F6U6X3 · F6U6X3_MOUSE
- ProteinDual specificity tyrosine-phosphorylation-regulated kinase 1A
- GeneDyrk1a
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids725 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score3/5
Function
Catalytic activity
- ATP + L-seryl-[protein] = ADP + H+ + O-phospho-L-seryl-[protein]
Features
Showing features for binding site.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | nuclear speck | |
Molecular Function | ATP binding | |
Molecular Function | protein serine/threonine kinase activity | |
Molecular Function | protein serine/threonine/tyrosine kinase activity |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameDual specificity tyrosine-phosphorylation-regulated kinase 1A
- EC number
- Alternative names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Glires > Rodentia > Myomorpha > Muroidea > Muridae > Murinae > Mus > Mus
Accessions
- Primary accessionF6U6X3
Proteomes
Organism-specific databases
Subcellular Location
PTM/Processing
Proteomic databases
Expression
Gene expression databases
Structure
Family & Domains
Features
Showing features for region, compositional bias, domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Region | 1-51 | Disordered | ||||
Sequence: MAAQMPHSHQYSDRRQPSISDQQVSALPYSDQIQQPLTNQRRMPQTFRDPA | ||||||
Compositional bias | 9-46 | Polar residues | ||||
Sequence: HQYSDRRQPSISDQQVSALPYSDQIQQPLTNQRRMPQT | ||||||
Region | 74-99 | Disordered | ||||
Sequence: YAKKKRRHQQGQGDDSSHKKERKVYN | ||||||
Domain | 121-441 | Protein kinase | ||||
Sequence: YEIDSLIGKGSFGQVVKAYDRVEQEWVAIKIIKNKKAFLNQAQIEVRLLELMNKHDTEMKYYIVHLKRHFMFRNHLCLVFEMLSYNLYDLLRNTNFRGVSLNLTRKFAQQMCTALLFLATPELSIIHCDLKPENILLCNPKRSAIKIVDFGSSCQLGQRIYQYIQSRFYRSPEVLLGMPYDLAIDMWSLGCILVEMHTGEPLFSGANEVDQMNKIVEVLGIPPAHILDQAPKARKFFEKLPDGTWSLKKTKDGKREYKPPGTRKLHNILGVETGGPGGRRAGESGHTVADYLKFKDLILRMLDYDPKTRIQPYYALQHSFF | ||||||
Region | 370-404 | Disordered | ||||
Sequence: TKDGKREYKPPGTRKLHNILGVETGGPGGRRAGES | ||||||
Compositional bias | 447-490 | Polar residues | ||||
Sequence: EGTNTSNSVSTSPAMEQSQSSGTTSSTSSSSGGSSGTSNSGRAR | ||||||
Region | 447-502 | Disordered | ||||
Sequence: EGTNTSNSVSTSPAMEQSQSSGTTSSTSSSSGGSSGTSNSGRARSDPTHQHRHSGG | ||||||
Region | 558-641 | Disordered | ||||
Sequence: NALHHHHGNSSHHHHHHHHHHHHHGQQALGNRTRPRVYNSPTNSSSTQDSMEVGHSHHSMTSLSSSTTSSSTSSSSTGNQGNQA | ||||||
Compositional bias | 563-586 | Basic residues | ||||
Sequence: HHGNSSHHHHHHHHHHHHHGQQAL | ||||||
Compositional bias | 589-641 | Polar residues | ||||
Sequence: RTRPRVYNSPTNSSSTQDSMEVGHSHHSMTSLSSSTTSSSTSSSSTGNQGNQA |
Sequence similarities
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length725
- Mass (Da)81,509
- Last updated2018-10-10 v1
- Checksum08C20670AF349DDF
Computationally mapped potential isoform sequences
There are 3 potential isoforms mapped to this entry
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 9-46 | Polar residues | ||||
Sequence: HQYSDRRQPSISDQQVSALPYSDQIQQPLTNQRRMPQT | ||||||
Compositional bias | 447-490 | Polar residues | ||||
Sequence: EGTNTSNSVSTSPAMEQSQSSGTTSSTSSSSGGSSGTSNSGRAR | ||||||
Compositional bias | 563-586 | Basic residues | ||||
Sequence: HHGNSSHHHHHHHHHHHHHGQQAL | ||||||
Compositional bias | 589-641 | Polar residues | ||||
Sequence: RTRPRVYNSPTNSSSTQDSMEVGHSHHSMTSLSSSTTSSSTSSSSTGNQGNQA |
Keywords
- Technical term