F6TVP2 · F6TVP2_MOUSE

  • Protein
    Deoxynucleoside triphosphate triphosphohydrolase SAMHD1
  • Gene
    Samhd1
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Evidence at protein level
  • Annotation score
    3/5

Function

Catalytic activity

GO annotations

AspectTerm
Cellular Componentchromosome
Molecular Functioncatalytic activity
Molecular FunctionGTP binding
Molecular Functionmetal ion binding
Biological Processdefense response to virus
Biological ProcessDNA repair
Biological ProcessDNA replication

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Deoxynucleoside triphosphate triphosphohydrolase SAMHD1

Gene names

    • Name
      Samhd1

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • C57BL/6J
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Glires > Rodentia > Myomorpha > Muroidea > Muridae > Murinae > Mus > Mus

Accessions

  • Primary accession
    F6TVP2

Proteomes

Organism-specific databases

Subcellular Location

Keywords

Expression

Gene expression databases

Family & Domains

Features

Showing features for region, domain, compositional bias.

TypeIDPosition(s)Description
Region1-51Disordered
Domain57-122SAM
Domain176-328HD
Region606-631Disordered
Compositional bias616-631Polar residues

Sequence similarities

Belongs to the SAMHD1 family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Fragment
  • Length
    631
  • Mass (Da)
    72,858
  • Last updated
    2011-07-27 v1
  • Checksum
    E3B40F6C4DDB9639
XTSQPRVSEVAMQSAPLEQPAKRPRCDGSPRTPPSTPPATANLSADDDFQNTDLRTWEPEDVCSFLENRGFREKKVLDIFRDNKIAGSFLPFLDEDRLEDLGVSSLEERKKMIECIQQLSQSRIDLMKVFNDPIHGHIEFHPLLIRIIDTPQFQRLRYIKQLGGGYYVFPGASHNRFEHSLGVGYLAGCLVRALAEKQPELQISERDILCVQIAGLCHDLGHGPFSHMFDGRFIPRARPEKKWKHEQGSIEMFEHLVNSNELKLVMKNYGLVPEEDITFIKEQIMGPPITPVKDSLWPYKGRPATKSFLYEIVSNKRNGIDVDKWDYFARDCHHLGIQNNFDYKRFIKFARICEVEYKVKEDKTYIRKVKHICSREKEVGNLYDMFHTRNCLHRRAYQHKISNLIDIMITDAFLKADPYVEITGTAGKKFRISTAIDDMEAFTKLTDNIFLEVLHSTDPQLSEAQSILRNIECRNLYKYLGETQPKREKIRKEEYERLPQEVAKAKPEKAPDVELKAEDFIVDVINVDYGMEDKNPIDRVHFYCKSNSKQAVRINKEQVSQLLPEKFAEQLIRVYCKKKDGKSLDAAGKHFVQWCALRDFTKPQQCGAGEMAEDPDSIPSTQQPHAAHNQL

Computationally mapped potential isoform sequences

There are 3 potential isoforms mapped to this entry

View all
EntryEntry nameGene nameLength
Q60710SAMH1_MOUSESamhd1658
E9PYG9E9PYG9_MOUSESamhd1582
E0CXZ5E0CXZ5_MOUSESamhd1150

Features

Showing features for non-terminal residue, compositional bias.

TypeIDPosition(s)Description
Non-terminal residue1
Compositional bias616-631Polar residues

Keywords

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.
FeedbackHelp