F6U9W6 · F6U9W6_HORSE
- ProteinTyrosine-protein phosphatase non-receptor type
- GenePTPN6
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids597 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score5/5
Function
Catalytic activity
- O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate
Features
Showing features for binding site, active site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 421 | substrate | |||
Active site | 455 | Phosphocysteine intermediate | |||
Binding site | 502 | substrate | |||
GO annotations
Keywords
- Molecular function
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameTyrosine-protein phosphatase non-receptor type
- EC number
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Laurasiatheria > Perissodactyla > Equidae > Equus
Accessions
- Primary accessionF6U9W6
Proteomes
Organism-specific databases
Subcellular Location
Expression
Gene expression databases
Structure
Family & Domains
Features
Showing features for domain, region, compositional bias.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Domain | 6-102 | SH2 | |||
Domain | 112-215 | SH2 | |||
Domain | 246-517 | Tyrosine-protein phosphatase | |||
Domain | 432-508 | Tyrosine specific protein phosphatases | |||
Region | 533-597 | Disordered | |||
Compositional bias | 556-591 | Basic and acidic residues | |||
Sequence similarities
Belongs to the protein-tyrosine phosphatase family. Non-receptor class 2 subfamily.
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length597
- Mass (Da)67,624
- Last updated2023-09-13 v2
- ChecksumB32406A210D25901
Computationally mapped potential isoform sequences
There is 1 potential isoform mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
A0A5F5PWB4 | A0A5F5PWB4_HORSE | PTPN6 | 558 |
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Compositional bias | 556-591 | Basic and acidic residues | |||
Keywords
- Technical term