F6M3L4 · F6M3L4_ARATH

Function

function

Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by PDX2. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Also plays an indirect role in resistance to singlet oxygen-generating photosensitizers.

Catalytic activity

Pathway

Cofactor biosynthesis; pyridoxal 5'-phosphate biosynthesis.

Features

Showing features for binding site, active site.

130920406080100120140160180200220240260280300
TypeIDPosition(s)Description
Binding site40D-ribose 5-phosphate (UniProtKB | ChEBI)
Active site97Schiff-base intermediate with D-ribose 5-phosphate
Binding site169D-ribose 5-phosphate (UniProtKB | ChEBI)
Binding site181D-glyceraldehyde 3-phosphate (UniProtKB | ChEBI)
Binding site230D-ribose 5-phosphate (UniProtKB | ChEBI)
Binding site251-252D-ribose 5-phosphate (UniProtKB | ChEBI)

GO annotations

AspectTerm
Molecular Functionamine-lyase activity
Biological Processamino acid metabolic process
Biological Processpyridoxal phosphate biosynthetic process
Biological Processpyridoxine biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    pyridoxal 5'-phosphate synthase (glutamine hydrolyzing)
  • EC number

Gene names

    • Name
      PDX1.3

Organism names

  • Taxonomic identifier
  • Taxonomic lineage
    Eukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > rosids > malvids > Brassicales > Brassicaceae > Camelineae > Arabidopsis

Accessions

  • Primary accession
    F6M3L4
  • Secondary accessions
    • A0A178UIV6

Organism-specific databases

Genome annotation databases

Expression

Gene expression databases

Structure

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain23-228PdxS/SNZ N-terminal

Sequence similarities

Belongs to the PdxS/SNZ family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    309
  • Mass (Da)
    33,216
  • Last updated
    2011-07-27 v1
  • Checksum
    E74EBBCD4F124456
MEGTGVVAVYGNGAITEAKKSPFSVKVGLAQMLRGGVIMDVVNAEQARIAEEAGACAVMALERVPADIRAQGGVARMSDPQMIKEIKQAVTIPVMAKARIGHFVEAQILEAIGIDYIDESEVLTLADEDHHINKHNFRIPFVCGCRNLGEALRRIREGAAMIRTKGEAGTGNIIEAVRHVRSVNGDIRVLRNMDDDEVFTFAKKLAAPYDLVMQTKQLGRLPVVQFAAGGVATPADAALMMQLGCDGVFVGSGIFKSGDPARRARAIVQAVTHYSDPEMLVEVSCGLGEAMVGINLNDEKVERFANRSE

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
JF714983
EMBL· GenBank· DDBJ
AEF15886.1
EMBL· GenBank· DDBJ
mRNA

Genome annotation databases

Similar Proteins

Disclaimer

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