F6TJ68 · F6TJ68_MONDO

Function

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentcytoplasm
Cellular Componentcytoplasmic dynein complex
Cellular Componentkinetochore
Cellular Componentmitotic spindle
Cellular Componentnuclear inclusion body
Cellular Componentnuclear membrane
Cellular Componentnuclear periphery
Cellular Componentnuclear pore
Cellular Componentnuclear pore nuclear basket
Molecular Functionchromatin binding
Molecular Functiondynein complex binding
Molecular Functionheat shock protein binding
Molecular Functionmitogen-activated protein kinase binding
Molecular FunctionmRNA binding
Molecular Functionprotein homodimerization activity
Molecular Functionstructural constituent of nuclear pore
Molecular Functiontubulin binding
Biological Processcellular response to interferon-alpha
Biological Processmitotic spindle assembly checkpoint signaling
Biological ProcessmRNA export from nucleus
Biological ProcessmRNA export from nucleus in response to heat stress
Biological Processnegative regulation of RNA export from nucleus
Biological Processnegative regulation of transcription by RNA polymerase II
Biological Processnegative regulation of translational initiation
Biological Processnuclear pore organization
Biological Processpositive regulation of heterochromatin formation
Biological Processpositive regulation of mitotic cell cycle spindle assembly checkpoint
Biological Processpositive regulation of protein import into nucleus
Biological Processprotein import into nucleus
Biological Processregulation of mitotic spindle assembly
Biological Processresponse to epidermal growth factor
Biological ProcessRNA import into nucleus

Names & Taxonomy

Protein names

  • Recommended name
    Nucleoprotein TPR

Gene names

    • Name
      TPR

Organism names

Accessions

  • Primary accession
    F6TJ68

Proteomes

Expression

Gene expression databases

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for coiled coil, domain, region, compositional bias.

Type
IDPosition(s)Description
Coiled coil29-165
Coiled coil219-281
Coiled coil321-366
Coiled coil427-513
Coiled coil543-596
Coiled coil666-802
Coiled coil828-1073
Domain1041-1168Nucleoprotein TPR/MLP1
Coiled coil1112-1171
Coiled coil1223-1425
Coiled coil1477-1532
Region1532-1552Disordered
Compositional bias1620-1637Basic and acidic residues
Region1620-1676Disordered
Compositional bias1638-1676Polar residues
Region1778-1797Disordered
Compositional bias1804-1828Polar residues
Region1804-2125Disordered
Compositional bias1880-1898Polar residues
Compositional bias1905-1941Polar residues
Compositional bias1945-1986Acidic residues
Compositional bias2001-2015Acidic residues
Compositional bias2016-2068Polar residues
Compositional bias2071-2090Pro residues
Compositional bias2229-2259Polar residues
Region2229-2364Disordered
Compositional bias2296-2325Polar residues

Sequence similarities

Belongs to the TPR family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    2,364
  • Mass (Da)
    267,372
  • Last updated
    2019-12-11 v3
  • MD5 Checksum
    5325591D776F6C43B0DE6CCCC5AD68DA
MAAVLQQVLERQELTKLPKPVQAKLEKFLADQQSEIDCLKGRHEKFKVESEQQYFEVEKRLSQCQERLVNEGRECQTLRQELERLCQQLKSVTEKNKELETAQDRYVTVQSQLTRANEELEAEKRDLVRTSERRSQELEYLTEDVKRLNEKLKESIASKGELQLKLDELQASDVSVKYREKRLEQEKELLHNQNTWLNTELKTKTDELLAVGREKGNEILELKCNLENKKEEVVRMEEQLNGLKTSNENLQKHVEDLLTKLKEAKEQQASMEEKFHNELNAHIKLSNLYKSAADDSEAKSNELTRAVDELHKLLKETGEANKGIQDHLMEVEESKAQMEKEMLEKIGKLERELENANDLLSASKRKGAILSEEELAAMSPTAAAVAKIVKPGMKLTELYNAYVETQDQLLLEKLENKRINKYLDEIVKEVEAKAPILKRQREEYERAQKAVASLSVKLEQAMKEIQRLQEDTDKANKHSSVLERDNQRMEIQVKDLSQQIRVLLMELEEARGNHVIRDEEVSSADISSSSEVISQHLVSYRNIEELQQQNQRLLVALRELGETREREEQETTSSRISELQIQLESALTELEQLRESRHHQMQLVDSIVRQRDMYRILLSQATGVVIPLQASSLEDVSLMSTPKHPSGVSQAISTPTPISTVESTEAIEARAALKQLQEIFENYKKEKAENDKIQNEQSEKLQEQITDLRSQNTKISTQLDFASKRYEMLQDNVEGYRREITSLQERNQKLTATTQKQEQIINTMTQDLRGANEKLAVAEVRAENLKKEKEMLKLSEVRLSQQRESLLAEQRGQNLLLTNLQTIQGILERSETETKQRLNNQIEKLEREIAQLKKKLENEVEQRHTLTRNQDVQLLDTKRQLETEINRHLNTKELLKNAQKEIVTLKQQLSNIEAQLASQSAQRALGKGQSTTKEDIDDLISQLRQAEEQINDLKERLKTTSSNVEQYRAMVLSLEESLNKEKQVTEEVRKNVEARLKDSAEYQAQLEKKLMEAEKEKQELQDEKRRALESMEHQLSELKKTLTSVQNEVQEALQRASTALSNEQQARRDCQEQAKIAIEAQNKYERELMLHAADVEALQAAKEQVSKNLLVRQQLEEMAQKAESQLLECKASWEERERMLKDEASKSASRCEDLEKQNRLLHDQIEKLSDKVVTSMKEDVQGSSNVSLNEEGKSQEQVLEILRFIRREKEIAETRFEVAQVESLRYRQRVELLERELQELQDSLNAEREKVQVTAKTMAQHEELMKKTETMNVVIETNKMLREEKERLEQELQQMQAKVRKLELDILPLQESNAELSEKSGMLQAEKKLLEEDIKRWKARNQHLASQQKEPDLEECRKLLSEKEVNTKRIQQLTEETGRLKAEIARSNASLTTSQNLIQNLREELNKMRTEKESLQKDLEAKVTDIQEKVKTITQVKKIGRRYKTQYEELKAQHDKVMETSQSVGEPLEQQMSVHEVQELKETLNQAEIKTKSLENQIENLHKTVSEKESEVRNLQEQITQLQSELSRLHQDLQDRTTQEEQLRQHMTEKEDKTRKALVAAKAKLAHLAGVKDQLTKENEELKQRNGALDQQKDELDVRMTALKSQYEGRISRLERELREQQERHLEQRDEPQETTSKVPEQQRQITLKTTPASGERGIASTSDPPTANIKPTPVVSTPSKVTAAAIAGNKSTPRASIRPMVTPATVTNPTTTPTATVMPTTQVESQEAMQSEGPVDHVPVFGSTSGSVRSTSPNVQPSISQPILTVQQQTQATAFVQPTQQSHPQIEPASQELSPSIVEVVQSSPIERPSTSTAVFGTVSATPSSSLPKRAREEEDDSTIETSEQTSEETIEMPLPKKLKSIPPVGPEEEVTAEESTDGEVETLVNQDSQDSIGEGVTQGDYTPMEDSEETSQSLQIDLGPLQSDQQNPASGQDTQSKGDDVIVIDSDDEDDDDDENDGEQEDYEEDEDDDDDDDDEDTGMGDEGEDSNEGTGSADGNDGYEADDAEGGDATDPGTETEESTGGESNQRAADSQNGGEGGSIITESSLPHENSREQQPSSASERQGPRAPQSPRRPPHPLPPRLTIHAPPQELGPPVQRIQMTRRQSVGRGLQLTPGIGGMQQHFFDDEDRTVPSTPTLVVPHRTDGFAEAIHSPQVAGVPRFRFGPPEDMPQTSSSHSDLGQLASQGGLGMYETPLFLAHEEESGGRSVPTTPLQVAAPVTVFTESTTADASEHASQSVPMVTTSTGSLSTTTETGAGDDGDEVFVETESEGISSEAGLEIDSQQEEEPVQASDESDLPSTSQDPPSSSSADTSSNQPKPFRRVRLQPQTLRTGVRGRQFNRQRGVTHAMGGRGGLNRGNIN

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias1620-1637Basic and acidic residues
Compositional bias1638-1676Polar residues
Compositional bias1804-1828Polar residues
Compositional bias1880-1898Polar residues
Compositional bias1905-1941Polar residues
Compositional bias1945-1986Acidic residues
Compositional bias2001-2015Acidic residues
Compositional bias2016-2068Polar residues
Compositional bias2071-2090Pro residues
Compositional bias2229-2259Polar residues
Compositional bias2296-2325Polar residues

Keywords

Genome annotation databases

Similar Proteins

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