase | |||
Sequence similarities
Belongs to the helicase family. PIF1 subfamily.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length602
- Mass (Da)67,171
- Last updated2021-06-02 v4
- MD5 ChecksumEBFA71613851E6EA24B71E26C8664677
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Compositional bias | 169-187 | Polar residues | |||