F5Z0P2 · F5Z0P2_MYCSD
- ProteinChaperonin GroEL
- GenegroEL
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids541 (go to sequence)
- Protein existenceInferred from homology
- Annotation score4/5
Function
function
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
Catalytic activity
Features
Showing features for binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 29-32 | ATP (UniProtKB | ChEBI) | |||
Binding site | 86-90 | ATP (UniProtKB | ChEBI) | |||
Binding site | 413 | ATP (UniProtKB | ChEBI) | |||
Binding site | 476-478 | ATP (UniProtKB | ChEBI) | |||
Binding site | 492 | ATP (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | capsule | |
Cellular Component | cell surface | |
Cellular Component | GroEL-GroES complex | |
Molecular Function | ATP binding | |
Molecular Function | ATP-dependent protein folding chaperone | |
Molecular Function | isomerase activity | |
Molecular Function | unfolded protein binding | |
Biological Process | chaperone cofactor-dependent protein refolding | |
Biological Process | protein refolding | |
Biological Process | response to heat |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameChaperonin GroEL
- EC number
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Actinomycetota > Actinomycetes > Mycobacteriales > Mycobacteriaceae > Mycolicibacter
Accessions
- Primary accessionF5Z0P2
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Keywords
- Cellular component
Interaction
Subunit
Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
Protein-protein interaction databases
Structure
Sequence
- Sequence statusComplete
- Length541
- Mass (Da)56,535
- Last updated2011-07-27 v1
- MD5 ChecksumA7A0E8B28968C0312F28F8D0C7A41A25
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
CP002329 EMBL· GenBank· DDBJ | AEF34431.1 EMBL· GenBank· DDBJ | Genomic DNA |