F6U6X3 · F6U6X3_MOUSE

  • Protein
    Dual specificity tyrosine-phosphorylation-regulated kinase 1A
  • Gene
    Dyrk1a
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Evidence at protein level
  • Annotation score
    3/5

Function

Catalytic activity

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site150ATP (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentnuclear speck
Molecular FunctionATP binding
Molecular Functionprotein serine/threonine kinase activity
Molecular Functionprotein serine/threonine/tyrosine kinase activity

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Dual specificity tyrosine-phosphorylation-regulated kinase 1A
  • EC number
  • Alternative names
    • Protein kinase minibrain homolog

Gene names

    • Name
      Dyrk1a

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • C57BL/6J
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Glires > Rodentia > Myomorpha > Muroidea > Muridae > Murinae > Mus > Mus

Accessions

  • Primary accession
    F6U6X3

Proteomes

Organism-specific databases

Subcellular Location

Keywords

  • Cellular component

PTM/Processing

Proteomic databases

Expression

Gene expression databases

Structure

Family & Domains

Features

Showing features for region, compositional bias, domain.

TypeIDPosition(s)Description
Region1-51Disordered
Compositional bias9-46Polar residues
Region74-99Disordered
Domain121-441Protein kinase
Region370-404Disordered
Compositional bias447-490Polar residues
Region447-502Disordered
Region558-641Disordered
Compositional bias563-586Basic residues
Compositional bias589-641Polar residues

Sequence similarities

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    725
  • Mass (Da)
    81,509
  • Last updated
    2018-10-10 v1
  • Checksum
    08C20670AF349DDF
MAAQMPHSHQYSDRRQPSISDQQVSALPYSDQIQQPLTNQRRMPQTFRDPATAPLRKLSVDLIKTYKHINEVYYAKKKRRHQQGQGDDSSHKKERKVYNDGYDDDNYDYIVKNGEKWMDRYEIDSLIGKGSFGQVVKAYDRVEQEWVAIKIIKNKKAFLNQAQIEVRLLELMNKHDTEMKYYIVHLKRHFMFRNHLCLVFEMLSYNLYDLLRNTNFRGVSLNLTRKFAQQMCTALLFLATPELSIIHCDLKPENILLCNPKRSAIKIVDFGSSCQLGQRIYQYIQSRFYRSPEVLLGMPYDLAIDMWSLGCILVEMHTGEPLFSGANEVDQMNKIVEVLGIPPAHILDQAPKARKFFEKLPDGTWSLKKTKDGKREYKPPGTRKLHNILGVETGGPGGRRAGESGHTVADYLKFKDLILRMLDYDPKTRIQPYYALQHSFFKKTADEGTNTSNSVSTSPAMEQSQSSGTTSSTSSSSGGSSGTSNSGRARSDPTHQHRHSGGHFAAAVQAMDCETHSPQVRQQFPAPLGWSGTEAPTQVTVETHPVQETTFHVAPQQNALHHHHGNSSHHHHHHHHHHHHHGQQALGNRTRPRVYNSPTNSSSTQDSMEVGHSHHSMTSLSSSTTSSSTSSSSTGNQGNQAYQNRPVAANTLDFGQNGAMDVNLTVYSNPRQETGIAGHPTYQFSANTGPAHYMTEGHLAMRQGADREESPMTGVCVQQSPVASS

Computationally mapped potential isoform sequences

There are 3 potential isoforms mapped to this entry

View all
EntryEntry nameGene nameLength
Q61214DYR1A_MOUSEDyrk1a763
A9C477A9C477_MOUSEDyrk1a110
A9C478A9C478_MOUSEDyrk1a181

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias9-46Polar residues
Compositional bias447-490Polar residues
Compositional bias563-586Basic residues
Compositional bias589-641Polar residues

Keywords

Sequence databases

Genome annotation databases

Similar Proteins

Disclaimer

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